Glutamatergic Mechanisms of Psychosis and Target Engagement: Aim2
Brain Imaging Study w/ Ketamine for Healthy Volunteers
Sponsor: NIMH
Enrolling: Male and Female Patients
IRB Number: 8299
U.S. Govt. ID: NCT05401227
Contact: Kate Mills, RA: 6467748496 / katelyn.mills@nyspi.columbia.edu
Additional Study Information: We are recruiting volunteers aged 18-55 for a research study determining how an FDA approved medication called Cobenfy affects brain chemicals and brain activity in healthy adults. To do this, participants receive either the study medication or a placebo, along with a low, medium, or high dose of ketamine, which is used in a controlled research setting, to temporarily affect glutamate signaling in the brain. Throughout the study, participants undergo MRI scans so researchers can measure how the medication changes brain activity and brain chemistry. Participation lasts about 4 to 6 weeks, and compensation is up to $2000 if all components of the study are completed.
This study is closed
Investigator
Joshua Kantrowitz, Md
Do You Qualify?
Are you 18-55 years old? Yes No
Have you ever been diagnosed with a psychiatric disorder (depression, anxiety, etc.)? Yes No
Do you have any first-degree relatives with schizophrenia or another psychotic disorder? Yes No
Is there any reason you should NOT have an MRI? Yes No
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You may be eligible for this study

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For more information, please contact:
Kate Mills, RA
katelyn.mills@nyspi.columbia.edu
6467748496