235 Studies Now Enrolling
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Displaying 1 - 49 of 49
Condition: COVID-19 (Coronavirus)
Investigator: Andrew Einstein, MD
Status: Currently Recruiting
We are seeking patients that have had a pre-COVID heart CT scan (Coronary Computed Tomography Angiography) that was performed at Columbia University Irving Medical Center/NewYork-Presbyterian Hospital before March of 2020. For this study, half of patients will be required to have had COVID-19 symptoms (e.g., fever, cough, shortness of breath) and would have…
Condition: Neurological Disorders / Neuromuscular
Investigator: Thomas Brannagan, MD
Status: Currently Recruiting
The purpose of this study is to evaluate the safety, tolerability and effectiveness of VX-548 in participants with pain due to Diabetic Peripheral Neuropathy (DPN). To be in this study you must have DPN and be 18 through 80 years of age, inclusive, with presence of bilateral pain in lower extremities due to DPN for at least 1 year.
Condition: Neurological Disorders / Neuromuscular
Investigator: Thomas Brannagan, MD
Status: Currently Recruiting
This is a Phase 3, randomized, double blind, study evaluating efficacy and safety of riliprubart versus intravenous immunoglobulin (IVIg) in participants with chronic inflammatory demyelinating polyneuropathy. Overall the study will last about 109 weeks (2 years). Participants must be 18 years old at the time of signing the informed consent form.
Condition: Neurological Disorders / Neuromuscular
Investigator: Matthew Harms, MD
Status: Currently Recruiting
This program provides family members of individuals with familial ALS the opportunity to contribute to research focused on learning more about why motor neuron degeneration begins and how or why it progresses. This study provides genetic counseling and testing to help participants understand and manage their risk and determine if they want to learn their…
Condition: COVID-19 (Coronavirus)
Investigator: Melissa Stockwell, MD, MPH
Status: Currently Recruiting
Help us to better understand the long term effects of COVID. If you or your child has had COVID, or is feeling the long term effects of COVID, you might be able to help us understand more about it and treat it. Even if you or your child has never had COVID, you might be able to help. We are seeking volunteers who are under 25 to join the NIH RECOVER…
Condition: Neurological Disorders / Neuromuscular
Investigator: Clark Smith, MD
Status: Currently Recruiting
The purpose of this research is to study whether Discogen's non-invasive, low-intensity pulsed ultrasound treatment can help reduce pain for people with leg pain and low back pain. Eligible participants will be randomized into either a Discogen treatment group or a sham control group. All participants will be asked to come to the Columbia University…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Currently Recruiting
We want to assess the baseline and cumulative seroprevalence of SARS-CoV-2 using serological and molecular assays. We will also administer a survey. Findings from this study will inform; 1) our understanding of changing epidemiology of COVID-19; 2) use of serological assays and testing algorithms, and 3) approaches to managing psychosocial stress in the…
Condition: COVID-19 (Coronavirus)
Investigator: Deborah Theodore, MD
Status: Currently Recruiting
This is a study for people with symptoms of long COVID. We are looking for people over the age of 18 who are interested in participating in a study to understand whether a mindfulness meditation intervention can help improve symptoms of long COVID. Study participation lasts 6 months and is fully remote.
Condition: COVID-19 (Coronavirus)
Investigator: Michael Yin, MD
Status: Currently Recruiting
We are seeking volunteers who have been diagnosed with COVID-19 by a healthcare provider or by lab testing. We are also looking for volunteers who have never tested positive for COVID-19 and have not received a COVID-19 vaccine. The study, also known as C-PIC, will be looking at antibody levels and how long the virus remains in the body. We are also…
Condition: COVID-19 (Coronavirus)
Investigator: Bernard Chang, MD, PhD
Status: Currently Recruiting
The purpose of this study to examine the long-term general psychological symptoms, and identify the predictors of these psychological symptoms. The sustained psychological toll of working in a high-stress environment can have downstream impacts on health. It is therefore important to also consider how psychological factors influence physical health, for…
Condition: COVID-19 (Coronavirus)
Investigator: Jonathan Overdevest, MD, PhD
Status: Currently Recruiting
Our research team at Columbia University is trying to understand the impact of COVID-19 on smell and taste (chemosensory) dysfunction among adult patients from the Greater New York City area. Current areas of study include: 1) Investigation of smell and taste recovery patterns among patients with COVID-19; 2) Studies on how recovery of smell and taste after…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Currently Recruiting
We are looking for individuals over 18 years old who are interested in learning more about COVID-19 prevention research studies. We will ask you to complete a brief questionnaire to find out if you may be eligible for one of our studies. We can then schedule a phone call, teleconference, or in-person education visit so you can learn about the research we do…
Condition: Neurological Disorders / Neuromuscular
Investigator: Darryl De Vivo, MD
Status: Closed
Columbia University is currently enrolling in an Ataluren Study from PTC Therapeutics, called PTC-041. We are looking for 5 year old boys, ambulating, confirmed nonsense mutation DMD and on steroids for at least 12 months. If you would like more information about this please reach out to Ameneh Onativia, Columbia Sr. Clinical Research Coordinator II at 212…
Condition: COVID-19 (Coronavirus)
Investigator: Michael Yin, MD
Status: Closed
A study looking at improving gut health and cognitive symptoms in Long COVID patients. A 4-week study taking a prebiotic (fiber) with a probiotic bacteria (Synbiotic). The study involves 2 in-person study visits which involves online surveys, cognitive testing, blood samples, stool samples, and rectal swab samples. Each completed study visit pays you $80 in…
Condition: COVID-19 (Coronavirus)
Investigator: Elizabeth Oelsner, MD, MPH
Status: Closed
This study is called the COVID-19 Lung Microvascular and Parenchymal Sequelae (LUNG MaPS) Study. The purpose of the study is to learn about the effects of COVID-19 infections on the lungs and heart, and to improve our understanding of why some COVID-19 patients experience ongoing symptoms, or what is often called "long COVID." Hundreds of…
Condition: Neurological Disorders / Neuromuscular
Investigator: Thomas Brannagan, MD
Status: Closed
The purpose of this study is to Assess Treatments for Painful Diabetic Peripheral Neuropathy (PDPN). To be in this study you must have type II Diabetes Mellitus, PDPN, must be 18 years of age or older, and be able to stop taking some of your current pain medications including pills, creams, patches, marijuana, cannabidiol (CBD) oil, etc. Acetaminophen (…
Condition: COVID-19 (Coronavirus)
Investigator: Dani Dumitriu, MD, PhD
Status: Closed
This study aims to understand the impact of the COVID-19 pandemic on mother and infant health outcomes in pregnant women delivering at NewYork-Presbyterian Morgan Stanley Children's Hospital or Allen Pavilion Hospital. Data will be collected through online surveys, video visits, and electronic health records.
Condition: COVID-19 (Coronavirus)
Investigator: Lenin Grajo, PhD
Status: Closed
We are seeking caregivers like you, caregiving for people who have had COVID-19 and are still experiencing symptoms, to participate in a research study titled A Caregiver Training Program to enhance COVID-19 Patient Readiness. The training program is designed to give you tools to reduce caregiver burden and stress levels. Caregivers must meet the following…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The main purpose of this study is to evaluate the ability of an experimental oral drug called S-217622 to improve the health of people with coronavirus disease 2019 (COVID-19). We also want to see if this study drug is safe, and if this study drug can shorten the time you have COVID-19 symptoms, reduce the amount of virus in the body, and prevent…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
Pfizer and Columbia University Irving Medical Center (CUIMC) are conducting a trial to learn about the safety and effectiveness of an experimental COVID-19 treatment, nirmatrelvir co-packaged with ritonavir, for children with COVID-19 that are at risk of the infection getting worse. Nirmatrelvir/ritonavir has been shown to be effective in fighting SARS-CoV-…
Condition: COVID-19 (Coronavirus)
Investigator: Melissa Stockwell, MD, MPH
Status: Closed
The purpose of this study is to assess the effectiveness of influenza and SARS-CoV-2 vaccines for preventing transmission of infections in households. We are seeking volunteers who have been recently diagnosed with COVID-19 or Influenza virus infection by either rapid diagnostic assay or RT-PCR in the last 7 days and live in a household with at least one…
Condition: COVID-19 (Coronavirus)
Investigator: Philip De Jager, PhD
Status: Closed
We need your help today to gather information about the experience of multiple sclerosis (MS) patients and the general population during the COVID-19 pandemic. Most MS patients take one of over a dozen of medications to control their disease, and these medications alter the immune system. These effects are not as strong as those experienced by patients with…
Condition: COVID-19 (Coronavirus)
Investigator: Marcus Pereira, MD, MPH
Status: Closed
The purpose of this study is to evaluate the safety, immune response, and efficacy of the Moderna mRNA-1273 SARS-CoV-2 vaccine in solid organ transplant recipients and healthy controls. Adult kidney and liver transplant recipients and healthy control participants who are at least 18 years of age will be enrolled. The current study aims to evaluate the…
Condition: COVID-19 (Coronavirus)
Investigator: Ellen Morrison, MD, MPH
Status: Closed
This study enrolls people recently diagnosed with COVID-19, who are not currently in the hospital. The study tests several different investigational medicines to see if they are safe and can help adults with COVID-19 get better, with the goal of quickly determining those that are safe and effective. Help us to rise above COVID-19!
Condition: COVID-19 (Coronavirus)
Investigator: Max O'Donnell, MD, MPH
Status: Closed
The purpose of this study is to test a medication to treat COVID-19 called remdesivir (RDV) that has not yet been approved by the FDA. If you choose to take part in this study, you will continue to receive the standard care for COVID-19. In addition, you will be randomized to either a 5-day or a 10-day treatment with RDV intravenously (by vein in the arm).…
Condition: Neurological Disorders / Neuromuscular
Investigator: Lawrence Honig, MD, PhD
Status: Closed
This is a study for persons with a diagnosis of Progressive Supranuclear Palsy, involving an experimental treatment.
Condition: COVID-19 (Coronavirus)
Investigator: Jennifer Woo Baidal, MD, MPH
Status: Closed
We are interested in studying the health of you and your family. Our study involves completing an online survey about your and your family's health and behaviors, and giving us access to basic health information that includes you and your child's vitals, weight/height, and BMI. You can receive up to $45 in Amazon pay cards for your participation.…
Condition: COVID-19 (Coronavirus)
Investigator: Yael Hirsch-Moverman, PhD
Status: Closed
We are conducting an NIH-funded study to understand how our bodies respond to and recover from the coronavirus and the COVID-19 disease that it causes. If you received a diagnosis of SARS-COV-2 infection and are recovering/or have recovered from COVID-19, you may be eligible to participate in one or more study visits. At each visit you will be asked to…
Condition: COVID-19 (Coronavirus)
Investigator: Eldad Hod, MD
Status: Closed
We are looking for volunteers who have recovered from COVID-19 to donate blood for treatment of others with this virus. Your plasma donation will help up to three people who are currently fighting this virus. Due to the high volume of inquiries, please send an inquiry through RecruitMe by clicking the "Do You Qualify" button. We're receiving…
Condition: COVID-19 (Coronavirus)
Investigator: Melissa Stockwell, MD, MPH
Status: Closed
The C-HEaRT Study: Families with Children Needed for Home-Based COVID-19 Study in Washington Heights/Inwood and Hamilton Heights, NYC. About the study: Weekly, at-home, self-collected nasal swabs (Fall 2020 through Spring 2021), Ship them directly in a prepaid container. Family notified if test positive for COVID-19. Three blood draws for adults (optional…
Condition: Neurological Disorders / Neuromuscular
Investigator: Thomas Brannagan, MD
Status: Closed
Small fiber neuropathy is a painful condition caused by damage to the small nerves in your arms andlegs. This damage causes burning, sharp-stabbing and aching pain, amongst other types of pain. It can be sometimes difficult to know the cause of the damage to the small nerves in your arms and legs. In most cases, treatment for small fiber neuropathy is…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The HIV Vaccine Trials Network (HVTN) and Columbia University Irving Medical Center are doing a study to learn more about SARS-CoV-2 infection and the COVID-19 disease that it can cause. The purpose of this study is to learn more about infection with and recovery from the virus called SARS-CoV-2. Some people know this virus by the name coronavirus. It can…
Condition: COVID-19 (Coronavirus)
Investigator: Jon Giles, MD
Status: Closed
If you currently live in the same household as someone who has tested positive for novel coronavirus (COVID-19), you might be eligible to participate in a trial that will test if a medicine used to prevent malaria, hydroxychloroquine, might reduce the risk of your developing COVID-19 symptoms. COVID-19 is a massive threat to public health worldwide. Post-…
Condition: COVID-19 (Coronavirus)
Investigator: Elisa Konofagou, PhD
Status: Closed
An ultrasound imaging study to assess the long terms effect of past COVID-19 infection in the heart, lung and vessels of recovered patients.
Condition: Neurological Disorders / Neuromuscular
Investigator: Jinsy Andrews, MD, MSc
Status: Closed
The purpose of this research study is to test an investigational drug called NP001. The study will evaluate if NP001 has an effect on slowing the signs and symptoms of your ALS, if there are any side effects, and if there are any medical problems with giving the drug as a solution into your vein (intravenous IV administration). An investigational drug is…
Condition: COVID-19 (Coronavirus)
Investigator: Anca Askanase, MD, MPH
Status: Closed
The purpose of this research study is to determine if chloroquine is effective in health care workers with moderate to high risk of exposure to COVID-19 in preventing symptomatic COVID-19 infections. The time frame for your involvement in the study is 3 months. During month 0, participants will be screened and randomized (like a flip of a coin) to a 3-month…
Condition: COVID-19 (Coronavirus)
Investigator: Deborah Theodore, MD
Status: Closed
The HERO program has two parts: the HERO Registry and the HERO-HCQ Trial. The HERO Registry is asking hundreds of thousands of U.S. healthcare professionals to join, including nurses, therapists, physicians, emergency responders, food service workers, environmental services workers, interpreters, and transporters anyone who works in a setting where people…
Condition: COVID-19 (Coronavirus)
Investigator: David Ho, MD
Status: Closed
Due to the high volume of inquiries, please inquire through RecruitMe. A study to isolate and determine the antibody response in patients who have recovered from COVID-19 for the development of monoclonal antibodies for prevention and treatment of coronavirus infections. We are doing this study to develop antibodies against coronavirus to prevent and treat…
Condition: COVID-19 (Coronavirus)
Investigator: Brian Fallon, MD
Status: Closed
Do you know anyone struggling with anxiety or worry related to any aspect of our current COVID-19 pandemic? This research study is an online low-intensity treatment study which aims to reduce anxiety and enhance resilience in this troubled time. All participants will receive brief anxiety reduction training using cognitive-behavioral strategies. In addition…
Condition: Obstetrics & Gynecology / Preeclampsia
Investigator: Kirsten Cleary, MD
Status: Closed
The purpose of this study is to evaluate the safety and effectiveness of ATryn, for the treatment of early onset preeclampsia (high blood pressure during pregnancy). ATryn is is currently approved by the Food and Drug Administration (FDA) and is used to prevent blood clots from forming in patients who are having surgery or giving birth to a child. Eligible…
Condition: COVID-19 (Coronavirus)
Investigator: Max O'Donnell, MD, MPH
Status: Closed
There are no approved medications to treat COVID-19, a new disease caused by a virus called SARS-CoV-2 that was just identified in late 2019. Some people who become sick with COVID-19 develop a very serious disease. The purpose of this study is to see if Remdesivir (RDV) can improve your health from being sick with COVID-19 infection. The other purpose of…
Condition: COVID-19 (Coronavirus)
Investigator: Max O'Donnell, MD, MPH
Status: Closed
If you want to be a plasma donor please go to (https://recruit.cumc.columbia.edu/clinical_trial/1929). The purpose of this research study is to find out whether antibodies collected from the blood of people, who have been infected with the virus SARS-CoV-2 and recovered from COVID-19, can be used to reduce the risk of severe disease or death in people with…
Condition: Neurological Disorders / Neuromuscular
Investigator: Thomas Brannagan, MD
Status: Closed
This study is designed to test how well an intravenous human immunoglobulin concentrate, IGIV-C (compared with placebo) improves your muscle weakness associated with MG symptoms. A placebo is a medication that looks like the study medication but has no active ingredient. Immunoglobulin is an antibody produced by white blood cells that is used by the immune…
Condition: COVID-19 (Coronavirus)
Investigator: Ellen Morrison, MD, MPH
Status: Closed
We are conducting a CoVPN-funded study to understand if monoclonal antibodies can protect people exposed to SARS-COV-2 from developing the COVID-19 disease that it causes. If you live with someone recently diagnosed with COVID, you may be eligible to participate in one or more study visits. At each visit you will be asked to provide blood, nasal, and urine…
Condition: COVID-19 (Coronavirus)
Investigator: Christine Kim Garcia, MD
Status: Closed
Have you recovered from COVID-19 pneumonia? The FAR-ILD study is designed to detect and study the earliest stages of ILD in at-risk adults, including those who have had a severe viral pneumonia. FAR-ILD is a non-interventional study. This means that FAR-ILD is not involved in testing any new interventions or therapies. The purpose of FAR-ILD is to gather…
Condition: Neurological Disorders / Neuromuscular
Investigator: Thomas Brannagan, MD
Status: Closed
This study is designed to test how well an intravenous human immunoglobulin concentrate, IGIV-C (compared with placebo) improves the ability to taper participant's dose of corticosteroids without causing significant increase in your muscle weakness and worsening MG symptoms. A placebo is a medication that looks like the study medication but has no…
Condition: COVID-19 (Coronavirus)
Investigator: Jessica Justman, MD
Status: Closed
The aim of the study is to assess the safety, efficacy, and immunogenicity of AZD1222 for the prevention of COVID-19. The COVID-19 pandemic has caused major disruption to healthcare systems with significant socioeconomic impacts. Currently, there are no specific treatments available against COVID-19 and accelerated vaccine development is urgently needed. A…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The main purpose of this study is to determine if sarilumab is safe and if it can decrease the amount of time a person has COVID-19 symptoms. Sarilumab (also known as Kevzara ) is considered an investigational drug in this study because it has not been approved for marketing by any health authority for the condition being studied but it has been approved in…
Condition: Neurological Disorders / Neuromuscular
Investigator: Matthew Harms, MD
Status: Closed
The purpose of this study is to look for abnormal genes and gene expression profiles that help determine why a person develops amyotrophic lateral sclerosis (ALS) and related motor neuron diseases (MND) and why their symptoms present and progress with a particular pattern. For up to three years, subjects will be followed every 3 months at the Columbia ALS…