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  • Show all (26)
  • (-) Currently Recruiting (6)
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  • Show all (15)
  • (-) Cancer (6)
    • Brain Cancer (1)
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    • Pancreatic Cancer (2)
    • Skin Cancer (1)
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Displaying 1 - 6 of 6

Comparing Investigational Surgery to Laparotomy After Chemotherapy in Women with Epithelial Ovarian Cancer (EOC)

Condition: Cancer / Gynecologic Cancer
Investigator: Jason Wright, MD
Status: Currently Recruiting
The goal of this clinical research study is to compare the outcomes of minimally invasive surgery (the investigational surgery) to laparotomy (the current standard of care) in women with Epithelial Ovarian Cancer (EOC) who receive chemotherapy before and after surgery…
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Study of Zimberelimab in Patients with Advanced Pancreatic Cancer who are Eligible for Surgery

Condition: Cancer / Pancreatic Cancer
Investigator: Gulam Manji, MD, PhD
Status: Currently Recruiting
The main goal of this study is to find out if treatment with zimberelimab and stereotactic body radiation therapy alone or in combination with quemliclustat, with or without etrumadenant, given before surgery is safe and if it can further increase the immune response against the tumor.
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OptimICE-PCR: Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer

Condition: Cancer / Breast Cancer
Investigator: Meghna Trivedi, MD
Status: Currently Recruiting
This study is being done to answer the following question: Among patients with early-stage triple-negative breast cancer (TNBC) who achieve a pathologic complete response (pCR) after preoperative chemotherapy in combination with pembrolizumab, will observation after surgery be as effective as completing 6 more months of…
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Study of V940 Plus Pembrolizumab in Patients With High-Risk Melanoma

Condition: Skin Cancer / Melanoma
Investigator: Benjamin Izar, MD
Status: Currently Recruiting
The purpose of this study is to compare V940 plus pembro given after surgery to a placebo plus pembro given after surgery and to study how effective the study drug is. A placebo looks like a study drug, but it has no active ingredients. V940 has not yet been approved by the Food and Drug…
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Study of Bethanechol in Combination with Chemotherapy for Patients with Pancreatic Cancer

Condition: Cancer / Pancreatic Cancer
Investigator: Susan Bates, MD
Status: Currently Recruiting
The purpose of this study is to determine whether the drug, bethanechol, could potentially be used in combination with chemotherapy regimen gemcitabine and nab-paclitaxel and surgery to decrease the chance of the cancer coming back after it is removed. Animal models have shown that treatment with bethanechol can inhibit cancer…
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Study of Sonocloud 9 in Patients with Glioblastoma (GBM)

Condition: Cancer / Brain Cancer
Investigator: Brian Gill, MD
Status: Currently Recruiting
The purpose of this study is to see if the implantable device, Sonocloud 9, is effective getting chemotherapy to better reach your tumor compared to receiving standard-of-care chemotherapy Temozolomide and Lomustine and to see how safe and tolerable the device is. Sonocloud 9 works by making the blood-brain barrier (BBB) more permeable (allowing liquids or…
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