The purpose of this research study is to determine whether rosuvastatin is safe and can help people living with cirrhosis lead longer, healthier lives. The study drug, rosuvastatin, is investigational, meaning it has not yet been approved for market use for this disease condition by the United States Food and Drug Administration (FDA). Participants will…
In this study, we will collect information from the medical record of pediatric livertransplant recipients who received live vaccines as part of their routine post-transplant care. This data will be combined with data from other centers across the United States and…
The purpose of the study is to collect scientific data on pediatric livertransplantation to learn more about how children do after livertransplant. Collecting these data is expected to help researchers learn more about…
The social determinants of health have a large impact on health. We have previously demonstrated that an index of neighborhood socioeconomic deprivation was associated with an increased risk of medication non-adherence in children after livertransplant and an increased risk of graft failure and…
LCN Cohort Study is an observational study designed to identify risk factors and develop prediction models for risk of decompensation in adults with liver cirrhosis. LCN Cohort Study involves multiple institutions and an anticipated 1200 participants. Enrolled participants will have study visits every 6 months for a total of 3…
In this research, we want to learn more about how to improve care for children who are listed for or who have received a livertransplant. The goal of this research is to look at how different hospitals treat these children and to look at their outcomes to help improve care, decrease…
TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three-arm clinical trial of immunosuppressive therapy for children with acute liver failure. This is a double-blind study, so the study doctors and participants will not know to which arm the participants are assigned. The study will determine if…