The goal of this research is to combine non-invasive brain and sensory nerve stimulation to investigate their influence on hand function. Many adults with hemiplegic CP no longer actively receive therapies but have further hand goals they want to achieve. The information we learn from this study may help us learn how to design future interventions to help…
We are inviting patients with active Rheumatoid Arthritis (RA) to help us better understand how treatment options affect inflammation in soft tissues. With a combination of blood work, a full-body FDG PET-CT scan, questionnaires, and a soft tissue biopsy (from an area around the belly button), we hope to see how RA interacts with these multiple areas of…
The purpose of this study is to: 1. Determine if a tele-rehabilitation home exercise program is helpful in promoting adherence to an exercise program in adults with CP and 2. to determine if a tele-health exercise program improves fitness and functional mobility in adults with CP. This study involves participation in a 10-week remote (Zoom) program to…
Ambulatory youth with cerebral palsy (CP) aged 8-16 years old are invited to participate in a virtual reality (VR) game play session to learn about youth motivation and satisfaction with VR to promote fitness and mobility. The session will be approximately 2 hours and will be conducted in the Programs in Physical Therapy (PT) PACE Lab @ 617 W. 168th St.,…
We are looking for adults with cerebral palsy who are 18 and over for ultrasound study of nerves at the wrist. We are assessing the symptoms of Carpal Tunnel Syndrome in adults with cerebral palsy. The study will involve a survey to describe their medical history, procedures (especially of the arms), use of adaptive equipment (such as walkers, wheelchairs…
This study is for infants that have been genetically diagnosed with Spinal Muscular Atrophy (SMA) and are currently not showing any signs or symptoms of the disease. The purpose of this study is to see whether ISIS 396443 has any effects (good or bad) on infants with SMA (who do not yet show signs or symptoms of the disease) and to see if ISIS 396443 can…
Abnormal muscle tightness -known as spasticity- in the leg can happen when a child has cerebral palsy. If your child has spasticity, they may find it difficult to straighten their leg and experience stiffness. The goal of this study is to collect information from participants about the safety and effectiveness of using BOTOX to treat arm and hand spasticity…
The purpose of this study is to evaluate the safety, tolerability and effectiveness of a study drug called ISIS-396443 when using it to treat children with later-onset spinal muscular atrophy (SMA). SMA is a neuromuscular disease that causes a degeneration (a breakdown) of the motor neurons in the spinal cord, resulting in a weakening of the muscles in…
Abnormal muscle tightness -known as spasticity- in the arm and hand can happen when a child has cerebral palsy. If your child has spasticity, they may find it difficult to straighten their hand and/or arm and experience stiffness. The goal of this study is to collect information from participants about the safety and effectiveness of using BOTOX to treat…
The study aims to compare the effect two different RA treatments on cardiovascular health in patients who are considering a treatment change. The study is recruiting patients who are only taking methotrexate and are switching treatment due to a lack of improvement. The trial will randomize participants to take a TNF inhibitor (Enbrel or Humira) in addition…
We are doing a research study to learn more about why people with rheumatoid arthritis (RA) are prone to heart disease. We are recruiting patients diagnosed with Rheumatoid Arthritis without a personal history of heart disease. This study involves one initial full visit as described below, and a brief follow up visit that will take place approximately 2 or…