338 Studies Now Enrolling
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Displaying 201 - 224 of 224
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Closed
The overall goal of this project is to determine whether short sleep duration is a risk factor for cardiovascular disease in women. We are currently looking for healthy, non-smoking women to participate in a sleep study. You must be willing to come to Columbia University Medical Center once a week for two 6-week periods and regularly sleep at least 7-9…
Condition: Healthy Volunteers
Investigator: Suzanne Lewis, MD
Status: Closed
While optical colonoscopy (OC) is considered the gold standard for colorectal cancer screening, there are alternative approaches to visualization of the colon. Participants will receive screening by either colon capsule endoscopy (CCE) and computed tomographic colonography (CTC). They will be instructed to follow a detailed colon preparation regimen prior…
Condition: Healthy Volunteers / Exercise
Investigator: Richard Sloan, PhD
Status: Closed
This study focuses on the effects of aerobic conditioning on cardiovascular function and inflammatory response. Eligible participants will complete an exercise stress test, laboratory visit, and cognitive testing session at three specific time points over the course of the study. Once the initial set of appointments is complete, participants are randomly…
Condition: Healthy Volunteers
Investigator: Jonathan Posner, MD
Status: Closed
Children with Attention-Deficit/Hyperactivity Disorder (ADHD) are typically treated with two types of medications: stimulants and non-stimulants. These medications work in different ways to treat ADHD symptoms, but we do not fully understand the brain mechanisms underlying the medications' effects. This study will use MRI scanning to look at changes in…
Condition: Cancer / Solid Tumors
Investigator: Mark Stein, MD
Status: Closed
The purpose of this study is to test the safety, tolerability, and effectiveness (how well these drugs work together) of NKTR-214 given in combination with KEYTRUDA or TECENTRIQ. We want to find out what effects, good or bad, the study drug has on the body and cancer when combined with KEYTRUDA or TECENTRIQ. The study will recruit participants at least 18…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, MD
Status: Closed
We are working on a new HIV vaccine study that builds on past success and other ongoing studies. This new study is called HVTN 120 and is testing a vaccine for HIV prevention. The Thai Trial has been the only study where the vaccines were partially protective in preventing HIV. We learned a lot from that study, and are now improving on next generation of…
Condition: Healthy Volunteers
Investigator: Jeffrey Miller, MD
Status: Closed
The purpose of this study is to use Positron Emission Tomography (PET) to identify changes in brain chemistry that may cause an episode of depression. This study will be carried out in approximately 30 subjects. PET is a technique that provides "pictures" of chemical connections in the brain by injecting and monitoring a radioactive substance. In…
Condition: Healthy Volunteers
Investigator: Loren Gianini, PhD
Status: Closed
The goal of this study is to better understand why some people have managed to lose weight and keep it off while others have not. We are recruiting people who have lost weight and kept it off as well as healthy non-dieters with overweight or obesity who are not trying to lose weight. Study participation involves computer tasks, brain imaging, and eating a…
Condition: Cancer / Solid Tumors
Investigator: Naiyer Rizvi, MD
Status: Closed
This study is an open-label, multicenter phase 1/2 study. The study is designed in two parts, the first is designed to evaluate the safety of the study drug ulocuplumab in combination with nivolumab in subjects with small cell lung cancer (SCLC) and pancreatic adenocarcinoma (PAC). Subjects will receive a low dose of ulocuplumab in combination with…
Condition: Healthy Volunteers
Investigator: Carolyn Westhoff, MD
Status: Closed
Tired of having to remember to take your birth control? If you are a woman between the ages of 18 and 35, are pre-menopausal, sexually active and do NOT wish to become pregnant, you are invited to see if you may qualify for a research study. The purpose of this research study is to test the effectiveness of an investigational contraceptive vaginal ring. If…
Condition: Healthy Volunteers
Investigator: William Whang
Status: Closed
The purpose of this study is to evaluate the performance of a remote patient monitoring device against more established wired monitoring devices during common activities and low to moderate exercise.The goal of this study is to determine how the Zephyr BioPatch will work compared to more established wired monitoring devices. This study involves one visit,…
Condition: Healthy Volunteers
Investigator: Blandine Laferrere, MD, PhD
Status: Closed
This pilot study is designed to examine the effect of a novel type of lifestyle intervention, administered via a smartphone app, on weight loss and improvement of metabolic health in individuals with overweight and/or obesity. A mobile application will be used to document eating behavior through photos. In addition, participants will receive personalized…
Condition: Cancer / Solid Tumors
Investigator: Gulam Manji, MD, PhD
Status: Closed
GSK3145095 inhibits receptor interacting protein 1 (RIP1) which may affect your immune systems response (ability to fight) to your cancer. GSK3145095 is not yet FDA approved for use in humans. This study is the first time that GSK3145095 is being given to people. This research study is being done to learn more about your cancer and if GSK3145095 can…
Condition: Cancer / Solid Tumors
Investigator: Richard Carvajal, MD
Status: Closed
This is a Phase 1 multiple dose, dose escalation trial in patients with advanced solid tumors who have failed or cannot tolerate standard therapies. Your study doctor has determined that you have an advanced cancer (solid tumor). You are invited to take part in this research study. This study has two parts. In Part 1, the dose escalation portion, the…
Condition: Healthy Volunteers
Investigator: Julie Franks, PhD
Status: Closed
Almost 40,000 people get HIV in the U.S. each year and almost all infections occur via sexual contact, especially male-to-male contact. The number of new infections has decreased slightly each year; however, we need other HIV prevention tools, including an effective HIV vaccine, to better protect people from HIV infection. An HIV vaccine is the best long-…
Condition: Cancer / Solid Tumors
Investigator: Richard Carvajal, MD
Status: Closed
The main purpose of this study is to determine the best dose of MEDI0562 in combination with durvalumab, and MEDI0562 in combination with tremelimumab, that is safe and tolerable in subjects with advanced solid tumors.
Condition: Healthy Volunteers
Investigator: Paula Castano, MD, MPH
Status: Closed
Do You Have a Mirena IUD? You may qualify for a study on the extended use of the Mirena IUD! You may qualify if you are 18 to 33 years old and had your Mirena placed in 2013. Compensation available for time and effort. Find out if you qualify!
Condition: Healthy Volunteers
Investigator: Brooke Aggarwal, EdD, MS, FAHA
Status: Closed
This study is active but is no longer enrolling new subjects.
Condition: Healthy Volunteers
Investigator: Rebecca Schnall, PhD, RN
Status: Closed
Take the Online Men's Health Survey (OMHS) today! Human Immunodeficiency Virus (HIV) and syphilis disproportionately affect men who have sex with men (MSM); however, this phenomenon is not well understood and is understudied in the United States. The OMHS study is being performed to help improve STI prevention and treatment services in the United…
Study of VX15/2508 in Children, Adolescents, or Young Adults with Recurrent or Relapsed Solid Tumors
Condition: Cancer / Solid Tumors
Investigator: Luca Szalontay, MD
Status: Closed
This is a Phase 1/2 multicenter study of VX15/2503 in pediatric patients and young adults with solid tumors which have come back or have not responded to standard therapy. The study treatment is considered experimental because VX15/2503 is not approved by the United States (US) Food and drug Administration (FDA) for treating pediatric patients and young…
Condition: Healthy Volunteers
Investigator: Eldad Hod, MD
Status: Closed
One of the consequences of donating blood is iron deficiency. In this study, we will screen healthy frequent blood donors for iron deficiency. We will enroll iron deficient donors and randomize them to intravenous iron treatment or placebo in order to determine whether iron deficiency has any harmful effects on the blood supply and the donors themselves.
Condition: Healthy Volunteers
Investigator: Kimberly Morel, MD
Status: Closed
This clinical study is being conducted for research purposes. The study cream, SD-101 (Zorblisa), has allantoin as the active ingredient and is being investigated for the treatment of the skin lesions which occur in patients with Epidermolysis Bullosa. The purpose of this clinical study is to study the effectiveness and safety of SD-101 (Zorblisa) in…
Condition: Healthy Volunteers
Investigator: Sumit Mohan, MD
Status: Closed
We are seeking your opinions regarding different organ donation policies, via a 5-10 minute survey; responses are all anonymous. Everyone who completes the survey will have the option to enter a draw for a $5 gift card.
Condition: Cancer / Solid Tumors
Investigator: Gary Schwartz, MD
Status: Closed
The primary purpose of this research study is to evaluate the safety, tolerability and maximum tolerated dose of BAY 1143572. Moreover, concentrations of BAY 1143572 as well as of biomarker proteins may provide information about the effects of BAY 1143572, will be determined in blood and tumor tissue.
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