A Phase II Randomized Multicenter Placebo-Controlled Blinded Study of Sorafenib Adjuvant Therapy in High Risk Orthotopic Liver Transplant (OLT) Recipients with Hepatocellular Carcinoma (HCC)
A study for subjects with liver cancer using a drug to prevent recurrence of liver cancer following liver transplantation
Sponsor: University of California Los Angeles & Bayer Health
Enrolling: Male and Female Patients
Study Length: 24 Months
Clinic Visits: 17
IRB Number: AAAK6255
Contact: Theresa Lukose: 212-305-3839 / tt2103@columbia.edu
Additional Study Information: The purpose of this study is to determine if Nexavar (sorafenib), the study medication, is effective in preventing cancer recurrence in high risk patients following liver transplantation. The purpose of this study is to determine if sorafenib is a safe and effective treatment option for preventing the recurrence of liver cancer in high risk subjects following liver transplantation. Study participants will be randomly assigned to a group that either receives sorafenib or a placebo (a pill that doesnt have any drugs or medicine). Every study visit will require a blood draw and a physical examination.
This study is closed
Investigator
Tomoaki Kato, MD
Do You Qualify?
Are you a recent liver transplant recipient? Yes No
Do you have HCC? (Hepatocellular carcinoma) Yes No
Have you experienced transplant rejection? Yes No
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Place Holder




For more information, please contact:
Theresa Lukose
tt2103@columbia.edu
212-305-3839