224 Studies Now Enrolling
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Displaying 1 - 22 of 22
Condition: Addiction / Opioids
Investigator: Felipe Castillo, Md
Status: Currently Recruiting
Looking for participants aged 18 to 55 who have trouble with heroin or other opiates to participate in a month-long research study at Columbia University Irving Medical Center evaluating the relationship between brain tasks and memory.
Condition: Addiction / Opioids
Investigator: Dana Sacco, MD
Status: Currently Recruiting
The purpose of this research study is to evaluate how commonly drug overdoses in our community involve fentanyl and xylazine. We know that often drugs such as heroin, oxycontin, and even cocaine and methamphetamine, actually contain these additives, even though the person buying the drugs is not aware.
Condition: Addiction / Opioids
Investigator: Rachel Luba, PhD
Status: Currently Recruiting
Columbia University Medical Center is recruiting individuals ages 18-65 who are seeking treatment for opioid use disorder to participate in a research treatment study. For your participation, you'll receive treatment with buprenorphine (either sublingual or injectable) at no cost. Participants will complete an overnight inpatient stay to start…
Condition: Addiction / Nicotine
Investigator: Jonathan Overdevest, MD, PhD
Status: Currently Recruiting
The Columbia Otolaryngology Department is interested in understanding the intersection of vaping, smell, and taste and their impact on individuals' preferences for certain flavors. Participation will involve answering a series of questionnaires in addition to completing a formal evaluation of your smell and taste with standardized measurements. You can…
Condition: Endocrine & Metabolic Disease / Cushing's Disease
Investigator: Pamela Freda, MD
Status: Closed
This study is for individuals who have Cushings disease and want to join voluntarily in this study to find out if a study drug called osilodrostat (LCI699) is safe and has beneficial effects in people who have Cushings disease. Cushings disease is a rare but debilitating disease. Cushings disease is caused by a benign tumor of the pituitary gland. The tumor…
Condition: Endocrine & Metabolic Disease / Cushing's Disease
Investigator: Amanda Tsang
Status: Closed
The purpose of this study is to determine if measuring blood levels of proteins called POMC, AgRP, and chromogrannin A (CGA) can be used to diagnose and track tumor growth and recurrence in patients that have ACTH-dependent Cushing's syndrome, non-secreting pituitary tumors, and other neuroendocrine tumors. We invite you to participate if you have: a…
Condition: Neurological Disorders / Huntington's Disease
Investigator: Ashwini Rao, EdD, OTR
Status: Closed
Dance is a complex activity involving the integration of rhythm, spatial patterns, synchronization to external stimuli and whole-body coordination. While regular exercise is often recommended for people with Huntington's Disease (HD), there are no studies examining the use of dance to improve balance and mobility and positively affect the quality of…
Condition: Addiction / Alcohol
Investigator: A. Benjamin Srivastava, MD
Status: Closed
Columbia University Medical Center is recruiting individuals ages 21-55 who are seeking treatment for alcohol problems to participate in a research study involving treatment. For your participation, you'll receive treatment with disulfiram (brand name Antabuse) at no cost. You be treated with disulfiram for approximately 13 weeks and undergo brain…
Condition: Neurological Disorders / Huntington's Disease
Investigator: Karen Marder, MD, MPH
Status: Closed
The DIMENSION Study is evaluating the safety and effect on cognitive symptoms of an investigational oral drug in adults with early Huntington's disease. Cognitive symptoms may include difficulty paying attention or trouble thinking through steps of an activity or complex problems. Symptoms may also include difficulty planning, remembering, and staying…
Condition: Addiction / Nicotine
Investigator: Ana Navas-Acien, MD, PHD, MPH
Status: Closed
The use of electronic cigarettes, also known as e-cigs or vaping, has increased among former smokers and young adults who have never smoked. Relatively little is known, however, about their health effects (whether they are adverse, have no effect, or are beneficial). The purpose of this research study is to evaluate (1) the association of e-cig use with…
Condition: Addiction / Marijuana
Investigator: Suzette Evans, PhD
Status: Closed
RESEARCH VOLUNTEERS: Healthy male and female (age 21-60) MARIJUANA SMOKERS needed to study effects of marijuana on brain activity and decision-making. The study involves 2-3 outpatient visits and a 5-day/5-night stay at the NYS Psychiatric Institute and includes Magnetic Resonance Imaging (MRI) scans. Compensation for time could be between $870-$1230 (…
Condition: Addiction / Nicotine
Investigator: Mariam Aly, PhD
Status: Closed
This is a four-session study in which we will be recruiting existing cigarette smokers to explore the competitive dynamics between memory encoding and memory retrieval. To participate, you will first go through a phone screening to determine eligibility and learn about the study. Then you will be asked to visit our facility at the Morningside Campus of…
Condition: Addiction / Opioids
Investigator: Sandra Comer, PhD
Status: Closed
Have an Opioid Use Disorder? We need your help for an inpatient clinical research study! Help the New York State Psychiatric Institute research better treatment options for those with opioid use disorder.You could earn up to $12,017.00.You must meet the following criteria: - Age 18 -59 years old- Have opioid use disorder- Be currently taking an oral daily…
Condition: Addiction / Cocaine
Investigator: Frances Levin, MD
Status: Closed
This study will test a computer-based behavioral intervention to decrease cocaine use. Those who fail to achieve cocaine abstinence after the first 4 weeks while receiving the behavioral treatment will continue the behavioral treatment and be randomly assigned to one of two groups (one group will receive Adderall-XR (MAS-ER) and the other group will receive…
Condition: Addiction
Investigator: Sandra Comer, PhD
Status: Closed
This 8-week inpatient study seeks to recruit healthy male and female patients who are currently using heroin or non-medically using opioid analgesics. Following screening, participants are admitted onto the inpatient unit where they complete testing sessions throughout the inpatient stay. Participants are compensated for each screening visit and for each…
Condition: Endocrine & Metabolic Disease / Cushing's Disease
Investigator: Pamela Freda, MD
Status: Closed
The purpose of this study is to confirm the effectiveness and safety of LCI699 in treating patients with Cushing's disease. Patients will be treated with the invesitigational drug LCI699 at doses up to 60 mg a day, and possibly for a short period of time with placebo. A placebo is a dummy drug ("pill") with no active medicine inside.
Condition: Addiction / Opioids
Investigator: Mina Rizk, MD
Status: Closed
This research study uses MRI scans to compare the effect of two medications on suicidal thoughts and brain activity in people who have opioid use disorder. We hope to develop a better understanding of how well these two medications help depression and suicidal thoughts. You may qualify if you have opioid use disorder and suicidal thoughts. Participation…
Condition: Addiction / Marijuana
Investigator: Frances Levin, MD
Status: Closed
The study is an outpatient treatment study of the safety and benefit of extended-release mixed amphetamine salt (Adderall-XR) in the treatment of individuals with cannabis use disorder and Attention Deficit/Hyperactivity Disorder (ADHD). The study is a 13-week trial and requires participants to come twice per week. The primary objective of the study is to…
Condition: Addiction / Opioids
Investigator: Sandra Comer, PhD
Status: Closed
Healthy heroin users (men and women, ages 21-59) are needed for an eight-week inpatient study investigating medication effects at the NY State Psychiatric Institute. Earn approximately $6,550 - $7,350.
Condition: Addiction / Cocaine
Investigator: Frances Levin, MD
Status: Closed
The study is a two group outpatient study, one group receiving medications (Adderall-XR and topiramate) and one group receiving a placebo (inactive sugar pill). The study is looking at the safety and effectiveness of Adderall-XR (MAS-ER) and topiramate in the treatment of cocaine dependence. It is a 14-week trial that requires patients to attend visits 3…
Condition: Addiction / Opioids
Investigator: Frances Levin, MD
Status: Closed
This study proposes to recruit patients with Opioid Use Disorder (OUD) seeking treatment into our program of a 5 day outpatient detoxification and naltrexone induction followed by a relapse-prevention treatment with Extended release-naltrexone (XR-NTX) for 8 weeks.
Condition: Neurological Disorders / Huntington's Disease
Investigator: Karen Marder, MD, MPH
Status: Closed
The purpose of this research study is to find out whether a new investigational drug called SRX246, which might be useful to Huntington's Disease (HD) patients who sometimes feel irritable, angry, or even aggressive, is well tolerated and safe when it is given two times a day by mouth at doses as high as 160 mg. As part of this study, we will use a…