229 Studies Now Enrolling
Menu
Search
Medical Condition
- Show all (1226)
- Addiction (16)
- Allergy, Asthma, & Immunology (12)
- All of Us Research Program - NIH (1)
- Autoimmune Disorders (28)
- Blood Disorders (18)
- Bone & Muscle (10)
- Cancer (100)
- Child Development (4)
- COVID-19 (Coronavirus) (36)
- Critical Illness (1)
- Diabetes (22)
- Ear, Nose and Throat (12)
- Endocrine & Metabolic Disease (13)
- Eye (7)
- Gastrointestinal and Digestive Diseases (26)
- Hair and Skin Disorders (3)
- Headaches (5)
- (-) Healthy Volunteers (188)
- Heart Disease (129)
- Infectious Disease (50)
- Insomnia (3)
- Kidney Disease (12)
- (-) Liver Disease (55)
- Lung Disease (31)
- Meniere's Disease (1)
- Neurological Disorders (125)
- Nutrition (5)
- Obesity (10)
- Obstetrics & Gynecology (56)
- Pain Management (1)
- Pediatrics (97)
- Psychiatric Disorders (67)
- Rehabilitation (9)
- Stroke (7)
- Surgery (7)
- Transplant (46)
- Urology (3)
- Vascular Conditions (10)
Displaying 201 - 243 of 243
Condition: Healthy Volunteers
Investigator: Marc Richmond, MD
Status: Closed
Patients with hypoplastic left heart syndrome and other single right ventricle lesions who have undergone the Fontan procedure have a high risk of neurodevelopmental disorders that affect quality of life and adulthood employment. This study will leverage the ongoing National Heart, Lung, and Blood Institute (NHLBI)-funded Single Ventricle Reconstruction…
Condition: Liver Disease / Hepatitis
Investigator: Elizabeth Verna, MD
Status: Closed
The purpose of this study is to evaluate the effectiveness, safety, and tolerability of study drugs Sofosbuvir, Velpatasvir and GS-9857 in comparison to Sofosbuvir and Velpatasvir in patients infected with HCV. Information about any side effects that may occur will also be collected.
Condition: Healthy Volunteers
Investigator: Sharon Oberfield, MD
Status: Closed
We are recruiting boys between 3-9 years old and girls between 3-8 years old to participate in a research study. Children who would like to participate must be healthy and not showing signs of puberty. The goal of the study is to understand the relationship between early body development, metabolism (sugars and fats processing), and the saliva microbiome (…
Condition: Healthy Volunteers
Investigator: Jeffrey Miller, MD
Status: Closed
The purpose of this study is to use Positron Emission Tomography (PET) to identify changes in brain chemistry that may cause an episode of depression. This study will be carried out in approximately 30 subjects. PET is a technique that provides "pictures" of chemical connections in the brain by injecting and monitoring a radioactive substance. In…
Condition: Liver Disease / MASH (formerly NASH)
Investigator: Elizabeth Verna, MD
Status: Closed
This is a 5-year, longitudinal, observational study of patients with NAFL or NASH designed to specifically address important clinical questions that remain incompletely answered from registration trials. The main purpose of this research study is to collect and study information on patients with NAFLD/NASH.The goal of this study is to observe any treatment…
Condition: Healthy Volunteers
Investigator: Paula Castano, MD, MPH
Status: Closed
Do You Have a Mirena IUD? You may qualify for a study on the extended use of the Mirena IUD! You may qualify if you are 18 to 33 years old and had your Mirena placed in 2013. Compensation available for time and effort. Find out if you qualify!
Condition: Healthy Volunteers
Investigator: William Whang
Status: Closed
The purpose of this study is to evaluate the performance of a remote patient monitoring device against more established wired monitoring devices during common activities and low to moderate exercise.The goal of this study is to determine how the Zephyr BioPatch will work compared to more established wired monitoring devices. This study involves one visit,…
Condition: Healthy Volunteers
Investigator: Jeffrey Shaman, PhD
Status: Closed
You are invited to participate in a study that seeks to understand how respiratory virus infections affect human hosts at various stages of symptomology and predict future wellness states using biophysical measurements from a smartwatch. The goals are to identify biomarkers predictive of symptom outcome and develop early wellness prediction models. The…
Condition: Healthy Volunteers
Investigator: Jonathan Posner, MD
Status: Closed
Children with Attention-Deficit/Hyperactivity Disorder (ADHD) are typically treated with two types of medications: stimulants and non-stimulants. These medications work in different ways to treat ADHD symptoms, but we do not fully understand the brain mechanisms underlying the medications' effects. This study will use MRI scanning to look at changes in…
Condition: Liver Disease
Investigator: Elizabeth Verna, MD
Status: Closed
If you have primary biliary cholangitis (PBC), previously referred to as primary biliary cirrhosis, you may qualify for a clinical research study. In this study, doctors are trying to learn more about the effectiveness and safety of an investigational drug called seladelpar for patients with PBC. The ENHANCE clinical research study is enrolling patients who…
Condition: Liver Disease
Investigator: Robert Brown, MD, MPH
Status: Closed
The primary objective of the study is to evaluate safety and effectiveness of ELAD with respect to overall survival of subjects with a clinical diagnosis of alcohol-induced liver decompensation (ALID). Subjects will be randomly assigned to receive either standard of care treatment for ALID plus treatment with the ELAD system or standard of care treatment…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, MD
Status: Closed
We are working on a new HIV vaccine study that builds on past success and other ongoing studies. This new study is called HVTN 120 and is testing a vaccine for HIV prevention. The Thai Trial has been the only study where the vaccines were partially protective in preventing HIV. We learned a lot from that study, and are now improving on next generation of…
Condition: Healthy Volunteers
Investigator: Brooke Aggarwal, EdD, MS, FAHA
Status: Closed
This study is active but is no longer enrolling new subjects.
Condition: Healthy Volunteers
Investigator: Moise Desvarieux, MD, PhD
Status: Closed
We are looking for people ages 65 and older to help us evaluate if an investigational drug improves muscle function, which can reduce risk of falls and fractures. To be considered for the study, you: 1. Must complete a pre-screening phone interview to assess your eligibility 2. If you are eligible, you will be invited to attend an in-person appointment at…
Condition: Healthy Volunteers
Investigator: Karen Marder, MD, MPH
Status: Closed
This study is recruiting people who have a family history of a neurodegenerative diseases, such as Alzheimer's disease or other form of dementia including frontotemporal dementia and prion disease, who are interested in doing predictive genetic testing. Participants will complete questionnaires prior to testing and then 1 month and 6 months after…
Condition: Liver Disease / Hepatitis
Investigator: Elizabeth Verna, MD
Status: Closed
The purpose of this study is to evaluate the efficacy, safety, and tolerability of SOF/VEL/GS- 9857 FDC in patients infected with Hepatitis C (HCV), and previously treated unsuccessfully. Information about any side effects that may occur will also be collected.
Condition: Healthy Volunteers
Investigator: Kimberly Morel, MD
Status: Closed
This clinical study is being conducted for research purposes. The study cream, SD-101 (Zorblisa), has allantoin as the active ingredient and is being investigated for the treatment of the skin lesions which occur in patients with Epidermolysis Bullosa. The purpose of this clinical study is to study the effectiveness and safety of SD-101 (Zorblisa) in…
Condition: Healthy Volunteers
Investigator: Richard Sloan, PhD
Status: Closed
The purpose of this research study is to determine whether ambulatory monitoring of blood pressure measured by a finger touch blood pressure monitor is a viable approach to measuring blood pressure in the field. A secondary aim is to determine whether the finger touch blood pressure monitor is influenced by individual differences in current stress levels…
Condition: Healthy Volunteers
Investigator: Paula Castano, MD, MPH
Status: Closed
Columbia University is conducting a contraceptive clinical trial looking at two intrauterine devices, one of which is investigational. Pre-menopausal women ages 16-40 who are generally healthy, sexually active, at risk for pregnancy, and are not at risk for sexually transmitted infections may qualify.
Condition: Healthy Volunteers
Investigator: Eldad Hod, MD
Status: Closed
This study is for healthy volunteers. Volunteers who agree to be part of this research will be requested to donate up to 4 tube(s) of blood (approximately 4 teaspoons). The blood will be tested for 5 standard clotting assays. Volunteers will be asked to fill out a questionnaire as well. Compensation for completion of this study is $20.
Condition: Liver Disease
Investigator: Julia Wattacheril, MD, MPH
Status: Closed
This is a randomized, double-blinded, placebo-controlled phase 2 study. The purpose of this study is to evaluate the safety and efficacy of Saroglitazar magnesium 2 mg and 4mg versus placebo in the treatment of subjects with Primary Biliary Cholangitis. The research study consists of a Screening Phase (Visits 1 and 2) that lasts up to 42 days, a Treatment…
Condition: Healthy Volunteers
Investigator: Julia Wynn
Status: Closed
This study is evaluating genomic screening in Ashkenazi Jewish and Hispanic communities. Genomic screening is done by collecting a blood sample and looking at a person's genes to learn if they are at high risk for certain health problems like cancer or heart disease or are at risk to have a child with a genetic condition. The study is designed to…
Condition: Liver Disease / Hepatic Encephalopathy
Investigator: Robert Brown, MD, MPH
Status: Closed
The purpose of this study is to compare the time to onset of an episode of overt HE, in subjects with previously demonstrated overt HE after treatment with rifaximin 550 mg BID and lactulose, or rifaximin 550 mg BID. Subjects will be screened to confirm eligibility into the study. Once confirmed, subjects will begin the treatment phase and will be randomly…
Condition: Healthy Volunteers
Investigator: Eldad Hod, MD
Status: Closed
One of the consequences of donating blood is iron deficiency. In this study, we will screen healthy frequent blood donors for iron deficiency. We will enroll iron deficient donors and randomize them to intravenous iron treatment or placebo in order to determine whether iron deficiency has any harmful effects on the blood supply and the donors themselves.
Condition: Healthy Volunteers
Investigator: Loren Gianini, PhD
Status: Closed
The goal of this study is to better understand why some people have managed to lose weight and keep it off while others have not. We are recruiting people who have lost weight and kept it off as well as healthy non-dieters with overweight or obesity who are not trying to lose weight. Study participation involves computer tasks, brain imaging, and eating a…
Condition: Healthy Volunteers
Investigator: Blandine Laferrere, MD, PhD
Status: Closed
This pilot study is designed to examine the effect of a novel type of lifestyle intervention, administered via a smartphone app, on weight loss and improvement of metabolic health in individuals with overweight and/or obesity. A mobile application will be used to document eating behavior through photos. In addition, participants will receive personalized…
Condition: Liver Disease / Hepatic Encephalopathy
Investigator: Robert Brown, MD, MPH
Status: Closed
The purpose of this study is to find out how doctors describe hepatic encephalopathy episodes in patients medical records in the course of their regular practice. The aim of the study is simply to collect information from their medical records about how their episodes of overt hepatic encephalopathy are described. There is nothing that will be required of…
Condition: Healthy Volunteers
Investigator: Sharon Wardlaw, MD
Status: Closed
This 2-phase study aims to explore ways to predict who will respond well to the FDA approved weight loss drug lorcaserin and to understand the mechanisms that develop which limit drug efficacy. Subjects will be recruited for a 5-week crossover study (phase 1) with lorcaserin and placebo followed by treatment with lorcaserin for 24 weeks (phase 2). Phase 1…
Condition: Healthy Volunteers
Investigator: Yuval Neria, PhD
Status: Closed
Columbia University Medical Center is presently recruiting healthy individuals to participate in an fMRI research study. For your participation, you will receive up to $270 and an opportunity to advance research in the area of trauma and PTSD. This study involves two visits.
Condition: Healthy Volunteers
Investigator: Julie Franks, PhD
Status: Closed
Almost 40,000 people get HIV in the U.S. each year and almost all infections occur via sexual contact, especially male-to-male contact. The number of new infections has decreased slightly each year; however, we need other HIV prevention tools, including an effective HIV vaccine, to better protect people from HIV infection. An HIV vaccine is the best long-…
Condition: Healthy Volunteers
Investigator: Micaela Martinez, PhD
Status: Closed
This study involves wearing a small light sensor on a lanyard and a temperature sensor in a wristband for one week in the summer, fall, winter and spring. The study will span 9 months. Participants will also be asked to fill out a daily questionnaire during those weeks. $30/week compensation or $120 in total for participation.
Condition: Healthy Volunteers
Investigator: Elizabeth Shane, MD
Status: Closed
Osteoporotic fractures affect the lives of 1.5 million Americans each year. Imaging tests, such as bone density, are used to predict fracture risk and to help guide therapy for fracture prevention. In this study we are validating a high-resolution, three-dimensional scanner with the overall goal of improving the diagnosis of bone diseases.
Condition: Healthy Volunteers
Investigator: Rebecca Schnall, PhD, RN
Status: Closed
Take the Online Men's Health Survey (OMHS) today! Human Immunodeficiency Virus (HIV) and syphilis disproportionately affect men who have sex with men (MSM); however, this phenomenon is not well understood and is understudied in the United States. The OMHS study is being performed to help improve STI prevention and treatment services in the United…
Condition: Liver Disease
Investigator: Elizabeth Verna, MD
Status: Closed
The purpose of this study is to test a drug called GSK2330672 that is not yet approved for doctors to prescribe for patients who have a condition called primary biliary cholangitis (PBC) which has caused moderate to severe pruritus, or itching, in parts or all of the body. The objective is to find out if the drug can help to decrease the itchiness that…
Condition: Liver Disease
Investigator: Julia Wattacheril, MD, MPH
Status: Closed
This study is for patients with non-alcoholic steatohepatitis (NASH) fibrosis in which there is too much fat in the liver causing inflammation and fibrosis. This condition is similar to the type of liver damage that occurs from too much alcohol use, but is not primarily caused by alcohol use. The main purpose of the study is to test whether a drug called…
Condition: Liver Disease
Investigator: Julia Wattacheril, MD, MPH
Status: Closed
NASH is a liver disease associated with inflammation and liver cell injury visible under a microscope with a liver biopsy. This condition may lead to advanced fibrosis and cirrhosis and deserves serious medical management. Once cirrhosis has developed, the serious complications of liver disease may occur, including liver failure. NASH might also lead to…
Condition: Liver Disease / Cirrhosis of the Liver
Investigator: Robert Brown, MD, MPH
Status: Closed
The purpose of this study is to evaluate the efficacy of the drug OCR-002 for the treatment of an acute hepatic encephalopathy episode in cirrhotic patients requiring hospitalization. Subjects who have been recently hospitalized will potentially receive OCR-002 via infusion on top of their standard care for 5 days. Patients will be assessed 24-hours after…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, MD
Status: Closed
We are looking for healthy, HIV-negative individuals 18 to 50 years old who are interested in our studies that test antibodies for HIV prevention. Antibodies are one of the natural ways that our bodies fight or prevent infection. We are testing an antibody called VRC07-523LS against HIV. We will ask you to complete a brief questionnaire to find out if you…
Condition: Healthy Volunteers
Investigator: Adam Brickman, PhD
Status: Closed
This study is associated with the Alzheimer's Disease Research Center (ADRC) at Columbia University. The study seeks to understand changes in the way the brain's structure and function are related to age, and the risk of developing memory problems, Alzheimer's disease (AD), and dementia. The study will use magnetic resonance imaging (MRI) to…
Condition: Healthy Volunteers
Investigator: Sumit Mohan, MD
Status: Closed
We are seeking your opinions regarding different organ donation policies, via a 5-10 minute survey; responses are all anonymous. Everyone who completes the survey will have the option to enter a draw for a $5 gift card.
Condition: Healthy Volunteers
Investigator: Erika Berman-Rosenzweig, MD
Status: Closed
This research study is being conducted to study pulmonary hypertension and right heart dysfunction based on clinical, imaging, physiological and pathological characteristics. We hope to develop a new classification system and new methods to diagnose and treat pulmonary hypertension. Diagnostic testing includes (listed subsequently): full medical work-up,…
Condition: Healthy Volunteers
Investigator: Stephen Arpadi, MD, MS
Status: Closed
We are seeking healthy volunteers (HIV-negative) for a study seeing if HIV is associated with faster biological aging among older African American adults, whether faster biological age is related to health conditions that typically occur in older people and whether these conditions might be due to stress or over-activity of certain parts of the immune…
Condition: Healthy Volunteers
Investigator: Daphna Shohamy, PhD
Status: Closed
The Learning Lab at Columbia University is conducting computer based behavioral studies to address fundamental questions regarding the nature of learning, memory, and decision making. Specifically, we will use behavioral methods to investigate the extent to which learning, memory and decision making may be modulated by factors such as novelty, trial-by-…