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Displaying 1 - 20 of 20

Using a Robotic Walking Device for Stroke Survivors

Condition: Stroke
Investigator: Sunil Agrawal, PhD
Status: Currently Recruiting
A Tethered Pelvic Assist Device (TPAD) will provide wearers with gentle forces to evaluate the effects on walking.
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MyHand Project for Stroke Patients: Robotic Device Testing to Help People with Stroke use Their Weak Hand More Easily

Condition: Stroke
Investigator: Joel Stein, MD
Status: Currently Recruiting
My Hand Project for Stroke Patients: We are testing a robotic device to help people who had a stroke use their weak hand more easily. This research study would involve you wearing a hand robot that helps open and close your fingers in order to use your hand to pick up common everyday objects. During the study, you may be asked to try out different…
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Smelling the Juice: Functional Smell and Taste Preferences in Vaping and Cigarette Smoking

Condition: Addiction / Nicotine
Investigator: Jonathan Overdevest, MD, PhD
Status: Currently Recruiting
The Columbia Otolaryngology Department is interested in understanding the intersection of vaping, smell, and taste and their impact on individuals' preferences for certain flavors. Participation will involve answering a series of questionnaires in addition to completing a formal evaluation of your smell and taste with standardized measurements. You can…
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An observational study for patients diagnosed with mycosis fungoides cutaneous lymphoma and treated with Valchlor

Condition: Cancer / Lymphoma
Investigator: Larisa Geskin, MD
Status: Closed
The purpose of this study is to better understand the use of Valchlor in clinical practice. Other goals include describing the demographic and clinical characteristics of disease and health outcomes of patients treated with Valchlor. Participating in this study will not influence the usual care you receive from your doctor.
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A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Condition: Cancer / Lymphoma
Investigator: Nobuko Hijiya, MD
Status: Closed
This Phase III trial investigates if the incorporation of immunotherapy will improve progression-free survival (PFS) and maintain overall survival (OS) while simultaneously minimizing long-term morbidity and treatment-related mortality by reducing exposure to radiotherapy and high cumulative chemotherapy doses. The study will enroll patients ages 5 to 60…
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Educational Program for Adult Caregivers of Stroke Survivors

Condition: Stroke
Investigator: Lenin Grajo, PhD
Status: Closed
This program aims to help improve adult caregivers of stroke survivors ability to care for their stroke survivors with their daily needs. Each session will cover different topics which are important for caregivers to understand in order to best engage in their new role. Topics will include, but are not limited to: bathing, toileting, dressing, transfers,…
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Research Study for Arm Function after Stroke

Condition: Stroke
Investigator: Dawn Nilsen, EdD, OTR/L, FAOTA
Status: Closed
The purpose of this research is to learn about types of practice that may benefit stroke survivors when learning to use their weaker arm to perform a task. Potential participants will be asked to come to Columbia University Irving Medical Center (CUIMC) for a screening session. Eligible participants will be randomized into two groups with different practice…
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Study of Lenalidomide in Combination with Chemotherapy in Patients with HTLV-Associated Adult T-Cell Leukemia-Lymphoma (ATLL)

Condition: Cancer / Lymphoma
Investigator: Jennifer Amengual, MD
Status: Closed
This study is being done to determine if a study drug called lenalidomide can be combined with full doses of EPOCH chemotherapy for patients with Adult T-Cell Leukemia-Lymphoma (ATLL), and to define the highest dose and longest duration of lenalidomide that can be given safely in combination with EPOCH. EPOCH chemotherapy is a combination of five…
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VapeScan Heart and Lung Study

Condition: Addiction / Nicotine
Investigator: Ana Navas-Acien, MD, PHD, MPH
Status: Closed
The use of electronic cigarettes, also known as e-cigs or vaping, has increased among former smokers and young adults who have never smoked. Relatively little is known, however, about their health effects (whether they are adverse, have no effect, or are beneficial). The purpose of this research study is to evaluate (1) the association of e-cig use with…
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Cigarette Smokers Wanted for Research Study Examining the Effects of Nicotine on Attention, Memory, and Perception

Condition: Addiction / Nicotine
Investigator: Mariam Aly, PhD
Status: Closed
This is a four-session study in which we will be recruiting existing cigarette smokers to explore the competitive dynamics between memory encoding and memory retrieval. To participate, you will first go through a phone screening to determine eligibility and learn about the study. Then you will be asked to visit our facility at the Morningside Campus of…
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A new study for patients with Hodgkin's Lymphoma using study drug combination (brentuximab & bendamustine)

Condition: Cancer / Lymphoma
Investigator: Ahmed Sawas, MD
Status: Closed
The purpose of this study is to gather information about the effectiveness and safety of as drug called brentuximab vedotin when given in combination with another drug called bendamustine for Hodgkin Lymphoma. The study will assess the safety profile of the combination treatment and determine what proportion of patients achieve a complete remission.…
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Left atrial appendage closure device research study

Condition: Stroke
Investigator: Robert Sommer, MD
Status: Closed
The Amulet IDE trial is a prospective, randomized, multi-center active control worldwide trial, designed to evaluate the safety and effectiveness of the AMPLATZER Amulet Left Atrial Appendage Occluder. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device (treatment) or a Boston Scientific WATCHMAN LAA closure device (Control).…
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MyHand Project - Stroke

Condition: Stroke
Investigator: Joel Stein, MD
Status: Closed
We are looking for adults who have had a stroke to participate in testing of a new robotic device for the hand. If you had a stroke over six months ago and now have difficulty using your hand, you may qualify to participate in this study. Time commitment: ~4 weeks, 3x/week, Compensation: $50 per testing visit, $25 per training session.
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SMARTS 2

Condition: Stroke
Investigator: Joel Stein, MD
Status: Closed
Stroke often results in limitation of arm movements, from which many people do not fully recover. We believe that early and intensive therapy is important to enhance recovery of arm movements after stroke. We are doing this research study to see how much arm movements improve with intensive therapy in patients have had a stroke in the past 5 weeks. We will…
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Study of Ibrutinib in Pediatric and Young Adult Patients With Relapsed or Refractory Mature B-cell non-Hodgkin Lymphoma (Ages 1-30)

Condition: Cancer / Lymphoma
Investigator: Nobuko Hijiya, MD
Status: Closed
This is a 2-part, multicenter study of a study drug in pediatric and young adult patients with mature B-cell non-Hodgkin Lymphoma which has come back or has not responded to the standard therapy. The study treatment is considered an experimental because the study drug is not approved by the United States (US) Food and Drug Administration (FDA) for treating…
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Efficacy and Safety of Naloxone Lotion for Treatment of Itchiness in Patients with Mycosis Fungoides (MF) Form of Cutaneous T-cell Lymphoma

Condition: Cancer / Lymphoma
Investigator: Larisa Geskin, MD
Status: Closed
This is a phase 2 study to determine the efficacy and safety of Naloxone HCL Lotion 0.5% for the treatment of mycosis fungoides (MF) type of cutaneous T-cell lymphoma (CTCL). Selected subjects will have the study drug applied to determine its effect on reducing itchiness and any potential side effects. Naloxone has previously been approved for direct blood…
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A study for patients with Diffuse Large B-cell Lymphoma using study drug IMO-8400

Condition: Cancer / Lymphoma
Investigator: Ahmed Sawas, MD
Status: Closed
The purpose of this study is to see if study drug IMO-8400 is safe and effective in the treatment of patientswith relapsed or refractory Diffuse Large B-Cell Lymphoma following conventional treatment.Examples of conventional treatment are radiotherapy, immunotherapy, chemotherapy, orradioimmunotherapy. Patients are scheduled to participate in this study…
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Phase 3 Trial to Determine the Efficacy of Topical Hypericin combined with Fluorescent Light Therapy on Cutaneous T-Cell Lymphoma

Condition: Cancer / Lymphoma
Investigator: Larisa Geskin, MD
Status: Closed
This is a phase 3 clinical trial to determine the efficacy of topical SGX301 (synthetic hypericin) in combination with visible light therapy on cutaneous T-cell lymphoma (CTCL). Selected subjects can participate in 3 cycles each consisting of a 6 week treatment period where a chosen lesion will be treated with the study ointment (twice a week) followed by…
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A study for subjects with refractory or relapsed lymphoid malignancies using study drug, AGS67E

Condition: Cancer / Lymphoma
Investigator: Ahmed Sawas, MD
Status: Closed
The purpose of this study is to determine a safe dose by testingthe investigational product, AGS67E at different dose levels. Secondly, to test what effects, good and/or bad, it has on subjects with refractory or relapsed non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), prolymphocytic leukemia (PLL) or hairy cell leukemia (HCL). We will also…
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A study for patients with Cutaneous T-Cell Lymphoma/Mycosis Fungoides using topical lotion Naloxone in the treatment of itching

Condition: Cancer / Lymphoma
Investigator: Larisa Geskin, MD
Status: Closed
You are being asked to participate in a research study because you have Cutaneous T-Cell Lymphoma/Mycosis Fungoides, and one of your symptoms is itching. This study is being done to assess the efficacy and safety of Naloxone HCL Lotion 0.5% compared to Vehicle Lotion for the treatment of itching in patients with mycosis fungoides (MF) which is a type of…
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