A Phase 1a/1b Study of LY4052031, an Antibody-Drug Conjugate Targeting Nectin-4, in Participants with Advanced or Metastatic Urothelial Carcinoma or Other Solid Tumors
Sponsor: |
Loxo Oncology |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAV3045 |
U.S. Govt. ID: |
NCT06465069 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of this study is to determine whether using LY4052031 in a type of cancer that may have tumor cells that express a protein called Nectin-4 is safe and how well the cancer responds to the study drug. LY4052031 has not been approved by the US Food and Drug Administration (FDA). This is a first in human study and all of the risks are not fully known yet.
Investigator
Alexander Wei, MD
Are you 18 years or older? |
Yes |
No |
Do you have uncontrolled diabetes? |
Yes |
No |