Dr. David Pagliaccio received his PhD in neuroscience from Washington University in St. Louis. His graduate work with Drs. Deanna Barch and Joan Luby focused on the effects of stress and stress-system genes on brain structure and function in children with early-onset depression. During his postdoctoral fellowship with Drs. Daniel Pine and Ellen Leibenluft, Dr. Pagliaccio continued fMRI research to examine the neural underpinnings of pediatric anxiety and irritability. His research aims are to use neuroimaging and other methods to understand the mechanisms underlying psychiatric disorders in youth, particularly affective psychopathology, as well as to assess the psychometrics and reliability of currently used research methods. With his collaborators at the Columbia University Irving Medical Center/New York State Psychiatric Institute, Dr. Pagliaccio is exploring alterations in brain circuitry and functioning relating to affective disorders, OCD, learning disorders, and other pediatric pathologies.