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The Cancer of the Pancreas Screening-5 Study (CAPS5 Study)

Condition: Cancer / Pancreatic Cancer

Status: Currently Recruiting

Pancreatic cancer is a deadly disease and the best hope for improving the chances of survival is to find it early. Some patients, called "high risk", have an inherited predisposition to pancreatic cancer. Certain medical centers have started programs where "high risk patients" undergo testing, such as receiving imaging scans, to look for…

Study of Multiple Treatment Combinations in Patients with Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)

Condition: Cancer / Pancreatic Cancer

Investigator: Gulam Manji, MD, PhD

Status: Closed

The purpose of this study is to learn which treatment works best in patients with pancreatic cancer. The study explores multiple treatment combinations. A study drug called atezolizumab may be combined with other drugs such as cobimetinib, PEGPH20, and BL-8040. Patients may also be assigned to receive standard chemotherapy treatment.

A study for patients with episodic or chronic migraine using the Cefaly device for the acute treatment of migraine headaches

Condition: Headaches / Migraines

Investigator: Denise Chou, MD

Status: Closed

This study plans to learn more about a device called the Cefaly and if it is effective for treating migraine attacks. This device is approved by the Food and Drug Administration(FDA) for the prevention of episodic migraines, but clinical data has not yet been collected on its effectiveness in treating migraine attacks.

Rituximab for Systemic Sclerosis Associated Pulmonary Arterial Hypertension (SSc-PAH)

Condition: Lung Disease / Pulmonary Hypertension

Investigator: Elana Bernstein, MD

Status: Closed

This study involves two infusions of either rituximab or placebo, two right heart catheterizations (6 months apart), and a variety of other clinical study procedures and exams.

A study to reduce episodic and/or chronic migraine headache symptoms in patients who have a common heart defect called Patent Foramen Ovale

Condition: Headaches / Migraines

Investigator: Robert Sommer, MD

Status: Closed

This study is for patients who have severe migraine headaches that might be a result of a hole in the heart wall called a Patent Foreman Ovale, or PFO. It is known that as many as 40% of patients with migraine headaches also have a PFO. It is not well understood how the two are related, or how having a hole in the heart wall could cause headaches. In this…

Acute treatment of Migraine using the Cefaly device

Condition: Headaches / Migraines

Investigator: Denise Chou, MD

Status: Closed

This study plans to learn more about a device called the Cefaly and if it is effective for treating migraine attacks. This device is approved by the Food and Drug Administration (FDA) for the prevention of episodic migraines, but clinical data has not yet been collected on its effectiveness in treating migraine attacks. The Cefaly device works by generating…

A study for patients with pulmonary hypertension using study drug Riociguat

Condition: Lung Disease / Pulmonary Hypertension

Investigator: David Lederer, MD

Status: Closed

The purpose of this study is to study the effects of a new study drug known as Riociguat in people diagnosed with pulmonary hypertension (PH) associated with idiopathic interstitial pneumonia (IIP). Patients will be in the study for approximately 26 weeks in which they will take the pill Riogciguat three times a day.

Investigation of an ultrasound device for pulmonary artery denervation in patients with pulmonary hypertension.

Condition: Lung Disease / Pulmonary Hypertension

Investigator: Erika Berman-Rosenzweig, MD

Status: Closed

This is a clinical research study designed to determine the safety and effectiveness of the TIVUS system, an investigational device used in the treatment of PAH. The TIVUS System is intended to treat patients with pulmonary artery hypertension by injuring the sympathetic nerves surrounding the pulmonary vasculature (denervation) using ultrasonic energy. The…

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