A Phase 1 Basket Study Evaluating the Safety and Feasibility of T Plex, Autologous Customized T Cell Receptor Engineered T Cells Targeting Multiple Peptide/HLAAntigens in Participants with Antigen positive Locally Advanced (Unresectable) or Metastatic Solid Tumors
Sponsor: |
TScan Therapeutics, Inc |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAU7036 |
U.S. Govt. ID: |
NCT05973487 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of the study is to learn if the study treatments TSC-204-A0201, TSC 200-A020, and TSC-204-C0702 alone or in combination, referred to as T-Plex, are safe and effective in treating your type of cancer. T-Plex has not yet been approved by the Food and Drug Administration (FDA). This is a first-in-human study, which means that these products have never been administered to humans before. You are unlikely to benefit from taking part in this study. Cancers include: Colon and Rectal Cancer, Lung Cancer, Cervical Cancer, Ovarian Cancer, Head and Neck/Oral Cancers, Melanoma, and Testicular Cancer.
Investigator
Brian Henick, MD
Are you at least 18 years old? |
Yes |
No |
Have you been diagnosed with an advanced (unresectable) or metastatic solid tumor? |
Yes |
No |