225 Studies Now Enrolling
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Displaying 201 - 218 of 218
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
We are working on a new HIV vaccine study that builds on past success and other ongoing studies. This new study is called HVTN 120 and is testing a vaccine for HIV prevention. The Thai Trial has been the only study where the vaccines were partially protective in preventing HIV. We learned a lot from that study, and are now improving on next generation of…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Closed
The overall goal of this project is to determine whether short sleep duration is a risk factor for cardiovascular disease in women. We are currently looking for healthy, non-smoking women to participate in a sleep study. You must be willing to come to Columbia University Medical Center once a week for two 6-week periods and regularly sleep at least 7-9…
Condition: Healthy Volunteers
Investigator: Moise Desvarieux, MD, PhD
Status: Closed
We are looking for people ages 65 and older to help us evaluate if an investigational drug improves muscle function, which can reduce risk of falls and fractures. To be considered for the study, you: 1. Must complete a pre-screening phone interview to assess your eligibility 2. If you are eligible, you will be invited to attend an in-person appointment at…
Condition: Lung Disease
Investigator: David Lederer, MD
Status: Closed
The purpose of this study is to find out if subjects can take the prescribed dose of GBT440 without problems, and whether GBT440 is safe and helps subjects with IPF. GBT440 is called an investigational or experimental drug because it has not been approved for use in people by the Food and Drug Administration (FDA), the branch of U.S. government which…
Condition: Healthy Volunteers
Investigator: Karen Marder, MD, MPH
Status: Closed
This study is recruiting people who have a family history of a neurodegenerative diseases, such as Alzheimer's disease or other form of dementia including frontotemporal dementia and prion disease, who are interested in doing predictive genetic testing. Participants will complete questionnaires prior to testing and then 1 month and 6 months after…
Condition: Healthy Volunteers / Exercise
Investigator: Richard Sloan, PhD
Status: Closed
This study focuses on the effects of aerobic conditioning on cardiovascular function and inflammatory response. Eligible participants will complete an exercise stress test, laboratory visit, and cognitive testing session at three specific time points over the course of the study. Once the initial set of appointments is complete, participants are randomly…
Condition: Healthy Volunteers
Investigator: Jeffrey Miller, MD
Status: Closed
The purpose of this study is to use Positron Emission Tomography (PET) to identify changes in brain chemistry that may cause an episode of depression. This study will be carried out in approximately 30 subjects. PET is a technique that provides "pictures" of chemical connections in the brain by injecting and monitoring a radioactive substance. In…
Condition: Healthy Volunteers
Investigator: Richard Sloan, PhD
Status: Closed
The purpose of this research study is to determine whether ambulatory monitoring of blood pressure measured by a finger touch blood pressure monitor is a viable approach to measuring blood pressure in the field. A secondary aim is to determine whether the finger touch blood pressure monitor is influenced by individual differences in current stress levels…
Condition: Healthy Volunteers
Investigator: Paula Castano, MD, MPH
Status: Closed
Columbia University is conducting a contraceptive clinical trial looking at two intrauterine devices, one of which is investigational. Pre-menopausal women ages 16-40 who are generally healthy, sexually active, at risk for pregnancy, and are not at risk for sexually transmitted infections may qualify.
Condition: Healthy Volunteers
Investigator: William Whang
Status: Closed
The purpose of this study is to evaluate the performance of a remote patient monitoring device against more established wired monitoring devices during common activities and low to moderate exercise.The goal of this study is to determine how the Zephyr BioPatch will work compared to more established wired monitoring devices. This study involves one visit,…
Condition: Lung Disease / Cystic Fibrosis
Investigator: Emily DiMango, MD
Status: Closed
The purpose of this study is to assess how effective the study drug Pulmaquin is in the management of chronic lung infections with Pseudomonas aeruginosa in subjects with non cystic fibrosis (nonCF) bronchiectasis by evaluating the time to first pulmonary exacerbation. A pulmonary exacerbation is defined as the new appearance or worsening in 4 or more of…
Condition: Healthy Volunteers
Investigator: Julia Wynn
Status: Closed
This study is evaluating genomic screening in Ashkenazi Jewish and Hispanic communities. Genomic screening is done by collecting a blood sample and looking at a person's genes to learn if they are at high risk for certain health problems like cancer or heart disease or are at risk to have a child with a genetic condition. The study is designed to…
Condition: Healthy Volunteers
Investigator: Eldad Hod, MD
Status: Closed
One of the consequences of donating blood is iron deficiency. In this study, we will screen healthy frequent blood donors for iron deficiency. We will enroll iron deficient donors and randomize them to intravenous iron treatment or placebo in order to determine whether iron deficiency has any harmful effects on the blood supply and the donors themselves.
Condition: Healthy Volunteers
Investigator: Brooke Aggarwal, EdD, MS, FAHA
Status: Closed
This study is active but is no longer enrolling new subjects.
Condition: Healthy Volunteers
Investigator: Loren Gianini, PhD
Status: Closed
The goal of this study is to better understand why some people have managed to lose weight and keep it off while others have not. We are recruiting people who have lost weight and kept it off as well as healthy non-dieters with overweight or obesity who are not trying to lose weight. Study participation involves computer tasks, brain imaging, and eating a…
Condition: Lung Disease
Investigator: Nina Patel, MD
Status: Closed
The purpose of this study is to investigate the safety of adding nentedanib to treatment with pifenidone in patients with Idiopathic Pulmonary Fibrosis (IPF). Eligible patients must be receiving consistent treatment with pifenidone for at least 16 weeks on a stable dose. Nintedanib will be added as an additional treatment for IPF (combination treatment) for…
Condition: Healthy Volunteers
Investigator: Blandine Laferrere, MD, PhD
Status: Closed
This pilot study is designed to examine the effect of a novel type of lifestyle intervention, administered via a smartphone app, on weight loss and improvement of metabolic health in individuals with overweight and/or obesity. A mobile application will be used to document eating behavior through photos. In addition, participants will receive personalized…
Condition: Healthy Volunteers
Investigator: Daphna Shohamy, PhD
Status: Closed
The Learning Lab at Columbia University is conducting computer based behavioral studies to address fundamental questions regarding the nature of learning, memory, and decision making. Specifically, we will use behavioral methods to investigate the extent to which learning, memory and decision making may be modulated by factors such as novelty, trial-by-…