A phase 1, open-label, dose-escalation study to evaluate the safety and tolerability of SGN-LIV1A in patients with LIV-1-positive metastatic breast cancer
Sponsor: |
Seattle Genetics, Inc |
Enrolling: |
Female Patients Only |
IRB Number: |
AAAQ9893 |
U.S. Govt. ID: |
NCT01969643 |
Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of this study is to find out what side effects (unwanted effects) are caused in patients with breast cancer who are given SGN-LIV1A (single therapy). This study will also look at other effects of SGN-LIV1A, including its effect on this type of cancer. This study is also being done to find out what side effects (unwanted effects) are caused in patients with HER2-positive breast cancer who are given SGN-LIV1A in combination with trastuzumab (combination therapy). SGN-LIV1A has been given to animals, but has never been given to humans before this study.
This study is closed
Investigator
Kevin Kalinsky, MD, MS
Have you been diagnosed with breast cancer? |
Yes |
No |