232 Studies Now Enrolling
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Displaying 1 - 11 of 11
Condition: Transplant / Kidney Transplant
Investigator: Lloyd Ratner, MD, MPH, FACS
Status: Currently Recruiting
This study is testing whether giving an investigational drug called C1 esterase inhibitor (C1INH) directly into the donor kidney before transplant can improve kidney function one year after surgery. At the time of the deceased donor kidney transplant, participants will be randomly assigned to received a kidney that has been treated with either C1INH or a…
Condition: Transplant / Kidney Transplant
Investigator: Joshua Weiner, MD
Status: Currently Recruiting
The goal of this clinical trial is to learn if an investigational medication called siplizumab can prevent rejection of a kidney transplant patients with end stage kidney disease. The study will compare two different doses of siplizumab to a medication that is standardly used post kidney transplant to prevent rejection, rabbit anti-thymocyte globulin (rATG…
Condition: Psychiatric Disorders / Obsessive Compulsive Disorder (OCD)
Investigator: Dana Diaz
Status: Currently Recruiting
This research study will examine how an iPad-based cognitive training game combined with cognitive behavioral therapy (CBT) helps children with excessive worries and related repetitive behaviors (obsessive compulsive behaviors). This study will take place at Columbia University in Manhattan. Participation includes a clinical evaluation and questionnaires,…
Condition: Psychiatric Disorders / Depression
Investigator: J. John Mann, MD
Status: Currently Recruiting
We are conducting a study on depression and suicide risk, and participants can earn up to $300 for taking part. Suicide rates in the U.S. are rising, and new treatments are urgently needed. This study focuses on the brain chemical glutamate, which may play an important role in mood and mental health. We will compare glutamate levels at rest and during…
Condition: Psychiatric Disorders
Investigator: Peter Dayan, MD
Status: Currently Recruiting
The study uses brain imaging and cortisol to understand risk and protective factors for mental health among adolescents on social media. We are currently recruiting adolescents ages 14-18 who struggle with mental health. To participate in our study, we would ask your child to: (a) complete a mental health interview (over Zoom), (b) complete a Magnetic…
Condition: Transplant / Kidney Transplant
Investigator: Lloyd Ratner, MD, MPH, FACS
Status: Currently Recruiting
This study is testing whether a new investigational medicine called frexalimab can safely and effectively prevent kidney transplant rejection compared to tacrolimus, a standard medication currently used after transplant. Participants will be randomly assigned to receive either frexalimab (given by injection every 4 weeks) or tacrolimus (taken as capsules…
Condition: Transplant / Kidney Transplant
Investigator: Lloyd Ratner, MD, MPH, FACS
Status: Currently Recruiting
The main goal of this clinical trial is to determine if an investigational medication called VEL101 is safe, well tolerated, and effective in people receiving a new kidney transplant. Participants will be randomly assigned to 2 different doses of VEL-101 or to tacrolimus, which is standardly used post-transplant to prevent rejection. Participants will be…
Condition: Psychiatric Disorders / Eating Disorders
Investigator: Timothy Walsh, MD
Status: Currently Recruiting
Anorexia Nervosa is a serious illness and relapse rates are high. We have shown that behavioral routines get stuck/entrenched. Our newest research, Relapse Prevention and Changing Habits (REACH+) for Anorexia Nervosa, aims to help patients minimize unhelpful routines and develop more healthful recovery-oriented behavior. Participants will complete initial…
Condition: Psychiatric Disorders / Schizophrenia
Investigator: Guillermo Horga, MD, PhD
Status: Currently Recruiting
In this study, we are trying to learn more about the symptoms of psychosis, specifically to learn how alterations in the brain may produce certain experiences (including voice hearing or auditory hallucinations) that are common in people with psychosis or schizophrenia. The study involves clinical interviews, computer tests, and magnetic resonance imaging (…
Condition: Psychiatric Disorders / Depression
Investigator: Randy Auerbach, PhD
Status: Currently Recruiting
We are recruiting depressed adolescents ages 13-18 years. As a participant in our study, we will: (1) interview your child about current and past thoughts, feelings, and behaviors, (2) teach your child mindfulness strategies, (3) collect brain activity data with MRI (non-invasive) while your child practices mindfulness, and (4) send short surveys to your…
Condition: Psychiatric Disorders / Depression
Investigator: Marcella Walker, MD
Status: Currently Recruiting
Depression and some antidepressants may be associated with an increased risk of breaking a bone. It is not clear why this could be the case. It is possible that depression and/or certain medications used for the treatment of depression cause bone loss, increase the risk of falls, are associated with lower physical activity, or effects on muscle function.…