Demonstrate the utility of a portable low-field (64mT) MRI instrument to collect outcome measures in under-served, under-studied populations.
Sponsor: |
Unfunded |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAU9809 |
Contact: |
Donovan Laing: 9299920345 / dal2190@cumc.columbia.edu |
This study aims to use a portable, low-field MRI (magnetic resonance imaging) device to collect important brain data from people with multiple sclerosis (MS) or other neurodegenerative diseaseslike Alzheimer's. The portable MRI device is unique because it is much smaller, less expensive,and can be used in mobile units, which makes it easier to bring medical imaging to people whomay not have easy access to healthcare, such as those living in rural areas or individuals withmobility issues.We plan to scan 450 people who have MS or other related brain conditions. These participants willbe from three different groups: 150 African Americans, 150 Hispanics, and 150 non-Hispanic whiteparticipants. Each person will have their brain scanned using the portable MRI to gatherinformation about brain tissue, volume, and lesions that occur due to MS or similar diseases.Additionally, we will look at how these brain measurements relate to cognitive performancehowwell people perform on memory and thinking testsand see if this relationship holds true with thelower-power MRI device.This project is significant because it will provide reference data from minority populations, who areoften under-represented in clinical research. By using this mobile, accessible MRI technology, wehope to gather data that will help design larger future studies and bring medical imaging tounderserved communities. The data collected from this study will also help scientists betterunderstand how to use portable MRI devices in research and treatment settings forneurodegenerative diseases, making these advanced technologies more accessible for everyone
This study is closed
Investigator
Philip De Jager, PhD
Have you been diagnosed with MS or an inflammatory CNS syndrome? |
Yes |
No |
Do you have a first-degree relative (parent, sibling, child) who has been diagnosed with MS or an inflammatory CNS syndrome? |
Yes |
No |