A Phase II, Randomized, Open-Label, Multi-Center, Global Study of MEDI4736 Monotherapy, Tremelimumab Monotherapy, and MEDI4736 in Combination with Tremelimumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Sponsor: |
AstraZeneca |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAO5153 |
U.S. Govt. ID: |
NCT02319044 |
Contact: |
Ryan Shelton: 212-304-5485 / rs3323@columbia.edu |
The purpose of this study is to determine the effectiveness and safety of study drug MEDI4736 monotherapy, tremelimumab monotherapy, and MEDI4736 and tremelimumab combination therapy in the treatment of patients with recurrent or metastatic PD-L1-negative squamous cell carcinoma of the head and neck who have progressed during or after treatment with platinum-containing regimen for recurrent or metastatic disease.
This study is closed
Investigator
Sewanti Limaye, MD
Do you have at least one lesion? |
Yes |
No |
Have you had prior exposure to immune-mediated therapy? |
Yes |
No |