A phase 1, open-label, dose-escalation study to evaluate the safety and tolerability of SGN-LIV1A in patients with LIV-1-positive metastatic breast cancer
| Sponsor: |
Seattle Genetics, Inc |
| Enrolling: |
Female Patients Only |
| IRB Number: |
AAAQ9893 |
| U.S. Govt. ID: |
NCT01969643 |
| Contact: |
Research Nurse Navigator: 212-342-5162 / cancerclinicaltrials@cumc.columbia.edu |
The purpose of this study is to find out what side effects (unwanted effects) are caused in patients with breast cancer who are given SGN-LIV1A (single therapy). This study will also look at other effects of SGN-LIV1A, including its effect on this type of cancer. This study is also being done to find out what side effects (unwanted effects) are caused in patients with HER2-positive breast cancer who are given SGN-LIV1A in combination with trastuzumab (combination therapy). SGN-LIV1A has been given to animals, but has never been given to humans before this study.
This study is closed
Investigator
Kevin Kalinsky, MD, MS
| Have you been diagnosed with breast cancer? |
Yes |
No |