235 Studies Now Enrolling
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Displaying 1 - 50 of 50
Condition: COVID-19 (Coronavirus)
Investigator: Andrew Einstein, MD
Status: Currently Recruiting
We are seeking patients that have had a pre-COVID heart CT scan (Coronary Computed Tomography Angiography) that was performed at Columbia University Irving Medical Center/NewYork-Presbyterian Hospital before March of 2020. For this study, half of patients will be required to have had COVID-19 symptoms (e.g., fever, cough, shortness of breath) and would have…
Condition: Obesity
Investigator: Ilene Fennoy, MD
Status: Currently Recruiting
Bariatric surgery and a once-weekly glucagon-like peptide-1 medicine both cause major weight loss in teens, but their effects on mouth and gut bacteria and on damaged blood fats tied to metabolism are still unknown. This study will collect saliva, stool, and routine blood samples from adolescents before treatment and six months later to see how these…
Condition: Obesity
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are conducting a research study on the effect of high insulin levels on the buildup of excessive liver fat ("fatty liver disease") in people at risk for type 2 diabetes. We are seeking adult volunteers, ages 18-65, who have obesity with a body mass index of 30-45, and have been diagnosed with, or are at risk for, prediabetes and metabolic…
Condition: Obesity
Investigator: Daphna Shohamy, PhD
Status: Currently Recruiting
We are researchers at Columbia studying the learning and decision making. We are looking for participants over the age of 18, who have been prescribed Trizepatide for weight loss. Participants will be asked to complete an MRI scan and play computer games. Participants earn $25 per hour. Help us understand how the GLP-1 agonists affect brain and cognition!
Condition: Obesity
Investigator: Faris Zuraikat, PhD
Status: Currently Recruiting
The purpose of this study is to assess energy balance during two different diet periods.
Condition: Obesity
Investigator: Rudolph Leibel, MD
Status: Currently Recruiting
The Physiology of the Weight Reduced State (POWERS) is a national research study designed to discover and learn what happens to the human body after weight loss and to learn why some people regain their lost weight. Understanding why this happens could help health professionals improve strategies for successful weight loss maintenance after weight loss.…
Condition: Obesity
Investigator: Judith Korner, MD
Status: Currently Recruiting
The purpose of this study is to evaluate if genetic variations are associated with the amount of weight loss with diet and while taking an FDA-approved medication for weight loss. The participation lasts ten months and includes six in-person visits at CUIMC with blood sampling and questionnaires, virtual nutritional counseling, and taking an oral weight…
Condition: COVID-19 (Coronavirus)
Investigator: Melissa Stockwell, MD, MPH
Status: Currently Recruiting
Help us to better understand the long term effects of COVID. If you or your child has had COVID, or is feeling the long term effects of COVID, you might be able to help us understand more about it and treat it. Even if you or your child has never had COVID, you might be able to help. We are seeking volunteers who are under 25 to join the NIH RECOVER…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Currently Recruiting
We want to assess the baseline and cumulative seroprevalence of SARS-CoV-2 using serological and molecular assays. We will also administer a survey. Findings from this study will inform; 1) our understanding of changing epidemiology of COVID-19; 2) use of serological assays and testing algorithms, and 3) approaches to managing psychosocial stress in the…
Condition: Obesity
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are conducting a research study on how insulin controls blood sugar in both healthy people and those at risk of type 2 diabetes. We are seeking adult volunteers, aged 18-65, who have body mass indices either in the lean range (18-25 kg/m2) or in the obesity range (30-45 kg/m2) but who do not have prediabetes or diabetes. Participants will undergo a…
Condition: Obesity
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are recruiting volunteers, aged 18-70, for a research study on the buildup of excessive liver fat ("fatty liver disease") in people with or at risk for type 2 diabetes because their bodies are resistant to the actions of the blood sugar-lowering hormone, insulin. To do this, we seek to temporarily induce or accentuate insulin resistance in 14…
Condition: Obesity
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are seeking adult volunteers with body mass index in the obesity range (30-45 kg/m2) to come in for a single study visit where they answer some health questions and have a small volume of blood drawn (25 cc/1.7 tbsp). We will measure levels of the blood sugar-lowering hormone insulin as well as glucose (sugar), certain fats, and other molecules related…
Condition: COVID-19 (Coronavirus)
Investigator: Deborah Theodore, MD
Status: Currently Recruiting
This is a study for people with symptoms of long COVID. We are looking for people over the age of 18 who are interested in participating in a study to understand whether a mindfulness meditation intervention can help improve symptoms of long COVID. Study participation lasts 6 months and is fully remote.
Condition: COVID-19 (Coronavirus)
Investigator: Michael Yin, MD
Status: Currently Recruiting
We are seeking volunteers who have been diagnosed with COVID-19 by a healthcare provider or by lab testing. We are also looking for volunteers who have never tested positive for COVID-19 and have not received a COVID-19 vaccine. The study, also known as C-PIC, will be looking at antibody levels and how long the virus remains in the body. We are also…
Condition: COVID-19 (Coronavirus)
Investigator: Bernard Chang, MD, PhD
Status: Currently Recruiting
The purpose of this study to examine the long-term general psychological symptoms, and identify the predictors of these psychological symptoms. The sustained psychological toll of working in a high-stress environment can have downstream impacts on health. It is therefore important to also consider how psychological factors influence physical health, for…
Condition: COVID-19 (Coronavirus)
Investigator: Jonathan Overdevest, MD, PhD
Status: Currently Recruiting
Our research team at Columbia University is trying to understand the impact of COVID-19 on smell and taste (chemosensory) dysfunction among adult patients from the Greater New York City area. Current areas of study include: 1) Investigation of smell and taste recovery patterns among patients with COVID-19; 2) Studies on how recovery of smell and taste after…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Currently Recruiting
We are looking for individuals over 18 years old who are interested in learning more about COVID-19 prevention research studies. We will ask you to complete a brief questionnaire to find out if you may be eligible for one of our studies. We can then schedule a phone call, teleconference, or in-person education visit so you can learn about the research we do…
Condition: Gastrointestinal and Digestive Diseases / Barrett's Esophagus
Investigator: Julian Abrams, MD
Status: Closed
This research study will look at a newer treatment option for Barrett's Esophagus (BE) which uses nitrous oxide to freeze unwanted tissue. The most commonly used treatment method is Radiofrequency Ablation (RFA) which uses heat to destroy the pre-cancerous tissue. Nitrous Oxide ablation using the C2 CryoBalloon Focal Ablation System, an FDA-cleared…
Condition: COVID-19 (Coronavirus)
Investigator: Michael Yin, MD
Status: Closed
A study looking at improving gut health and cognitive symptoms in Long COVID patients. A 4-week study taking a prebiotic (fiber) with a probiotic bacteria (Synbiotic). The study involves 2 in-person study visits which involves online surveys, cognitive testing, blood samples, stool samples, and rectal swab samples. Each completed study visit pays you $80 in…
Condition: COVID-19 (Coronavirus)
Investigator: Elizabeth Oelsner, MD, MPH
Status: Closed
This study is called the COVID-19 Lung Microvascular and Parenchymal Sequelae (LUNG MaPS) Study. The purpose of the study is to learn about the effects of COVID-19 infections on the lungs and heart, and to improve our understanding of why some COVID-19 patients experience ongoing symptoms, or what is often called "long COVID." Hundreds of…
Condition: COVID-19 (Coronavirus)
Investigator: Dani Dumitriu, MD, PhD
Status: Closed
This study aims to understand the impact of the COVID-19 pandemic on mother and infant health outcomes in pregnant women delivering at NewYork-Presbyterian Morgan Stanley Children's Hospital or Allen Pavilion Hospital. Data will be collected through online surveys, video visits, and electronic health records.
Condition: COVID-19 (Coronavirus)
Investigator: Lenin Grajo, PhD
Status: Closed
We are seeking caregivers like you, caregiving for people who have had COVID-19 and are still experiencing symptoms, to participate in a research study titled A Caregiver Training Program to enhance COVID-19 Patient Readiness. The training program is designed to give you tools to reduce caregiver burden and stress levels. Caregivers must meet the following…
Condition: Obesity
Investigator: Joshua Cook, MD, PhD
Status: Closed
We're conducting a research study on how much insulin is needed to control blood sugar in people who are made temporarily resistant to insulin's effects. Insulin is the main hormone (chemical signal) that the body uses to lower the levels of sugar in the blood. We are interested in looking at insulin levels because we think that lowering insulin…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The main purpose of this study is to evaluate the ability of an experimental oral drug called S-217622 to improve the health of people with coronavirus disease 2019 (COVID-19). We also want to see if this study drug is safe, and if this study drug can shorten the time you have COVID-19 symptoms, reduce the amount of virus in the body, and prevent…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
Pfizer and Columbia University Irving Medical Center (CUIMC) are conducting a trial to learn about the safety and effectiveness of an experimental COVID-19 treatment, nirmatrelvir co-packaged with ritonavir, for children with COVID-19 that are at risk of the infection getting worse. Nirmatrelvir/ritonavir has been shown to be effective in fighting SARS-CoV-…
Condition: COVID-19 (Coronavirus)
Investigator: Melissa Stockwell, MD, MPH
Status: Closed
The purpose of this study is to assess the effectiveness of influenza and SARS-CoV-2 vaccines for preventing transmission of infections in households. We are seeking volunteers who have been recently diagnosed with COVID-19 or Influenza virus infection by either rapid diagnostic assay or RT-PCR in the last 7 days and live in a household with at least one…
Condition: COVID-19 (Coronavirus)
Investigator: Philip De Jager, PhD
Status: Closed
We need your help today to gather information about the experience of multiple sclerosis (MS) patients and the general population during the COVID-19 pandemic. Most MS patients take one of over a dozen of medications to control their disease, and these medications alter the immune system. These effects are not as strong as those experienced by patients with…
Condition: COVID-19 (Coronavirus)
Investigator: Marcus Pereira, MD, MPH
Status: Closed
The purpose of this study is to evaluate the safety, immune response, and efficacy of the Moderna mRNA-1273 SARS-CoV-2 vaccine in solid organ transplant recipients and healthy controls. Adult kidney and liver transplant recipients and healthy control participants who are at least 18 years of age will be enrolled. The current study aims to evaluate the…
Condition: COVID-19 (Coronavirus)
Investigator: Ellen Morrison, MD, MPH
Status: Closed
This study enrolls people recently diagnosed with COVID-19, who are not currently in the hospital. The study tests several different investigational medicines to see if they are safe and can help adults with COVID-19 get better, with the goal of quickly determining those that are safe and effective. Help us to rise above COVID-19!
Condition: COVID-19 (Coronavirus)
Investigator: Jessica Justman, MD
Status: Closed
The aim of the study is to assess the safety, efficacy, and immunogenicity of AZD1222 for the prevention of COVID-19. The COVID-19 pandemic has caused major disruption to healthcare systems with significant socioeconomic impacts. Currently, there are no specific treatments available against COVID-19 and accelerated vaccine development is urgently needed. A…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The main purpose of this study is to determine if sarilumab is safe and if it can decrease the amount of time a person has COVID-19 symptoms. Sarilumab (also known as Kevzara ) is considered an investigational drug in this study because it has not been approved for marketing by any health authority for the condition being studied but it has been approved in…
Condition: Gastrointestinal and Digestive Diseases / Barrett's Esophagus
Investigator: Julian Abrams, MD
Status: Closed
The purpose of the study is to compare two types of endoscopic treatments in patients with Barretts esophagus (BE) with abnormal cells (dysplasia); radiofrequency ablation (RFA) and hybrid argon plasma coagulation (H-APC). H-APC is a newer technique in the treatment of BE and has not been adequately studied and is not approved by the FDA for routine use.…
Condition: COVID-19 (Coronavirus)
Investigator: Max O'Donnell, MD, MPH
Status: Closed
The purpose of this study is to test a medication to treat COVID-19 called remdesivir (RDV) that has not yet been approved by the FDA. If you choose to take part in this study, you will continue to receive the standard care for COVID-19. In addition, you will be randomized to either a 5-day or a 10-day treatment with RDV intravenously (by vein in the arm).…
Condition: COVID-19 (Coronavirus)
Investigator: Jennifer Woo Baidal, MD, MPH
Status: Closed
We are interested in studying the health of you and your family. Our study involves completing an online survey about your and your family's health and behaviors, and giving us access to basic health information that includes you and your child's vitals, weight/height, and BMI. You can receive up to $45 in Amazon pay cards for your participation.…
Condition: COVID-19 (Coronavirus)
Investigator: Yael Hirsch-Moverman, PhD
Status: Closed
We are conducting an NIH-funded study to understand how our bodies respond to and recover from the coronavirus and the COVID-19 disease that it causes. If you received a diagnosis of SARS-COV-2 infection and are recovering/or have recovered from COVID-19, you may be eligible to participate in one or more study visits. At each visit you will be asked to…
Condition: COVID-19 (Coronavirus)
Investigator: Eldad Hod, MD
Status: Closed
We are looking for volunteers who have recovered from COVID-19 to donate blood for treatment of others with this virus. Your plasma donation will help up to three people who are currently fighting this virus. Due to the high volume of inquiries, please send an inquiry through RecruitMe by clicking the "Do You Qualify" button. We're receiving…
Condition: COVID-19 (Coronavirus)
Investigator: Melissa Stockwell, MD, MPH
Status: Closed
The C-HEaRT Study: Families with Children Needed for Home-Based COVID-19 Study in Washington Heights/Inwood and Hamilton Heights, NYC. About the study: Weekly, at-home, self-collected nasal swabs (Fall 2020 through Spring 2021), Ship them directly in a prepaid container. Family notified if test positive for COVID-19. Three blood draws for adults (optional…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The HIV Vaccine Trials Network (HVTN) and Columbia University Irving Medical Center are doing a study to learn more about SARS-CoV-2 infection and the COVID-19 disease that it can cause. The purpose of this study is to learn more about infection with and recovery from the virus called SARS-CoV-2. Some people know this virus by the name coronavirus. It can…
Condition: COVID-19 (Coronavirus)
Investigator: Jon Giles, MD
Status: Closed
If you currently live in the same household as someone who has tested positive for novel coronavirus (COVID-19), you might be eligible to participate in a trial that will test if a medicine used to prevent malaria, hydroxychloroquine, might reduce the risk of your developing COVID-19 symptoms. COVID-19 is a massive threat to public health worldwide. Post-…
Condition: COVID-19 (Coronavirus)
Investigator: Elisa Konofagou, PhD
Status: Closed
An ultrasound imaging study to assess the long terms effect of past COVID-19 infection in the heart, lung and vessels of recovered patients.
Condition: COVID-19 (Coronavirus)
Investigator: Anca Askanase, MD, MPH
Status: Closed
The purpose of this research study is to determine if chloroquine is effective in health care workers with moderate to high risk of exposure to COVID-19 in preventing symptomatic COVID-19 infections. The time frame for your involvement in the study is 3 months. During month 0, participants will be screened and randomized (like a flip of a coin) to a 3-month…
Condition: COVID-19 (Coronavirus)
Investigator: Deborah Theodore, MD
Status: Closed
The HERO program has two parts: the HERO Registry and the HERO-HCQ Trial. The HERO Registry is asking hundreds of thousands of U.S. healthcare professionals to join, including nurses, therapists, physicians, emergency responders, food service workers, environmental services workers, interpreters, and transporters anyone who works in a setting where people…
Condition: COVID-19 (Coronavirus)
Investigator: David Ho, MD
Status: Closed
Due to the high volume of inquiries, please inquire through RecruitMe. A study to isolate and determine the antibody response in patients who have recovered from COVID-19 for the development of monoclonal antibodies for prevention and treatment of coronavirus infections. We are doing this study to develop antibodies against coronavirus to prevent and treat…
Condition: COVID-19 (Coronavirus)
Investigator: Brian Fallon, MD
Status: Closed
Do you know anyone struggling with anxiety or worry related to any aspect of our current COVID-19 pandemic? This research study is an online low-intensity treatment study which aims to reduce anxiety and enhance resilience in this troubled time. All participants will receive brief anxiety reduction training using cognitive-behavioral strategies. In addition…
Condition: COVID-19 (Coronavirus)
Investigator: Max O'Donnell, MD, MPH
Status: Closed
There are no approved medications to treat COVID-19, a new disease caused by a virus called SARS-CoV-2 that was just identified in late 2019. Some people who become sick with COVID-19 develop a very serious disease. The purpose of this study is to see if Remdesivir (RDV) can improve your health from being sick with COVID-19 infection. The other purpose of…
Condition: COVID-19 (Coronavirus)
Investigator: Max O'Donnell, MD, MPH
Status: Closed
If you want to be a plasma donor please go to (https://recruit.cumc.columbia.edu/clinical_trial/1929). The purpose of this research study is to find out whether antibodies collected from the blood of people, who have been infected with the virus SARS-CoV-2 and recovered from COVID-19, can be used to reduce the risk of severe disease or death in people with…
Condition: Gastrointestinal and Digestive Diseases / Barrett's Esophagus
Investigator: Julian Abrams, MD
Status: Closed
C2 Therapeutics is currently enrolling patients to participate in the Coldplay 3 clinical trial. Coldplay 3 is evaluating the effectiveness of the Coldplay CryoBalloon Focal Ablation System in patients with Barrett's esophagus who have not yet received treatment. Participants will undergo treatment with the Coldplay CryoBalloon Focal Ablation System…
Condition: COVID-19 (Coronavirus)
Investigator: Ellen Morrison, MD, MPH
Status: Closed
We are conducting a CoVPN-funded study to understand if monoclonal antibodies can protect people exposed to SARS-COV-2 from developing the COVID-19 disease that it causes. If you live with someone recently diagnosed with COVID, you may be eligible to participate in one or more study visits. At each visit you will be asked to provide blood, nasal, and urine…
Condition: COVID-19 (Coronavirus)
Investigator: Christine Kim Garcia, MD
Status: Closed
Have you recovered from COVID-19 pneumonia? The FAR-ILD study is designed to detect and study the earliest stages of ILD in at-risk adults, including those who have had a severe viral pneumonia. FAR-ILD is a non-interventional study. This means that FAR-ILD is not involved in testing any new interventions or therapies. The purpose of FAR-ILD is to gather…
Condition: Gastrointestinal and Digestive Diseases / Barrett's Esophagus
Investigator: Julian Abrams, MD
Status: Closed
The purpose of this study is to evaluate a new technique called Wide Area Transepithelial Sample 3-Dimensional Esophageal Biopsy (WATS) with computer assisted method of analysis of brush biopsy. This study will assess whether performing standard biopsies in addition to the WATS brush biopsies identifies more patients with dysplasia than does performing…