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Displaying 1 - 17 of 17

Study of IW-3300 in Patients with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

Condition: Urology
Investigator: Svjetlana Lozo, MD, MPH
Status: Closed
The purpose of this study is to find out if IW-3300, an investigational new drug, helps bladder pain when given as a rectal (inserted into the anus) foam. The study will test IW-3300. IW-3300 is a new drug that has been developed for treating people like you with interstitial cystitis/bladder pain syndrome. It is not yet approved by the United States Food…
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A study for patients with Cystic Fibrosis using study drug VX-661 in combination with Ivacaftor

Condition: Lung Disease / Cystic Fibrosis
Investigator: Claire Keating, MD
Status: Closed
This study is being done to learn more about the safety and effectiveness of study drug VX-661 in combination with ivacaftor in patients aged 12 years and older with Cystic Fibrosis (CF). In this Study there are two treatment groups. If the patient meets all the rules for being in the Study, they willbe in one of the two treatment groups. The patient will…
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Acute treatment of Migraine using the Cefaly device

Condition: Headaches / Migraines
Investigator: Denise Chou, MD
Status: Closed
This study plans to learn more about a device called the Cefaly and if it is effective for treating migraine attacks. This device is approved by the Food and Drug Administration (FDA) for the prevention of episodic migraines, but clinical data has not yet been collected on its effectiveness in treating migraine attacks. The Cefaly device works by generating…
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Validation of electronic (web-based and smartphone) administration of measures of pelvic floor dysfunction

Condition: Urology
Investigator: Doreen Eleanor Chung, MD
Status: Closed
You will be randomly assigned to complete questionnaires via either a paper format, web-based format, or smartphone format. About 2 weeks later but before treatment begins, you will be asked to complete a different form of the questionnaire either in the office or at home. You will be emailed and/or called by research staff to remind you to complete the…
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A study for subjects with non-cystic fibrosis bronchiectasis (NCFB) using study drug Pulmaquin to manage chronic lung infections

Condition: Lung Disease / Cystic Fibrosis
Investigator: Emily DiMango, MD
Status: Closed
The purpose of this study is to assess how effective the study drug Pulmaquin is in the management of chronic lung infections with Pseudomonas aeruginosa in subjects with non cystic fibrosis (nonCF) bronchiectasis by evaluating the time to first pulmonary exacerbation. A pulmonary exacerbation is defined as the new appearance or worsening in 4 or more of…
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ENFORCE STUDY: A study for patients with episodic cluster headaches using study drug TEV-48125 (Fremanezumab)

Condition: Headaches
Investigator: Marianna Shnayderman Yugrakh, MD
Status: Closed
The ENFORCE Teva Cluster Headache clinical trial is looking for people who have been diagnosed with episodic cluster headaches to participate. People who volunteer and qualify may have the opportunity to try an investigational study drug for cluster headaches. If you're 18 to 70 years old and have experienced cluster headaches for 12 months or more,…
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A study for patients with cystic fibrosis using study drug ataluren (PTC124)

Condition: Lung Disease / Cystic Fibrosis
Investigator: Emily DiMango, MD
Status: Closed
The purpose of this study is to find out whether the study drug altaluren can help lung function and can reduce the symptoms associated with cystic fibrosis (CF), and decrease the number of hospitalizations and the use of antibiotics for CF-related lung infections. The study will also investigate whether the drug can help improve overall patient quality of…
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A study for patients with Cystic Fibrosis using study drug VX-440

Condition: Lung Disease / Cystic Fibrosis
Investigator: Claire Keating, MD
Status: Closed
This study is being done to learn more about the safety and effectiveness of VX-440 used in combination with tezacaftor and ivacaftor in patients with cystic fibrosis. VX-440 given in combination with tezacaftor and ivacaftor is an investigational drug; investigational means the drug is not approved by the Food and Drug Administration (FDA), and is still…
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A study for patients with Cystic Fibrosis using study drug VX-440

Condition: Lung Disease / Cystic Fibrosis
Investigator: Claire Keating, MD
Status: Closed
The purpose of the ELEVATE CF study is to evaluate an oral investigational medication called VX-440 tosee if it is safe, effective, and well-tolerated when taken alone or with two other oral medications(VX-661 tezacaftor and ivacaftor) in people with cystic fibrosis (CF). This triple combination(TC) is being tested to see if it improves chloride transport (…
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A study for patients with Cystic Fibrosis using study drug VX-661

Condition: Lung Disease / Cystic Fibrosis
Investigator: Emily DiMango, MD
Status: Closed
This study is being done to learn more about the safety and effects of the combination of VX-661 and ivacaftor in subjects with Cystic Fibrosis (CF).
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A study for patients with trigeminal neuralgia (TN) pain using carbon dioxide for pain relief

Condition: Headaches
Investigator: Denise Chou, MD
Status: Closed
If so, you may be able to take part in a clinical research study. This study is being done to see how wellcarbon dioxide (CO2) may provide relief from the pain associated with Trigeminal Neuralgia (TN). CO2 is a gas that is part of the air we breathe and is used to make bubbles in carbonated drinks. The screening and treatment office visit can be done in…
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A study for patients with bladder cancer using the Cysview and blue light system to detect tumors in order to prevent reoccurence

Condition: Urology
Investigator: Joel DeCastro, MD, MPH
Status: Closed
The purpose of the study is to investigate if Cysview and blue light is better than white light in detecting tumors in individuals with bladder cancer prior to and during surgery that are in follow-up for tumor recurrence. Cysview is an FDA approved drug that is used in combination with a lamp from KARL STORZ to detect tumors in the bladder (KARL STORZ D-…
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A study for patients with Cystic Fibrosis using oral study drug CTX-4430

Condition: Lung Disease / Cystic Fibrosis
Investigator: Emily DiMango, MD
Status: Closed
The main purpose of this study is to look at the effectiveness, safety, and tolerability of study drug CTX-4430 when compared to a placebo (sugar pill) taken once-daily for 48 Weeks in adult patients with CysticFibrosis (CF).
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A study for patients with episodic or chronic migraine using the Cefaly device for the acute treatment of migraine headaches

Condition: Headaches / Migraines
Investigator: Denise Chou, MD
Status: Closed
This study plans to learn more about a device called the Cefaly and if it is effective for treating migraine attacks. This device is approved by the Food and Drug Administration(FDA) for the prevention of episodic migraines, but clinical data has not yet been collected on its effectiveness in treating migraine attacks.
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A registry for patients with Overactive Bladder (OAB)

Condition: Urology
Investigator: Matthew Rutman, MD
Status: Closed
This study is for adults with Overactive Bladder. The purpose of this registry is to collect information about patients who have Overactive Bladder (OAB) and who are receiving either mirabegron or another approved antimuscarinic medication (single drug). To collect this information, the study Sponsor has created a research registry. A registry is a kind of…
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An study for patients with cystic fibrosis (CF) treated with TOBI Podhaler or other FDA approved inhaled antipseudomonal antibacterial drug

Condition: Lung Disease / Cystic Fibrosis
Investigator: Hossein Sadeghi, MD
Status: Closed
This study is for patients who have been prescribed tobramycin inhalation powder (TOBI Podhaler) or another inhaled medication used to treat cystic fibrosis patients whose lungs contain bacteria called Pseudomonas aeruginosa. The purpose of this research study is to assess how well TOBI Podhaler works on treating Pseudomonas aeruginosa in the lungs of…
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A study to reduce episodic and/or chronic migraine headache symptoms in patients who have a common heart defect called Patent Foramen Ovale

Condition: Headaches / Migraines
Investigator: Robert Sommer, MD
Status: Closed
This study is for patients who have severe migraine headaches that might be a result of a hole in the heart wall called a Patent Foreman Ovale, or PFO. It is known that as many as 40% of patients with migraine headaches also have a PFO. It is not well understood how the two are related, or how having a hole in the heart wall could cause headaches. In this…
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