236 Studies Now Enrolling
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Displaying 1 - 58 of 58
Condition: Healthy Volunteers
Investigator: Lena Mamykina, PhD
Status: Currently Recruiting
Seeking participants for a study about how individuals prefer to receive nutrition recommendations to support health management and preferences for visualizing health data. Participants may be invited to complete a 60-minute session to answer questionnaires and evaluate different styles of nutritional recommendations. In addition, they may be invited to…
Condition: Healthy Volunteers
Investigator: Steven Kushner, MD, PhD
Status: Currently Recruiting
As an academic medical center, Columbia University is committed to improving patient and population health through research. One way this work is supported is through the Columbia University Biobank (CUB), a secure collection of biological samples and health data that helps researchers better understand disease and develop new treatments. Researchers at…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Currently Recruiting
The overall goal of this project is to determine whether the timing of your meals and sleep influences health. We are looking for healthy adults aged 30 and older to participate in a sleep study. Participants must be willing to keep a written food and sleep record for 7 consecutive days. Participants who complete this study will receive a total compensation…
Condition: Liver Disease / Cirrhosis of the Liver
Investigator: Elizabeth Verna, MD
Status: Currently Recruiting
The purpose of this research study is to determine whether rosuvastatin is safe and can help people living with cirrhosis lead longer, healthier lives. The study drug, rosuvastatin, is investigational, meaning it has not yet been approved for market use for this disease condition by the United States Food and Drug Administration (FDA). Participants will…
Condition: Healthy Volunteers
Investigator: Ronald Silverman, PhD
Status: Currently Recruiting
The Department of Ophthalmology is conducting an NIH-funded study of 3D ultrasound imaging of the eye, including the vitreous and optic nerve. We are interested in normal subjects without eye disease and individuals with vitreous floaters. The total duration of the exam is approximately 30 minutes. Participation is voluntary and no financial compensation is…
Condition: Healthy Volunteers
Investigator: Kiyohito Iigaya, PhD
Status: Currently Recruiting
Our lab is conducting a series of research studies investigating people's memory and decision-making. As a healthy study participant, you will be asked to complete a set of self-report questionnaires probing demographics and personality traits, followed by a number of computer-based tasks. Study participants earn between $15/hour for their time. The…
Condition: Healthy Volunteers
Investigator: Kiyohito Iigaya, PhD
Status: Currently Recruiting
Our lab is conducting a magnetic resonance imaging (fMRI) study to investigate people's memory and decision-making. We are looking for people between the ages of 18 and 60 to be healthy study participants. In this study you will be asked to complete a set of self-report questionnaires probing demographics and personality traits, followed by a number of…
Condition: Liver Disease
Investigator: Giuseppe Cullaro, MD
Status: Currently Recruiting
The DROP-AKI Trial is studying whether droxidopa, an FDA-approved medication for low blood pressure, can help patients with liver cirrhosis who develop kidney problems during hospitalization. Although droxidopa is FDA-approved for certain types of low blood pressure, it is not approved to treat patients with cirrhosis of the liver who develop kidney injury…
Condition: Healthy Volunteers
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are conducting a research study on how insulin controls blood sugar in both healthy people and those at risk of type 2 diabetes. We are seeking adult volunteers, aged 18-65, who have body mass indices either in the lean range (18-25 kg/m2) or in the obesity range (30-45 kg/m2) but who do not have prediabetes or diabetes. Participants will undergo a…
Condition: Healthy Volunteers
Investigator: Daniel Javitt, MD, PhD
Status: Currently Recruiting
The Division of Experimental Therapeutics in conducting a research study to explore how an experimental procedure, known as transcranial interference stimulation (tIS), affects the brain's ability to process visual information, including recognizing faces. The procedures in this study include 1) interviews, 2) behavioral tests of your ability to detect…
Condition: Liver Disease
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are conducting a research study on the effect of high insulin levels on the buildup of excessive liver fat ("fatty liver disease") in people at risk for type 2 diabetes. We are seeking adult volunteers, ages 18-65, who have obesity with a body mass index of 30-45, and have been diagnosed with, or are at risk for, prediabetes and metabolic…
Condition: Healthy Volunteers
Investigator: Brooke Aggarwal, EdD, MS, FAHA
Status: Currently Recruiting
Women ages 40-65 years may be eligible to participate in a survey about their sleep patterns, stress, and risk factors for heart disease. If you are interested or would like more information, please email us at researchgoesredsurvey@gmail.com.
Condition: Healthy Volunteers
Investigator: Keith Diaz, PhD
Status: Currently Recruiting
U.S. Adults spend on average 11 to 12 hours a day sitting. Daily sedentary behavior is strongly associated with the risk of heart disease. The purpose of the BREAK II research study is to answer two questions: (1) How frequently should periods of prolonged sedentary time be interrupted? and (2) What is the appropriate duration or length of time of these…
Condition: Healthy Volunteers
Investigator: Eldad Hod, MD
Status: Currently Recruiting
We are studying the effects of blood donation. If you are considering donating blood at the next school blood drive, please contact us to determine eligibility. You may qualify for participation whether or not you successfully donate blood and you will be compensated monetarily for your time.
Condition: Healthy Volunteers
Investigator: Marla Hamberger, PhD
Status: Currently Recruiting
We are looking for healthy participants. The purpose of this project is to develop a set of word finding or "naming" tests for Bilingual English-Spanish speakers, ages 35-85. The main tasks involve naming pictures of common objects (e.g. broom) or naming items when given a description (e.g. "what children ride to school in"). There are…
Condition: Healthy Volunteers
Investigator: Dritan Agalliu, PhD
Status: Currently Recruiting
The aim of this study is to understand the mechanisms of secondary effects of traumatic brain injury on the blood-brain barrier and to understand the biochemical differences in the blood of people with Alzheimer's disease and the volunteer group. We will compare biochemical blood differences between a healthy group and traumatic brain injury patients…
Condition: Healthy Volunteers
Investigator: Lila Davachi, PhD
Status: Currently Recruiting
The Davachi Lab is currently recruiting to investigate how individuals process and experience everyday events. The current study involves completing two weeks of "daily diary" survey entries that inquire about your daily experiences, such as such as where you went, what emotions you experienced, or what activities you engaged in. This study is…
Condition: Liver Disease
Investigator: Mercedes Martinez, MD
Status: Currently Recruiting
This study is examining how oral vancomycin, an antibiotic sometimes used to treat Primary Sclerosing Cholangitis (PSC), affects the bacteria living in the gut (the microbiome). The study is observational, meaning it does not alter medical care or prescribe treatment-participants will continue their usual therapy as decided by their doctors. The study will…
Condition: Liver Disease
Investigator: Julia Wattacheril, MD, MPH
Status: Currently Recruiting
The purpose of this study is to learn about the causes of non-alcoholic fatty liver disease (NAFLD). This is the most common type of liver disease, affecting millions of people in the United States alone. The incidence of Nonalcoholic Fatty Liver Disease (NAFLD) is very similar to that of obesity, type-2 diabetes, and the metabolic syndrome, suggesting a…
Condition: Liver Disease
Investigator: Mercedes Martinez, MD
Status: Currently Recruiting
This study is evaluating how well odevixibat, an approved medication for Alagille Syndrome (ALGS), works in real-world clinical practice and how safe it is for long-term use. Participants with ALGS who are receiving odevixibat as part of their usual medical care will be followed for about five years. During this time, information from routine clinic visits…
Condition: Liver Disease
Investigator: Gene Im, MD, FAASLD
Status: Currently Recruiting
The purpose of this study is to evaluate the study drug, pemvidutide, as a possible treatment for alcohol associated liver disease or ALD. ALD is a condition in which excessive alcohol use (commonly defined as more than 2 drinks per day for women and 3 drinks per day for men) leads to liver inflammation and damage. Pemvidutide is investigational, meaning…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Currently Recruiting
We are currently looking for healthy, nonsmoking adults ages 40-65 yrs who are dissatisfied with their sleep to participate in a sleep study. Participants should find their sleep not refreshing but not taking external sleep aids. Participants must be willing to eat a specific food for 2 periods of 4 weeks each. Compensation of up to $700 will be provided…
Condition: Healthy Volunteers
Investigator: Sarah Herzog, PhD
Status: Currently Recruiting
We are conducting a study on depression and suicide risk, and participants can earn up to $300 for taking part. Suicide rates in the U.S. are rising, and new treatments are urgently needed. This study focuses on the brain chemical glutamate, which may play an important role in mood and mental health. We will compare glutamate levels at rest and during…
Condition: Healthy Volunteers
Investigator: Jon Freeman, PhD
Status: Currently Recruiting
The Social Cognitive & Neural Sciences Lab at Columbia University's Department of Psychology is conducting a brain imaging study, which will take place over the next 1-3 months. You will be compensated for your time and receive a free video of your brain! We are flexible in scheduling convenient times for you to come in. The study will involve a 2-…
Condition: Healthy Volunteers
Investigator: Julie Herbstman, PhD, MSc
Status: Currently Recruiting
You are invited to participate in a research study to understand how environmental exposures during pregnancy influence the health and development of children. This study will begin at pregnancy and follow your child through age 11. A trained research worker will work with you and your child, administering questionnaires to you and developmental evaluations…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Currently Recruiting
We are currently looking for healthy nonsmokers, ages 18-49yrs who are satisfied with their sleep to participate in a sleep study. Participants should typically sleep 7-9 hours/night without external sleep aids. Participants must be willing to change their sleep schedule for approximately 4 weeks. Compensation of up to $1000 will be provided for completing…
Condition: Healthy Volunteers
Investigator: Catherine Clelland, PhD
Status: Currently Recruiting
This research study aims to obtain a greater understanding of the causes of cognitive decline in Alzheimer's disease. We are currently enrolling male and female participants (ages 55 years and older) with Alzheimer's disease, mild cognitive impairment, or healthy controls. Enrolled participants with undergo a small blood draw (about 8 teaspoons)…
Condition: Healthy Volunteers
Investigator: Richard Francis, MD, PhD
Status: Currently Recruiting
This is a Blood Donor Study being conducted at Columbia University Irving Medical Center - New York Presbyterian Hospital. We are interested in recruiting males between the ages of 18-65 who are of African, Asian, Hispanic, Middle Eastern, or Mediterranean descent. The purpose of this research study is to determine whether genetic factors in your DNA affect…
Condition: Healthy Volunteers
Investigator: A. Benjamin Srivastava, MD
Status: Currently Recruiting
Do you ever wonder how brains work? You can earn compensation for completing a study investigating human brain function by having a brain scan. You can earn up to $220 for your participation.
Condition: Healthy Volunteers
Investigator: Michael Lipton, MD PhD
Status: Currently Recruiting
The Lifespan Study uses neuroimaging, cognitive tests, and genomics to explore how the brain's structure and function change throughout life. We are creating a database of typical brain imaging data to study age-related changes. This database will support research, clinical studies, and the creation of new tools for measuring brain health. The Lifespan…
Condition: Healthy Volunteers
Investigator: Norman Kleiman, PhD
Status: Currently Recruiting
We are seeking female menstruating subjects to determine the level of PFAS present in feminine hygiene products. We will ask subjects to provide both a used and unused tampon to measure levels of these chemicals.
Condition: Healthy Volunteers
Investigator: David Welch
Status: Currently Recruiting
We are seeking subjects for measurements of skin properties using non-invasive devices. Measurements will be made to the forehead and forearm of the participant. These measurements will be performed during a single visit lasting approximately 1 hour.
Condition: Liver Disease
Investigator: Elizabeth Verna, MD
Status: Currently Recruiting
The purpose of this study is to determine if an experimental drug, INT-787, is safe and effective in patients who are hospitalized due to severe alcohol-associated hepatitis. This is a double-blind study, so the study doctors and participants will not know if they are receiving INT-787 or a placebo. Participation will last approximately 3 months. If you…
Condition: Healthy Volunteers
Investigator: Kiyohito Iigaya, PhD
Status: Currently Recruiting
Our lab is conducting a series of research studies investigating people's behavior. We are looking for people between the ages of 18 and 60. As a healthy study participant, you will be asked to complete a set of self-report questionnaires probing demographics and personality traits, followed by a number of computer-based tasks. Study participants earn…
Condition: Liver Disease / Liver Failure
Investigator: Steven Lobritto, MD
Status: Currently Recruiting
TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three-arm clinical trial of immunosuppressive therapy for children with acute liver failure. This is a double-blind study, so the study doctors and participants will not know to which arm the participants are assigned. The study will determine if corticosteroids or equine anti-…
Condition: Healthy Volunteers
Investigator: Philip De Jager, PhD
Status: Currently Recruiting
Genes and Environment in MS (GEMS) is a longitudinal cohort study investigating how genetics and environment can lead to the onset of Multiple Sclerosis. We are recruiting first-degree relatives (siblings, parents, and children) of people who have been diagnosed with MS. This study involves the collection of magnetic resonance imaging (MRI) of the brain,…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Currently Recruiting
We are currently looking for healthy, nonsmoking adults ages 25-65yrs who are dissatisfied with their sleep to participate in a sleep study. Participants should find their sleep not refreshing but not taking external sleep aids. Participants must be willing to eat different foods for two periods of 4 days and undergo testing over a 24-hour period at the…
Condition: Liver Disease
Investigator: Mercedes Martinez, MD
Status: Currently Recruiting
The purpose of this study is to determine whether the investigational drug (maralixibat) is safe and effective in children and participants who have cholestatic liver disease with pruritus (itch) that has been responding to other therapies, and who have no other treatment options.If you have any questions regarding this study, please contact the Transplant…
Condition: Healthy Volunteers
Investigator: Guillermo Horga, MD, PhD
Status: Currently Recruiting
In this study, we are trying to learn more about the symptoms of psychosis, specifically to learn how alterations in the brain may produce certain experiences (including voice hearing or auditory hallucinations) that are common in people with psychosis or schizophrenia. The study involves clinical interviews, computer tests, and magnetic resonance imaging (…
Condition: Healthy Volunteers
Investigator: Julian Agin-Liebes, MD
Status: Currently Recruiting
We are looking for participants for a study on the role of immune response in Parkinsons disease (PD) and Alzheimer's disease (AD). We are inviting people WITH PD, WITH AD, WITH amnestic Mild Cognitive Impairment or WITHOUT PD or AD to come and participate. We will be doing several questionnaires, a motor exam, and a short cognitive assessment, in…
Condition: Healthy Volunteers
Investigator: Scott Small, MD
Status: Currently Recruiting
For over 30 years, The Columbia University Alzheimer's Disease Research Center (ADRC) has worked with thousands of participants who have helped provide important insights into how the brain ages and why Alzheimer's disease may develop. We are actively recruiting adults 65 years of age and older who share our commitment to be part of this…
Condition: Healthy Volunteers
Investigator: Jonathan Overdevest, MD, PhD
Status: Currently Recruiting
The Columbia Otolaryngology Department is interested in understanding how sense of smell relates to memory and neurocognition. Participation will involve answering a series of questionnaires, completing a formal evaluation of your smell with standardized measurements, and complete short smell and memory games. You can participate in this study if you are…
Condition: Healthy Volunteers
Investigator: Patrick Lao, PhD
Status: Currently Recruiting
The purpose of this study is to determine how inflammation is related to changes in the brain that occur during the progression of Alzheimer's disease. If you are eligible for this study, we will ask you to complete 3-4 study visits over the course of about 5 months. Participation includes memory testing, a blood draw, MRI, PET scans, and a lumbar…
Condition: Healthy Volunteers
Investigator: Lila Davachi, PhD
Status: Currently Recruiting
The Davachi Lab is currently running research studies to investigate information processing. These behavioral studies may involve looking at negative, neutral, and positive images on a computer screen (such as objects, faces, or scenes) and/or listening to negative, neutral, and positive auditory sounds (such as tones with varied pitches or human-produced…
Condition: Liver Disease
Investigator: Avesh Thuluvath, MD
Status: Currently Recruiting
The purpose of this study is to learn whether wearable technology and the biometric data (e.g. heart rate, activity level, sleep) collected from it can be useful to detect clinical changes in those with liver disease, so that in the future it may help to prevent complications. The wearable technology that will be utilized in this study is the Oura Ring.…
Condition: Liver Disease
Investigator: Mercedes Martinez, MD
Status: Currently Recruiting
The purpose of this study is to better understand how common and how severe pruritis (itching) is in children and adults under 21 years of age with Primary Sclerosing Cholangitis (PSC). The study involves the completion of two short online surveys. If you have any questions regarding this study, please contact the Transplant Clinical Research Center (TCRC).
Condition: Liver Disease
Investigator: Elizabeth Verna, MD
Status: Currently Recruiting
TARGET-Liver Disease (TARGET-LD) is an observational research study to learn more about adult patients who have been diagnosed with a chronic liver disease (CLD). This includes collecting information about their health and the medications they take to manage their disease. Participation in this study will be approximately 15 years. If you have any questions…
Condition: Healthy Volunteers
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are recruiting volunteers, aged 18-70, for a research study on the buildup of excessive liver fat ("fatty liver disease") in people with or at risk for type 2 diabetes because their bodies are resistant to the actions of the blood sugar-lowering hormone, insulin. To do this, we seek to temporarily induce or accentuate insulin resistance in 14…
Condition: Healthy Volunteers
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are seeking adult volunteers with body mass index in the obesity range (30-45 kg/m2) to come in for a single study visit where they answer some health questions and have a small volume of blood drawn (25 cc/1.7 tbsp). We will measure levels of the blood sugar-lowering hormone insulin as well as glucose (sugar), certain fats, and other molecules related…
Condition: Healthy Volunteers
Investigator: Pamela Freda, MD
Status: Currently Recruiting
Growth hormone and insulin-like growth-factor 1 (IGF-1) are two hormones that are very important to human growth and metabolism. In disorders of GH and IGF-1 excess and deficiency, significant growth and metabolic abnormalities can develop. This study investigates the effects of GH on the appetite-stimulating hormone AgRP (agouti-related peptide) and the…
Condition: Healthy Volunteers
Investigator: Yufeng Shen, PhD
Status: Currently Recruiting
Study examining the genetic causes of birth defects
Condition: Healthy Volunteers
Investigator: Muredach Reilly, MD
Status: Currently Recruiting
As an academic medical center, we are always working to improve patient and population health. One way that research is supported here is through the Columbia University Biobank (CUB). A biobank is a collection of biological samples and health data gathered during a patient's medical care. Participants in a biobank help researchers find treatments and…
Condition: Healthy Volunteers
Investigator: Daniel Wolpert, PhD
Status: Currently Recruiting
The Sensorimotor Learning Lab at Columbia University is conducting behavioral studies of how our brains control movement. We are looking for volunteers to take part in experiments involving moving in virtual reality, interacting with robotic interfaces and other movement tasks. All the experiments are noninvasive and have been approved by the Columbia IRB.…
Condition: Healthy Volunteers
Investigator: David Brenner, PhD
Status: Currently Recruiting
The purpose of this study is to use blood from healthy people to develop a test to see if people have been exposed to radiation. Between 2 and 3 tablespoons of blood will be drawn from your arm. The blood will be tested with radiation in our laboratory at the Center for Radiological Research at the Columbia University Irving Medical Center. We will measure…
Condition: Healthy Volunteers
Investigator: Philip De Jager, PhD
Status: Currently Recruiting
The Snapshot study aims to understand brain and spinal cord aging in healthy individuals and individuals with multiple sclerosis (MS). We aim to identify new tools that will help us to achieve successful brain aging in the general population and in people with an underlying autoimmune disease. A critical aspect of this study is that we are looking for…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Currently Recruiting
We are looking for individuals 18 to 65 years old who are interested in learning more about HIV prevention and biomedical research studies. We will ask you to complete a brief questionnaire to find out if we can schedule you for a one-on-one, 1.5-hour education visit to learn about the research we do. The education visit will help you decide if you want to…
Condition: Healthy Volunteers
Investigator: Philip De Jager, PhD
Status: Currently Recruiting
The purpose of this study is to establish a collection of biological fluids and associated data from healthy individuals to determine how genetic and environmental variation affects the immune system. Study visits consist of taking vitals and collecting biological fluids, such as blood. You will be compensated for participating in this study.
Condition: Healthy Volunteers
Investigator: Christine Kim Garcia, MD
Status: Currently Recruiting
The purpose of this study is to identify genetic causes of lung diseases and to develop a research repository so that we can better understand, prevent and treat these conditions. You have been asked to join this study as a healthy control. Even though you do not have lung disease, your sample is valuable to us. For example, you may be related to someone…