CA116001/MORAB-202-G000-205: A Phase 2 Open-label Randomized Study of Farletuzumab Ecteribulin (MORAb-202), a Folate Receptor Alpha-targeting Antibodydrug Conjugate, versus Investigators Choice Chemotherapy in Women with Platinumresistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian TubeCancer
Study of MORAb-202 in Women with Ovarian, Fallopian, or Primary Peritoneal Cancer (PPC)
Sponsor: Bristol-Myers Squibb Company
Enrolling: Female Patients Only
IRB Number: AAAU4232
U.S. Govt. ID: NCT05613088
Contact: Reena Vattakalam: / rmv2110@cumc.columbia.edu
Additional Study Information: By doing this study, researchers hope to learn more about the efficacy (how well the drug works) and safety (the drugs side effects) of MORAb-202 (farletuzumab ecteribulin) compared to approved chemotherapy medications in patients with platinum-resistant ovarian cancer. The study will evaluate two doses of MORAb-202. MORAb-202, is made up of two parts; an antibody which targets specific proteins on the cancer cell surface and a chemotherapy drug. The antibody is absorbed into the cell and once inside the chemotherapy drug is released to attack the cancer cell. The treatment being studied, MORAb-202, is investigational, which means its safety and effectiveness have not been established and it is not approved by the United States Food and Drug Administration (FDA) for ovarian cancer. The study chemotherapy medications are approved by the FDA and are standard-of-care treatments for your type of ovarian cancer.
This study is closed
Investigator
June Hou, MD
Do You Qualify?
Have you been diagnosed with Ovarian, Primary Peritoneal (PPC), or Fallopian Cancer? Yes No
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For more information, please contact:
Reena Vattakalam
rmv2110@cumc.columbia.edu