Role of Insulin Action in Psoriasis Pathogenesis
Insulin Action in Psoriasis
Sponsor: Internal
Enrolling: Male and Female Patients
Study Length: 1 Days
Clinic Visits: 1
IRB Number: AAAU4674
U.S. Govt. ID: NCT06242847
Contact: Ishwari Nagnur: 2123059336 / imn2113@cumc.columbia.edu
Additional Study Information: We are conducting a research study on how psoriasis might be caused or worsened by high levels of the blood sugar-lowering hormone insulin. We are seeking people with plaque psoriasis, ages 18-65, who are overweight or obese with a body mass index of 25-35. Participants will have blood drawn and small skin biopsies taken from psoriasis plaques and nearby healthy skin before and after drinking a sugary beverage (total of 4 biopsies). We will use these specimens to determine if there is too much insulin activity in the psoriatic skin. The study takes place on a single morning, over 3-4 hours and participants will receive free transportation by car service or reimbursement for transportation expenses.
Investigator
Joshua Cook, MD, PhD
Do You Qualify?
Do you have plaque psoriasis? Yes No
Will you be able to attend a 3-4-hour study visit? Yes No
Are you okay with having four skin biopsies taken and blood drawn? Yes No
Do you have known bleeding problems or take medications that prevent blood clots? Yes No
Do you have any history of diabetes? Yes No
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For more information, please contact:
Ishwari Nagnur
imn2113@cumc.columbia.edu
2123059336