ACTH, Pro-opiomelanacortin Peptide and AGRP Secretion in Patients with Cushing's Syndrome and Silent Corticotrophs
Using New Tumor Markers in Blood (POMC, ACTH, and AgRP) to Diagnose and Track Cushing's Syndrome and Other Neuroendocrine Tumors
Sponsor: NIH
Enrolling: Male and Female Patients
IRB Number: AAAI8604
Contact: Amanda Tsang: 212-305-0486 / at2695@cumc.columbia.edu
Additional Study Information: The purpose of this study is to determine if measuring blood levels of proteins called POMC, AgRP, and chromogrannin A (CGA) can be used to diagnose and track tumor growth and recurrence in patients that have ACTH-dependent Cushing's syndrome, non-secreting pituitary tumors, and other neuroendocrine tumors. We invite you to participate if you have: a.) ACTH-dependent Cushings Syndrome, b.) a non-secreting pituitary tumor, c.) a pheochromocytoma, d.) high ACTH levels (hypercorticotropinemia), or e.) other neuroendocrine tumors. Our study procedure involves drawing an extra tube of blood when you are scheduled to follow-up with your doctor at Columbia Medical Center and need to have routine blood labs taken. If you participate, one additional 15cc (1 tablespoon) sample of blood will be collected whenever you have routine blood labs taken. In addition, we will ask you to complete a short questionnaire about your symptoms, mood, and quality of life and may also ask you to complete at-home salivary cortisol tests.
This study is closed
Do You Qualify?
Have you been diagnosed with ACTH-dependent Cushings Syndrome, pituitary tumor, or other neuroendocrine tumor? Yes No
Are you currently a patient at Columbia Medical Center or Presbyterian Hospital? Yes No
Are you over the age of 18? Yes No
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For more information, please contact:
Amanda Tsang
at2695@cumc.columbia.edu
212-305-0486