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The Cancer of the Pancreas Screening-5 Study (CAPS5 Study)

Condition: Cancer / Pancreatic Cancer

Status: Currently Recruiting

Pancreatic cancer is a deadly disease and the best hope for improving the chances of survival is to find it early. Some patients, called "high risk", have an inherited predisposition to pancreatic cancer. Certain medical centers have started programs where "high risk patients" undergo testing, such as receiving imaging scans, to look for…

Collection of Blood and Skin Samples from Patients with Hair and Skin Disorders

Condition: Hair and Skin Disorders

Investigator: Angela Christiano, PhD

Status: Currently Recruiting

The purpose of this study is to examine the causes and pathology of alopecia areata and other hair and skin disorders. Skin biopsies and blood and/or clinical information collected in the study will be used for research aiming at developing new options for the treatment of alopecia areata and other skin and hair disorders.

Genetic Studies of Hidradenitis Suppurativa

Condition: Hair and Skin Disorders

Investigator: Lynn Petukhova, PhD

Status: Closed

Genetic studies help us to understand why some people develop certain diseases while others don't and also provide important clues about how best to treat the disease.

Insulin Action in Psoriasis

Condition: Hair and Skin Disorders

Investigator: Joshua Cook, MD, PhD

Status: Closed

We are conducting a research study on how psoriasis might be caused or worsened by high levels of the blood sugar-lowering hormone insulin. We are seeking people with plaque psoriasis, ages 18-65, who are overweight or obese with a body mass index of 25-35. Participants will have blood drawn and small skin biopsies taken from psoriasis plaques and nearby…

Study of Multiple Treatment Combinations in Patients with Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)

Condition: Cancer / Pancreatic Cancer

Investigator: Gulam Manji, MD, PhD

Status: Closed

The purpose of this study is to learn which treatment works best in patients with pancreatic cancer. The study explores multiple treatment combinations. A study drug called atezolizumab may be combined with other drugs such as cobimetinib, PEGPH20, and BL-8040. Patients may also be assigned to receive standard chemotherapy treatment.

A study for patients with episodic or chronic migraine using the Cefaly device for the acute treatment of migraine headaches

Condition: Headaches / Migraines

Investigator: Denise Chou, MD

Status: Closed

This study plans to learn more about a device called the Cefaly and if it is effective for treating migraine attacks. This device is approved by the Food and Drug Administration(FDA) for the prevention of episodic migraines, but clinical data has not yet been collected on its effectiveness in treating migraine attacks.

A study to reduce episodic and/or chronic migraine headache symptoms in patients who have a common heart defect called Patent Foramen Ovale

Condition: Headaches / Migraines

Investigator: Robert Sommer, MD

Status: Closed

This study is for patients who have severe migraine headaches that might be a result of a hole in the heart wall called a Patent Foreman Ovale, or PFO. It is known that as many as 40% of patients with migraine headaches also have a PFO. It is not well understood how the two are related, or how having a hole in the heart wall could cause headaches. In this…

Acute treatment of Migraine using the Cefaly device

Condition: Headaches / Migraines

Investigator: Denise Chou, MD

Status: Closed

This study plans to learn more about a device called the Cefaly and if it is effective for treating migraine attacks. This device is approved by the Food and Drug Administration (FDA) for the prevention of episodic migraines, but clinical data has not yet been collected on its effectiveness in treating migraine attacks. The Cefaly device works by generating…

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