Additional Study Information: We are doing this study to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication. This is an FDA approved device. Involvement in the study is expected to last approximately 60 months. Patients will be asked to collect blood pressure (BP) at home, to help us understand how ultrasound renal denervation impacts their blood pressure over time. Patients will receive home BP monitor device for the entire duration of the study and will be trained how to use it.