A Multi-center Randomized Phase II Study of the Impact of CD34+ Cell Dose on Progression-free Survival Following High-Dose Therapy and Autologous Stem Cell Transplantation for Relapse and Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Sponsor: |
Memorial Sloan Kettering Cancer Center |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAQ8451 |
U.S. Govt. ID: |
NCT02570542 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of this study is to study the impact of stem cell dose on outcome after autologous transplant. An autologous transplant is infusion of your own bone marrow cells (stem cells) following a high-dose of chemotherapy. Autologous transplant is the standard treatment for relapsed Diffuse Large B-Cell Lymphoma (DLBCL) or DLBCL that did not respond to initial chemotherapy. The treatment is meant to keep your lymphoma from coming back. Previous studies have suggested that the amount of your stem cells that you get at transplant may effect outcomes. This has not been proven in a randomized study.
This study is closed
Investigator
Markus Mapara, MD
Have you been diagnosed with Diffuse Large B-Cell Lymphoma that has come back or is resistant to treatment? |
Yes |
No |