We are recruiting adults with bipolar disorder, and adults with no psychiatric disorder, ages 18-60 years. As a participant in our study, you will be asked to attend one remote or in-person visit and one to two in-person visits. The following procedures will occur: Visit 1 (1 - 2.5 hrs): Clinical interview for overall psychiatric history as well as current…
We will evaluate the D-cycloserine (DCS) and lurasidone with MRI measurement of brain responses to DCS. DCS is a drug that works on the same brain receptor as ketamine. DCS is not approved by the FDA for bipolar depression. Study participants will receive a dose of lurasidone or placebo in one MRI and a dose of DCS in another, followed by an optional follow…
This research study is being done to understand how CPAP for sleep apnea may affect hypertensive disorders of pregnancy and other complications of pregnancy such as gestational diabetes. The purpose of the home sleep test is to find women with sleep apnea. Sleep apnea is when you have one or more pauses in breathing or shallow…