Early Age-Related HearingLoss Investigation (EARHLI) is a study to obtain information on how a hearing aid-based intervention can prevent cognitive decline in those at risk for Alzheimer's Disease and…
The purpose of this study is to learn more about the mechanisms of hearingloss, specifically to learn how abnormalities in the brain may produce certain experiences that are common in patients with hearing…
We are currently looking for adult patients who have undergone successful treatment of their obstructive sleep apnea with a hypoglossal nerve stimulator implant (i.e. Inspire therapy). Participants should be willing to participate in at-home sleep studies and come to Columbia University Irving Medical Center for at least 2…
Cisplatin is a chemotherapy medicine that is used to treat a variety of cancers. At high total (cumulative) doses it can be associated with progressive and irreversible hearingloss. The purpose of this study is see if injections of OTO-104 can protect against hearing…
The purpose of this research is to find out whether it is safe to use a virus to deliver a new gene to the inner ear of people with hearingloss. This is a kind of gene therapy which involves gene transfer. Once the genetic material…
Our research team at Columbia University is trying to understand the impact of COVID-19 on smell and taste (chemosensory) dysfunction among adult patients from the Greater New York City area. Current areas of study include: 1) Investigation of smell and taste recovery patterns among patients with COVID-19; 2) Studies on how…
The Columbia University Department of Otolaryngology is interested in understanding altered flavor perception through the Cognitive Flavor Assessment Protocol (CFAP), a novel multisensory diagnostic and training framework that links smell and taste function to cognitive and emotional health. You can participate in this study if you are an adult between 18…
The purpose of these studies is to gain an understanding of the mechanisms that promote weight loss and improved glucose control. The ultimate goal is to identify therapeutic pathways for obesity and diabetes as a way to optimize surgical procedures and discover novel non-surgical targets for safe and effective drug therapy.…