Effects of Bariatric Surgery on Salivary and Gut Microbiota in Children with Obesity: Associations with Liver Function and Lipid Metabolism
| Sponsor: |
Unfunded |
| Enrolling: |
Male and Female Patients |
| Study Length: |
6 Months |
| Clinic Visits: |
2 |
| IRB Number: |
AAAV5616 |
| Contact: |
Hidenori Moriyama, MD: 9296873897 / hm3050@cumc.columbia.edu |
Bariatric surgery and a once-weekly glucagon-like peptide-1 medicine both cause major weight loss in teens, but their effects on mouth and gut bacteria and on damaged blood fats tied to metabolism are still unknown. This study will collect saliva, stool, and routine blood samples from adolescents before treatment and six months later to see how these biological markers change and whether the shifts accompany better liver-enzyme and cholesterol results.
Investigator
Ilene Fennoy, MD
| Are you between 13 and 18 years old? |
Yes |
No |
| Are you scheduled to have weight-loss surgery or to start treatment with a medication for weight management? |
Yes |
No |
| Are you willing to provide saliva and stool samples for this research? |
Yes |
No |