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Displaying 1 - 12 of 12

DEFENDER. Was it Fentanyl?

Condition: Addiction / Opioids
Investigator: Dana Sacco, MD
Status: Currently Recruiting
The purpose of this research study is to evaluate how commonly drug overdoses in our community involve fentanyl and xylazine. We know that often drugs such as heroin, oxycontin, and even cocaine and methamphetamine, actually contain these additives, even though the person buying the drugs is not aware.
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A Study of LYN-014 in Individuals with Opioid Use Disorder who are Stable on Methadone Therapy

Condition: Addiction / Opioids
Investigator: Sandra Comer, PhD
Status: Closed
Have an Opioid Use Disorder? We need your help for an inpatient clinical research study! Help the New York State Psychiatric Institute research better treatment options for those with opioid use disorder.You could earn up to $12,017.00.You must meet the following criteria: - Age 18 -59 years old- Have opioid use disorder- Be currently taking an oral daily…
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Brain imaging in bipolar depression to understand the role of inflammation in its treatment.

Condition: Psychiatric Disorders / Bipolar Disorder
Investigator: Martin Lan, MD
Status: Closed
This is a research study to understand what causes bipolar disorder and how medications treat bipolar depression. Particularly, we are looking at the importance of inflammation in the process. If you participate, you will receive an experimental medication for your depression named ethyl eicosapentaenoic acid (ethyl EPA), an omega 3 fatty acid. You will…
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The Relationship Between Heroin Use and Cellular Aging

Condition: Addiction / Opioids
Investigator: Jermaine Jones, PhD
Status: Closed
Healthy Black and Latino heroin users (male and female ages 25-55) are needed for a research study assessing the relationship between heroin use and cellular aging. The study involves a single visit to the New York State Psychiatric Institute, and consists of questionnaires and the collection of a blood sample for genetic testing. The visit will take about…
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Research Study offering Treatment for Self-Injury (Bipolar Disorder)

Condition: Psychiatric Disorders / Bipolar Disorder
Investigator: Jeffrey Miller, MD
Status: Closed
The goal of this study is to examine how effective and well-tolerated a possible new treatment for individuals who injure themselves frequently will be. All research procedures can be done from home no in-person visits are required. We are studying a minimal-risk form of electrical brain stimulation called transcranial direct current stimulation, or tDCS.…
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Functional Brain Mechanisms Underlying the Anti-Suicidal Effects of Buprenorphine in Opioid Use Disorder

Condition: Addiction / Opioids
Investigator: Mina Rizk, MD
Status: Closed
This research study uses MRI scans to compare the effect of two medications on suicidal thoughts and brain activity in people who have opioid use disorder. We hope to develop a better understanding of how well these two medications help depression and suicidal thoughts. You may qualify if you have opioid use disorder and suicidal thoughts. Participation…
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Healthy heroin users needed

Condition: Addiction / Opioids
Investigator: Sandra Comer, PhD
Status: Closed
Healthy heroin users (men and women, ages 21-59) are needed for an eight-week inpatient study investigating medication effects at the NY State Psychiatric Institute. Earn approximately $6,550 - $7,350.
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Brain imaging in bipolar depression to be able to predict who will respond to antidepressant treatment

Condition: Psychiatric Disorders / Bipolar Disorder
Investigator: Martin Lan, MD
Status: Closed
We are trying to understand what causes bipolar disorder and how medications treat bipolar depression. If you participate, you will have two different brain scans (MRI and PET scan). You will also have antidepressant treatment for free. We will then be able to see whether information on the brain scans connects with how people do on the medications. The…
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Medication trial for the treatment of opiate use disorder

Condition: Addiction / Opioids
Investigator: Frances Levin, MD
Status: Closed
This study proposes to recruit patients with Opioid Use Disorder (OUD) seeking treatment into our program of a 5 day outpatient detoxification and naltrexone induction followed by a relapse-prevention treatment with Extended release-naltrexone (XR-NTX) for 8 weeks.
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Brain imaging in bipolar depression to understand the antidepressant mechanism of lurasidone (Latuda).

Condition: Psychiatric Disorders / Bipolar Disorder
Investigator: Martin Lan, MD
Status: Closed
We are trying to understand what causes bipolar disorder and how medications treat bipolar depression. Particularly, we are looking at the importance of dopamine signaling in the process. If you participate, you will have two different brain scans (MRI and PET scan). You will also have treatment for your depression with an FDA approved medication,…
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Lumateperone for the Treatment of Bipolar Disorder

Condition: Psychiatric Disorders / Bipolar Disorder
Investigator: David Hellerstein, MD
Status: Closed
This study is a double-blind and placebo-controlled study to assess its efficacy of the new drug Lumateperone for patients with Major Depressive Episodes associated with Bipolar I and Bipolar II disorder. Lumateperone is thought to exert its antidepressant effect through interaction with sereotogenic, dopaminergic, and glutamergic neurotransmitter targets.…
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MRI Effects of D-cycloserine & Lurasidone in Bipolar Depression

Condition: Psychiatric Disorders / Bipolar Disorder
Investigator: Joshua Kantrowitz, Md
Status: Closed
We will evaluate the D-cycloserine (DCS) and lurasidone with MRI measurement of brain responses to DCS. DCS is a drug that works on the same brain receptor as ketamine. DCS is not approved by the FDA for bipolar depression. Study participants will receive a dose of lurasidone or placebo in one MRI and a dose of DCS in another, followed by an optional follow…
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