Additional Study Information: This research study is testing an investigational medication called AMG 714 for people with refractory celiac disease Type II. If youre at least 18 years of age, diagnosed with celiac disease, and you are still experiencing persistent or recurrent intestinal atrophy and gastrointestinal symptoms despite following a strict gluten-free diet for at least 6 12 months, then you may qualify to participate in this study and receive at no cost: Study medication (active drug or placebo) for refractory celiac disease Type II and study-related care and monitoring. To qualify, you must be adhering to a strict gluten-free diet for at least 6 months prior to enrollment and must continue to follow the gluten-free diet throughout the study.