Association of genetic variations and weight loss response to naltrexone/bupropion
		
	
		
			
				| Sponsor: | National Institute of Diabetes and Digestive and Kidney Diseases | 
			
			
				| Enrolling: | Male and Female Patients | 
							
					| Study Length: | 40 Weeks | 
						
							
					| Clinic Visits: | 6 | 
			
			
                            
                    | IRB Number: | AAAU3131 | 
            
			 
				
					| U.S. Govt. ID: | NCT05919797 | 
					
			
				| Contact: | Sarah Borden: 212-305-4006 / weightlossstudy@cumc.columbia.edu | 
		
	
		The purpose of this study is to evaluate if genetic variations are associated with the amount of weight loss with diet and while taking an FDA-approved medication for weight loss. The participation lasts ten months and includes six in-person visits at CUIMC with blood sampling and questionnaires, virtual nutritional counseling, and taking an oral weight loss medication for 28 weeks.
	
	
	   	
		Investigator
		
		Judith Korner, MD
		
							
			   
	
		
		
		
			
				
					| Are you between the ages of 18 and 65? | Yes | No | 
				
									
						| Do you have diabetes? | Yes | No | 
								
									
						| Do you have a history of previous bariatric surgery? | Yes | No | 
				
									
						| Do you have obesity or are you overweight? | Yes | No | 
				
									
						| Do you live in the New York City tristate area (NY, NJ, CT)? | Yes | No |