The goal of this research is to combine non-invasive brain and sensory nerve stimulation to investigate their influence on hand function. Many adults with hemiplegic CP no longer actively receive therapies but have further hand goals they want to achieve. The information we learn from this study may help us learn how to design future interventions to help…
This study aims to collect information about the symptoms and treatments of patients who have severely clogged arteries and are treated with commercially available Boston Scientific Corporation drug-eluting devices marketed for the treatment of lesions located in the peripheral vasculature. Participation in the study is expected to last for up to two (2)…
This study is for individuals who have Cushings disease and want to join voluntarily in this study to find out if a study drug called osilodrostat (LCI699) is safe and has beneficial effects in people who have Cushings disease. Cushings disease is a rare but debilitating disease. Cushings disease is caused by a benign tumor of the pituitary gland. The tumor…
The purpose of this study is to determine if measuring blood levels of proteins called POMC, AgRP, and chromogrannin A (CGA) can be used to diagnose and track tumor growth and recurrence in patients that have ACTH-dependent Cushing's syndrome, non-secreting pituitary tumors, and other neuroendocrine tumors. We invite you to participate if you have: a…
The purpose of this study is to: 1. Determine if a tele-rehabilitation home exercise program is helpful in promoting adherence to an exercise program in adults with CP and 2. to determine if a tele-health exercise program improves fitness and functional mobility in adults with CP. This study involves participation in a 10-week remote (Zoom) program to…
This is a prospective, multi-center, observational, post-market study that will evaluate the safety and procedural success of performing trans-radial access for treatment of atherosclerotic lesions in the lower extremities. This research study will collect outcome data of patients undergoing percutaneous endovascular treatment of Peripheral Artery Disease (…
Ambulatory youth with cerebral palsy (CP) aged 8-16 years old are invited to participate in a virtual reality (VR) game play session to learn about youth motivation and satisfaction with VR to promote fitness and mobility. The session will be approximately 2 hours and will be conducted in the Programs in Physical Therapy (PT) PACE Lab @ 617 W. 168th St.,…
We are looking for adults with cerebral palsy who are 18 and over for ultrasound study of nerves at the wrist. We are assessing the symptoms of Carpal Tunnel Syndrome in adults with cerebral palsy. The study will involve a survey to describe their medical history, procedures (especially of the arms), use of adaptive equipment (such as walkers, wheelchairs…
The purpose of this study is to confirm the effectiveness and safety of LCI699 in treating patients with Cushing's disease. Patients will be treated with the invesitigational drug LCI699 at doses up to 60 mg a day, and possibly for a short period of time with placebo. A placebo is a dummy drug ("pill") with no active medicine inside.
This study is to test if a combination drug/device therapy using TEMSIROLIMUS (Temsirolimus Injection), with or without the generic steroid DEXAMETHASONE (Dexamethasone Sodium Phosphate Injection), can be delivered safely into the tissue around the blood vessel wall at the time of an angioplasty ( which is a a procedure to open blocked arteries and restore…
The purpose of this study is to deterimine if the Drug-Coated Chocolate Touch Balloon Catheters is safe and effective compared to a drug-coated balloon that is already approved in patients with a blockage in the blood vessels of their leg.
This study is for patients who suffer from a condition where one of the blood vessels that deliver blood to your leg has a significant narrowing. This is called peripheral artery disease (PAD). The narrowing may be suitable for a treatment technique called balloon angioplasty. One of the therapies that has been used to treat PAD is balloon angioplasty. It…
Abnormal muscle tightness -known as spasticity- in the leg can happen when a child has cerebral palsy. If your child has spasticity, they may find it difficult to straighten their leg and experience stiffness. The goal of this study is to collect information from participants about the safety and effectiveness of using BOTOX to treat arm and hand spasticity…
This study is to collect information about the symptoms and treatments of patient who have severely clogged arteries and to learn about their outcomes at one year. If you choose to be part of this research, we will ask you to be involved in five interviews with study staff. Each interview will take about 30 minutes of your time and we will contact you…
Abnormal muscle tightness -known as spasticity- in the arm and hand can happen when a child has cerebral palsy. If your child has spasticity, they may find it difficult to straighten their hand and/or arm and experience stiffness. The goal of this study is to collect information from participants about the safety and effectiveness of using BOTOX to treat…