Prospective Randomized Double Blind Placebo Controlled Trial of Rifaximin 550mg PO Twice Daily for Three Months to Prevent Recurrent Fibrosis in Liver Transplant Recipients with Chronic Hepatitis C Virus Infection
Sponsor: |
Robert Brown |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAI4155 |
U.S. Govt. ID: |
NCT01603108 |
Contact: |
Theresa Lukose: 212-305-3839 / tt2103@columbia.edu |
The purpose of this study is to determine if the administration of non-absorbable antibiotics (rifaximin) for the first three months after liver transplant period will reduce the amount of fibrosis (scarring of the liver) in liver transplant patients with hepatitis C virus (HCV) by lowering serum LPS (a protein in the blood that comes from the bacteria in your intestines and may cause scarring in the liver). Participants will be assigned to receive rifaximin (a tablet) or a placebo (does not contact active study medication) twice daily every day for 3 months post liver transplant.
This study is closed
Investigator
Robert Brown, MD, MPH
Do you have HCV? |
Yes |
No |
Are you listed for liver transplantation or have received a liver transplant within the past 10 days? |
Yes |
No |