233 Studies Now Enrolling
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Displaying 1 - 7 of 7
Condition: Cancer / Brain Cancer
Investigator: Mikhail Doubrovin, MD
Status: Closed
The purpose of the study is to evaluate the safety of Lutathera alone in patients with recurrent glioblastoma and the combination of Lutathera with radiotherapy with temozolomide (TMZ) in patients with newly diagnosed glioblastoma (GB) and to establish the appropriate dose of this combination. Lutathera is a radioligand therapy, which is a targeted…
Condition: Cancer / Multiple Myeloma
Investigator: Divaya Bhutani, MD
Status: Closed
The purpose of this study is to see how teclistamab by itself compares to study treatment combinations that are commonly used to treat multiple myeloma. These study treatment combinations are either pomalidomide, bortezomib and dexamethasone (called PVd) or carfilzomib and dexamethasone (called Kd). The patients will be randomly assigned to one of the study…
Condition: Cancer / Brain Cancer
Investigator: Stergios Zacharoulis, MD
Status: Closed
Children and young adults with diffuse midline glioma will be treated with Focused Ultrasound (FUS) with DEFINITY microbubbles and neuro-navigator-controlled sonication. The overall goal of this study is to see if the study treatment plan will improve the outcome of participants with diffuse midline glioma, for which no known cure exists, and determine…
Condition: Cancer / Brain Cancer
Investigator: James Hinkley Garvin Jr, MD
Status: Closed
The purpose of this study is to find the best dose of a drug called MTX110 and a contrast agent called gadolinium that can be given safely in children with newly diagnosed diffuse midline gliomas, which is a kind of brain tumor. All patients enrolled in the study will receive infusion of MTX110 and Gadolinium delivered with a pump directly into the tumor…
Condition: Healthy Volunteers / Exercise
Investigator: Richard Sloan, PhD
Status: Closed
This study focuses on the effects of aerobic conditioning on cognition and brain activity. Eligible participants will complete an exercise stress test, MRI, and cognitive testing session at the beginning and end of the study. Once participants complete the first set of appointments, they will be randomly assigned to one of two conditions for 12-weeks.…
Condition: Healthy Volunteers / Exercise
Investigator: Richard Sloan, PhD
Status: Closed
This study focuses on the effects of aerobic conditioning on cardiovascular function and inflammatory response. Eligible participants will complete an exercise stress test, laboratory visit, and cognitive testing session at three specific time points over the course of the study. Once the initial set of appointments is complete, participants are randomly…
Condition: Cancer / Multiple Myeloma
Investigator: Suzanne Lentzsch, MD
Status: Closed
We are doing this study to learn if the MMprofiler test can help your doctor in making decisions about your treatment. The MMprofiler genomic test will look at a large number of normal genes. The test will predict risk of your multiple myeloma (MM) by assessing whether these genes are turned on or off in your cancer cells. The purpose of this research is to…