During pregnancy, a baby's heart rate can tell us a lot about how their brain and body develop. Our team is testing a new, easy-to-use device that you can wear at home to track the baby's heartbeat for up to 24 hours. By using the monitor in your everyday environment, we can learn more about your baby's development in a natural setting,…
The Lugo Lab at Columbia University's Department of Psychiatry is conducting a study to better understand experiences related to extreme heat during pregnancy and to inform the development of heat preparedness resources for perinatal care. We are recruiting English-speaking participants who are 18 years of age or older and reside in New York State and…
We are conducting a research trial to determine if low dose Aspirin either 81 or 162 mg will prevent preterm birth in patients who have had a previous preterm birth, still birth, or complications of pregnancy including preeclampsia, small for gestational age baby, fetal growth restriction, or placental abruption. You will be randomized to 81 or 162 mg and…
You are invited to participate in a research study to understand how environmental exposures during pregnancy influence the health and development of children. This study will begin at pregnancy and follow your child through age 11. A trained research worker will work with you and your child, administering questionnaires to you and developmental evaluations…
The Lugo Lab at Columbia University's Department of Psychiatry is conducting a study of stress and sleep in childhood and pregnancy, which will take place over the next year. We are recruiting pregnant people who identify as Latinx/Hispanic. You will be compensated for your time! We are flexible in scheduling convenient times for you to come in. The…
Our team is looking at the relationship between a mother and her baby to see how different prenatal and infant experiences affect a baby's brain development. Specifically, we are looking at maternal immune activation (MIA) and how prenatal exposure to MIA can affect a baby's development. For our study, we ask participants to come in for up to 3…
The Center for Intergenerational Psychiatry at Columbia University is recruiting pregnant individuals. We want to learn how feeling worried or anxious (or not having these feelings) may impact pregnant individuals and their babies. We would like to invite people from a wide-range backgrounds who are in between 12 to 34 weeks of their pregnancy to…
We are doing this study to test the use of a drug called bromocriptine for women with a condition called Peripartum cardiomyopathy (PPCM). The study will look at how the heart muscle improves in women taking bromocriptine compared to a group of women given a placebo or inactive pill.
This research study is being done to understand how CPAP for sleep apnea may affect hypertensive disorders of pregnancy and other complications of pregnancy such as gestational diabetes. The purpose of the home sleep test is to find women with sleep apnea. Sleep apnea is when you have one or more pauses in breathing or shallow breaths while you sleep.…
This study will enroll participants who did or did not receive a SARS-CoV-2 vaccine during their pregnancy and have a child who is now 18-30 months of age. In order to assess the long-term outcomes of the offspring of those who received SARS-CoV-2 vaccine in pregnancy, a cohort study examining child developmental outcomes is needed. There are a number of…
Women will be enrolled at or prior to prenatal visit at 34-40 weeks gestation with follow-up visits within 48 hours of delivery, and 6 and 12 months postpartum among the mother and infant. Maternal and infant measurements will be conducted at each visit. The purpose of the study is to estimate cardiovascular disease risk in healthy and medically complicated…
Researchers at Columbia are looking at the changes that happen in the placenta when people become pregnant. Participation in this study involves a blood draw at three time points. Participants will be paid $50 at each time point. Participants who complete all three time points will receive bonus compensation.
Researchers at Columbia are looking into possible viral causes of stillbirth or late-term miscarriages in patients. We are looking for people who have recently had a late-term pregnancy loss (within the past week). Participation in this research involves a one-time blood draw. Participants will receive $50.
Are you currently pregnant or were you pregnant in the last 2 years? We want to hear from you! We are conducting interviews to understand how we can support physical and mental health during pregnancy and postpartum. Interviews will take place virtually over Zoom or via telephone and last about 60 minutes. There are also options to participate in person (…
GO MOMs is an observational study designed to characterize the glycemic profile of pregnancy using continuous glucose monitoring (CGM) technology in order to develop criteria using CGM measurements and/or early pregnancy oral glucose tolerance testing (OGTT) at 10w0d-14w0d gestation that are predictive, along with clinical factors, of adverse pregnancy…
This is a prospective, single arm, three stage, multi-site, clinical investigation evaluating the safety and efficacy of the Carag Bioresorbable Septal Occluder (CBSO) to treat patients with clinically significant hole in the atrial septal defect compared to other commercially approved devices. The study is being done to determine the safety and efficacy of…
This prospective, multicenter, open-label, single arm, first-in human study will enroll up to 75 subjects aimed at examining the performance of the LAAC device for LAA closure.
The purpose of this research is to find out whether it is safe to shorten the length of time that people at high risk for bleeding take blood thinners after being treated with a coronary stent.
The purpose of this study is to test the effect of a drug called retosiban on stopping preterm labor and delaying the birth of her baby. We will also study the safety of the drug to find out what effects; good or bad, retosiban has on women in preterm labor and their fetuses. A previous small study, involving 93 women with preterm labor, found that…
This study is for patients with Coronary Artery Disease (CAD) and require a stent placement. The purpose of this clinical research study is to assess the safety and effectiveness of the Orsiro stent or a non-investigational Xience stent. The Orsiro stent is investigational, which means it is not yet approved by the FDA and can only be used in research…
If so, you may be able to take part in a clinical research study. This study is being done to see how wellcarbon dioxide (CO2) may provide relief from the pain associated with Trigeminal Neuralgia (TN). CO2 is a gas that is part of the air we breathe and is used to make bubbles in carbonated drinks. The screening and treatment office visit can be done in…
The purpose of this research study, is to learn whether an experimental device (called Evolut R) can help clear hardened blockage in coronary arteries (blood vessels that feed the heart muscle) in patients with a disease is called aortic stenosis.Subjects that choose to participate and are eligible will have their interventional cardiologist use this device…
This study plans to learn more about a device called the Cefaly and if it is effective for treating migraine attacks. This device is approved by the Food and Drug Administration(FDA) for the prevention of episodic migraines, but clinical data has not yet been collected on its effectiveness in treating migraine attacks.
The purpose of this study is to see if a new medication called ticagrelor given twice daily ismore effective than aspirin alone in preventing the occurrence of heart attack, stroke and/ordeath due to cardiovascular events in patients who have type 2 diabetes. Ticagrelor is anantiplatelet therapy (stop platelets from clumping together) and is approved for…
This study is for patients who have severe migraine headaches that might be a result of a hole in the heart wall called a Patent Foreman Ovale, or PFO. It is known that as many as 40% of patients with migraine headaches also have a PFO. It is not well understood how the two are related, or how having a hole in the heart wall could cause headaches. In this…
The purpose of this study is to survey patients who have undergone a percutaneous coronary intervention (PCI) at Columbia University Medical Center in which the physician used a stent called the Promus Premier stent. Patients will be asked to do a brief 15-30 minute survey regarding their health since the PCI and stent implantation.
This study plans to learn more about a device called the Cefaly and if it is effective for treating migraine attacks. This device is approved by the Food and Drug Administration (FDA) for the prevention of episodic migraines, but clinical data has not yet been collected on its effectiveness in treating migraine attacks. The Cefaly device works by generating…
This is a study of patients delivering at Columbia University Medical Center-Allen Hospital. The investigators will compare the change in maternal hemoglobin from postpartum day 1 to day 2 and also try to find out if there is a correlation between estimated blood loss and measured blood loss.
The purpose of this study is to evaluate the Biosensors BioFreedom Biolimus A9 Drug Coated Coronary Stent on people with coronary artery disease (blockages in the heart arteries) to determine if it is safe and effective.
The ENFORCE Teva Cluster Headache clinical trial is looking for people who have been diagnosed with episodic cluster headaches to participate. People who volunteer and qualify may have the opportunity to try an investigational study drug for cluster headaches. If you're 18 to 70 years old and have experienced cluster headaches for 12 months or more,…
The goal of the study is to determine whether coming to the hospital and having the labor started with medicine (i.e., labor induction) at 39 weeks of pregnancy can improve the baby's health at birth when compared with waiting for labor to start on its own.