Additional Study Information: The purpose of this research is to determine the safety and efficacy of investigational study drugquemliclustat (also known as AB680) in combination with chemotherapy gemcitabine and nab-paclitaxel (Gem-NP), compared to a placebo (saline solution not containing treatment drug) in combination with chemotherapy gemcitabine and nab-paclitaxel at treating participants with the type of cancer you have. Quemliclustat has not been approved by the Food and Drug Administration (FDA). Gemcitabine and nab-paclitaxel (Gem-NP) is FDA approved but not in combination with quemliclustat. This is a double-blinded study. This means neither you, the study doctor, nor the study team will know whether you are receiving quemliclustat with Gem-NP or placebo with Gem-NP.