Open-Label, Dose-Escalation Trial to Evaluate the Safety,Pharmacokinetics, and Pharmacodynamics of Daily Oral MGCD265 Administered Without Interruption to Patients with Advanced Malignancies
Sponsor: |
Mirati Therapeutics Inc. |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAP0559 |
U.S. Govt. ID: |
NCT00697632 |
Contact: |
Victoria Vulaj: 646-317-6041 / vv2218@columbia.edu |
The goal of this clinical research study is to find the highest safe dose of the drug MGCD265 thatcan be given to patients with advanced cancer. The safety of this drug, and the effect that it hason your disease and your body will also be studied.MGCD265 is a drug that works by blocking proteins that are important for cancer cells to grow.MGCD265 also prevents the growth of new blood vessels that help cancer tumors grow andspread. MGCD265 an investigational agent. This means that MGCD265 is not approved by theFood and Drug Administration (FDA).
This study is closed
Investigator
Richard Carvajal, MD
Do you have an advanced cancer that is currently incurable with standard therapy? |
Yes |
No |