A Phase 1 Multiple Ascending Dose Study Of DS-3032b, An Oral MDM2 Inhibitor, In Subjects With Advanced Solid Tumors Or Lymphomas
Sponsor: |
Daiichi Sankyo Pharma Development |
Enrolling: |
Male and Female Patients |
IRB Number: |
AAAN4003 |
U.S. Govt. ID: |
NCT01877382 |
Contact: |
Gary Schwartz, MD: 646-317-6041 / gks2123@cumc.columbia.edu |
The purpose of this study is to find the highest dose and the best schedule of the study drug, DS-3032b, that can be given safely in subjects with advanced solid tumors and for subjects that did not respond or no longer respond to standard therapy. DS-3032b works against cancer by blocking the activity of a protein called MDM2. DS-3032b works against cancer by blocking the activity of a protein called MDM2.
This study is closed
Investigator
Gary Schwartz, MD
Do you have an advanced solid tumor that is not responding well to standard treatment? |
Yes |
No |
Are you able to take oral medication? |
Yes |
No |
Are you free of any active infection that would interfere with therapy? |
Yes |
No |