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Displaying 1 - 71 of 71
Condition: COVID-19 (Coronavirus)
Investigator: Andrew Einstein, MD
Status: Currently Recruiting
We are seeking patients that have had a pre-COVID heart CT scan (Coronary Computed Tomography Angiography) that was performed at Columbia University Irving Medical Center/NewYork-Presbyterian Hospital before March of 2020. For this study, half of patients will be required to have had COVID-19 symptoms (e.g., fever, cough, shortness of breath) and would have…
Condition: Psychiatric Disorders / Depression
Investigator: Sarah Herzog, PhD
Status: Currently Recruiting
We are conducting a study on depression and suicide risk, and participants can earn up to $300 for taking part. Suicide rates in the U.S. are rising, and new treatments are urgently needed. This study focuses on the brain chemical glutamate, which may play an important role in mood and mental health. We will compare glutamate levels at rest and during…
Condition: COVID-19 (Coronavirus)
Investigator: Melissa Stockwell, MD, MPH
Status: Currently Recruiting
Help us to better understand the long term effects of COVID. If you or your child has had COVID, or is feeling the long term effects of COVID, you might be able to help us understand more about it and treat it. Even if you or your child has never had COVID, you might be able to help. We are seeking volunteers who are under 25 to join the NIH RECOVER…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Currently Recruiting
We want to assess the baseline and cumulative seroprevalence of SARS-CoV-2 using serological and molecular assays. We will also administer a survey. Findings from this study will inform; 1) our understanding of changing epidemiology of COVID-19; 2) use of serological assays and testing algorithms, and 3) approaches to managing psychosocial stress in the…
Condition: Psychiatric Disorders / Depression
Investigator: Randy Auerbach, PhD
Status: Currently Recruiting
We are recruiting depressed adolescents ages 13-18 years. As a participant in our study, we will: (1) interview your child about current and past thoughts, feelings, and behaviors, (2) teach your child mindfulness strategies, (3) collect brain activity data with MRI (non-invasive) while your child practices mindfulness, and (4) send short surveys to your…
Condition: COVID-19 (Coronavirus)
Investigator: Deborah Theodore, MD
Status: Currently Recruiting
This is a study for people with symptoms of long COVID. We are looking for people over the age of 18 who are interested in participating in a study to understand whether a mindfulness meditation intervention can help improve symptoms of long COVID. Study participation lasts 6 months and is fully remote.
Condition: COVID-19 (Coronavirus)
Investigator: Michael Yin, MD
Status: Currently Recruiting
We are seeking volunteers who have been diagnosed with COVID-19 by a healthcare provider or by lab testing. We are also looking for volunteers who have never tested positive for COVID-19 and have not received a COVID-19 vaccine. The study, also known as C-PIC, will be looking at antibody levels and how long the virus remains in the body. We are also…
Condition: COVID-19 (Coronavirus)
Investigator: Bernard Chang, MD, PhD
Status: Currently Recruiting
The purpose of this study to examine the long-term general psychological symptoms, and identify the predictors of these psychological symptoms. The sustained psychological toll of working in a high-stress environment can have downstream impacts on health. It is therefore important to also consider how psychological factors influence physical health, for…
Condition: Psychiatric Disorders / Depression
Investigator: Marcella Walker, MD
Status: Currently Recruiting
Depression and some antidepressants may be associated with an increased risk of breaking a bone. It is not clear why this could be the case. It is possible that depression and/or certain medications used for the treatment of depression cause bone loss, increase the risk of falls, are associated with lower physical activity, or effects on muscle function.…
Condition: COVID-19 (Coronavirus)
Investigator: Jonathan Overdevest, MD, PhD
Status: Currently Recruiting
Our research team at Columbia University is trying to understand the impact of COVID-19 on smell and taste (chemosensory) dysfunction among adult patients from the Greater New York City area. Current areas of study include: 1) Investigation of smell and taste recovery patterns among patients with COVID-19; 2) Studies on how recovery of smell and taste after…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Currently Recruiting
We are looking for individuals over 18 years old who are interested in learning more about COVID-19 prevention research studies. We will ask you to complete a brief questionnaire to find out if you may be eligible for one of our studies. We can then schedule a phone call, teleconference, or in-person education visit so you can learn about the research we do…
Condition: Cancer / Brain Cancer
Investigator: Mikhail Doubrovin, MD
Status: Closed
The purpose of the study is to evaluate the safety of Lutathera alone in patients with recurrent glioblastoma and the combination of Lutathera with radiotherapy with temozolomide (TMZ) in patients with newly diagnosed glioblastoma (GB) and to establish the appropriate dose of this combination. Lutathera is a radioligand therapy, which is a targeted…
Condition: Psychiatric Disorders / Depression
Investigator: Joshua Berman, MD, PhD
Status: Closed
Are you suffering from chronic depression? We are seeking participants for a depression treatment research study at Columbia University using Transcranial Magnetic Stimulation (TMS). This study develops a more accurate TMS to treat chronic depression. Participation includes clinical assessments and magnetic resonance imaging (MRI). You will receive 27…
Condition: COVID-19 (Coronavirus)
Investigator: Michael Yin, MD
Status: Closed
A study looking at improving gut health and cognitive symptoms in Long COVID patients. A 4-week study taking a prebiotic (fiber) with a probiotic bacteria (Synbiotic). The study involves 2 in-person study visits which involves online surveys, cognitive testing, blood samples, stool samples, and rectal swab samples. Each completed study visit pays you $80 in…
Condition: COVID-19 (Coronavirus)
Investigator: Elizabeth Oelsner, MD, MPH
Status: Closed
This study is called the COVID-19 Lung Microvascular and Parenchymal Sequelae (LUNG MaPS) Study. The purpose of the study is to learn about the effects of COVID-19 infections on the lungs and heart, and to improve our understanding of why some COVID-19 patients experience ongoing symptoms, or what is often called "long COVID." Hundreds of…
Condition: Cancer / Brain Cancer
Investigator: Stergios Zacharoulis, MD
Status: Closed
Children and young adults with diffuse midline glioma will be treated with Focused Ultrasound (FUS) with DEFINITY microbubbles and neuro-navigator-controlled sonication. The overall goal of this study is to see if the study treatment plan will improve the outcome of participants with diffuse midline glioma, for which no known cure exists, and determine…
Condition: Cancer / Brain Cancer
Investigator: Mary Welch, MD
Status: Closed
The purpose of this study is to test good and bad effects of these two different drugs against meningioma tumors with altered genes. Today, therapy for meningioma is the same for all patients and is not based on tumor genetic testing. This trial is trying to see if tumor genetic testing would be helpful at guiding treatment in patients with meningioma.…
Condition: Cancer / Brain Cancer
Investigator: Gurcharanjeet Kaur, MD
Status: Closed
The purpose of this study is to find out if REC-2282, an investigational new drug, is an effective and safe treatment in patients with progressive NF2 mutated meningiomas who have either NF2 disease-related meningioma or recurrent sporadic meningiomas that have NF2 mutation. Investigational new drug means a drug that has not been approved as a marketed…
Condition: Cancer / Brain Cancer
Investigator: Fabio Iwamoto, MD
Status: Closed
The purpose of this study is to see how safe and effective Safusidenib erbumine, the study drug, is in treating brain glioma and to find the recommended dose of the study drug for clinical studies. Safusidenib is not Food and Drug Administration (FDA) approved.
Condition: COVID-19 (Coronavirus)
Investigator: Dani Dumitriu, MD, PhD
Status: Closed
This study aims to understand the impact of the COVID-19 pandemic on mother and infant health outcomes in pregnant women delivering at NewYork-Presbyterian Morgan Stanley Children's Hospital or Allen Pavilion Hospital. Data will be collected through online surveys, video visits, and electronic health records.
Condition: Cancer / Brain Cancer
Investigator: Andrew Lassman, MD
Status: Closed
The purpose of this study is to test the safety of a new vaccine, VBI-1901, and to know more about its ability to boost the response of the immune system against Cytomegalovirus. The reason for testing this vaccine in people with a brain tumor is that it might one day be used to boost the ability of the immune system to fight a certain type of brain tumor.…
Condition: COVID-19 (Coronavirus)
Investigator: Lenin Grajo, PhD
Status: Closed
We are seeking caregivers like you, caregiving for people who have had COVID-19 and are still experiencing symptoms, to participate in a research study titled A Caregiver Training Program to enhance COVID-19 Patient Readiness. The training program is designed to give you tools to reduce caregiver burden and stress levels. Caregivers must meet the following…
Condition: Cancer / Brain Cancer
Investigator: Mary Welch, MD
Status: Closed
The purpose of this study is to evaluate how safe the investigational drug, DSP-0390, is at different doses and to identify a recommended dose that is safe for further study. Investigational means that the study drug is currently being tested and has not been approved for use alone or in combination with any drug by the U.S. Food and Drug Administration (…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The main purpose of this study is to evaluate the ability of an experimental oral drug called S-217622 to improve the health of people with coronavirus disease 2019 (COVID-19). We also want to see if this study drug is safe, and if this study drug can shorten the time you have COVID-19 symptoms, reduce the amount of virus in the body, and prevent…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
Pfizer and Columbia University Irving Medical Center (CUIMC) are conducting a trial to learn about the safety and effectiveness of an experimental COVID-19 treatment, nirmatrelvir co-packaged with ritonavir, for children with COVID-19 that are at risk of the infection getting worse. Nirmatrelvir/ritonavir has been shown to be effective in fighting SARS-CoV-…
Condition: COVID-19 (Coronavirus)
Investigator: Melissa Stockwell, MD, MPH
Status: Closed
The purpose of this study is to assess the effectiveness of influenza and SARS-CoV-2 vaccines for preventing transmission of infections in households. We are seeking volunteers who have been recently diagnosed with COVID-19 or Influenza virus infection by either rapid diagnostic assay or RT-PCR in the last 7 days and live in a household with at least one…
Condition: Cancer / Brain Cancer
Investigator: James Hinkley Garvin Jr, MD
Status: Closed
The purpose of this study is to find the best dose of a drug called MTX110 and a contrast agent called gadolinium that can be given safely in children with newly diagnosed diffuse midline gliomas, which is a kind of brain tumor. All patients enrolled in the study will receive infusion of MTX110 and Gadolinium delivered with a pump directly into the tumor…
Condition: Psychiatric Disorders / Depression
Investigator: Randy Auerbach, PhD
Status: Closed
This study uses smartphone technology to better understand changes in adolescent moods over time. As a participant in our study, we would: (a) interview your child about current and past thoughts, feelings, and behaviors and (b) collect data from your child's smartphone for 6 months through an app called the Effortless Assessment of Risk States (EARS;…
Condition: COVID-19 (Coronavirus)
Investigator: Philip De Jager, PhD
Status: Closed
We need your help today to gather information about the experience of multiple sclerosis (MS) patients and the general population during the COVID-19 pandemic. Most MS patients take one of over a dozen of medications to control their disease, and these medications alter the immune system. These effects are not as strong as those experienced by patients with…
Condition: COVID-19 (Coronavirus)
Investigator: Marcus Pereira, MD, MPH
Status: Closed
The purpose of this study is to evaluate the safety, immune response, and efficacy of the Moderna mRNA-1273 SARS-CoV-2 vaccine in solid organ transplant recipients and healthy controls. Adult kidney and liver transplant recipients and healthy control participants who are at least 18 years of age will be enrolled. The current study aims to evaluate the…
Condition: Psychiatric Disorders / Depression
Investigator: Doron Amsalem, MD
Status: Closed
We are conducting research to explore self-stigma around depression, racial/ethnic and cultural experiences, and barriers to care (e.g., embarrassment, limited access, low expectations/motivation). Self-stigma refers to negative beliefs a person has about themself due to their mental illness. We are looking for Latinx or Black young adults ages 18-25 who…
Condition: Psychiatric Disorders / Depression
Investigator: Doron Amsalem, MD
Status: Closed
We are conducting research to explore the level of self-stigma around depression, racial/ethnic and cultural experiences, and barriers to care (e.g., embarrassment, limited access, low expectations/motivation). Self-stigma refers to negative beliefs a person has about themself due to their mental illness. We are looking for Latinx or Black young adults ages…
Condition: Psychiatric Disorders / Depression
Investigator: Doron Amsalem, MD
Status: Closed
We are conducting a research study to explore discrimination around depression and barriers to care in youth ages 14-18. We will use what we learn to create videos to reduce such discrimination. Parental permission is required for this study. Adolescents (ages 14-18) will participate in an individual interview that will be approximately 45 minutes long. We…
Condition: Cancer / Brain Cancer
Investigator: Andrew Lassman, MD
Status: Closed
The purpose of this research study is to see if the combination of medications approved for the treatment of glioblastoma, together with the study drug, selinexor (also known as XPOVIO), has any effects on your cancer. Selinexor works by trapping tumor suppressor proteins within the cell nucleus. This is expected to cause the cancer cells to die or stop…
Condition: Cancer / Brain Cancer
Investigator: Andrew Lassman, MD
Status: Closed
This study is being done to evaluate the safety and usefulness of the study drug, AG-881, as compared to placebo (a medically inactive substance) in residual or recurrent non-enhancing Grade 2 glioma (a type of brain cancer) that has a mutation in the IDH1 or IDH2 metabolic enzyme (a substance produced by the body to assist in breaking down chemicals).…
Condition: Cancer / Brain Cancer
Investigator: Andrew Lassman, MD
Status: Closed
The purpose of this research study is to test how safe and how well an investigational drug known as ONC201 works in treating high grade glioma (a type of brain cancer). The FDA (the U.S. Food and Drug Administration) has not approved ONC201 as a treatment for this condition.
Condition: Psychiatric Disorders / Depression
Investigator: Elizabeth Sublette, MD, PhD
Status: Closed
This research study uses non-invasive brain imaging called functional near-infrared spectroscopy (fNIRS). For fNIRS, a small infrared bulb shines light through the skull, and a special light detector is able to measure oxygen use in the brain. Our goal is to understand oxygen use by brain mitochondria cells in major depression and how this is affected by…
Condition: Psychiatric Disorders / Depression
Investigator: Jeffrey Miller, MD
Status: Closed
The goal of this study is to examine how effective and well-tolerated a possible new treatment for individuals who injure themselves frequently will be. All research procedures can be done from home no in-person visits are required. We are studying a minimal-risk form of electrical brain stimulation called transcranial direct current stimulation, or tDCS.…
Condition: Cancer / Brain Cancer
Investigator: Andrew Lassman, MD
Status: Closed
The purpose of this study is to measure how well and how safe eflornithine is in combination with lomustine, compared to lomustine taken alone, in treating patients whose anaplastic astrocytoma has come back after radiation and chemotherapy. Safety and how well you can tolerate the drug will be determined on the basis of physical exams, laboratory tests,…
Condition: Psychiatric Disorders / Depression
Investigator: David Hellerstein, MD
Status: Closed
We are currently enrolling individuals with Major Depressive Disorder (MDD) to participate in this research study. This is a one-year open-label study to evaluate the long-term safety and tolerability of an investigational drug called REL-1017 (esmethadone) when taken alone (monotherapy) or when taken with other antidepressants (adjunctive therapy). Study…
Condition: Psychiatric Disorders / Depression
Investigator: Jeffrey Miller, MD
Status: Closed
Do you suffer from depression? Have standard treatments not been helpful? Researchers at Columbia University Irving Medical Center are conducting a study of an experimental antidepressant called ketamine, which can provide rapid relief of depressive symptoms in some patients. The study involves an inpatient stay, during which participants undergo brain…
Condition: COVID-19 (Coronavirus)
Investigator: Ellen Morrison, MD, MPH
Status: Closed
This study enrolls people recently diagnosed with COVID-19, who are not currently in the hospital. The study tests several different investigational medicines to see if they are safe and can help adults with COVID-19 get better, with the goal of quickly determining those that are safe and effective. Help us to rise above COVID-19!
Condition: Psychiatric Disorders / Depression
Investigator: David Hellerstein, MD
Status: Closed
Patients who are either interested in discontinuing their current antidepressant or have discontinued an antidepressant in the past 6 weeks will be provided with an FDA approved medicine, Vortioxetine (brand name Trintellix). Treatment with Vortioxetine will start after the past antidepressant is discontinued. Vortioxetine dosage is adjustable throughout…
Condition: Psychiatric Disorders / Depression
Investigator: Patrick Brown, PhD
Status: Closed
The goal of this open-administration treatment study of escitalopram (or duloxetine) is to evaluate the effect of antidepressant medication on treating the syndrome of frailty in older adults with depressive symptoms. Patients with significant depressive symptoms and 1 or more symptoms of the frailty syndrome (exhaustion, decreased energy, weight loss,…
Condition: Psychiatric Disorders / Depression
Investigator: Yuval Neria, PhD
Status: Closed
Approximately half of the individuals with Post-traumatic Stress Disorder (PTSD) present with major depressive disorder (MDD). Compared to PTSD alone, patients with comorbid PTSD-MDD demonstrate greater distress and poorer treatment outcome. The goal of this pilot study is to collect preliminary data on the feasibility, safety, and initial efficacy of an…
Condition: COVID-19 (Coronavirus)
Investigator: Max O'Donnell, MD, MPH
Status: Closed
The purpose of this study is to test a medication to treat COVID-19 called remdesivir (RDV) that has not yet been approved by the FDA. If you choose to take part in this study, you will continue to receive the standard care for COVID-19. In addition, you will be randomized to either a 5-day or a 10-day treatment with RDV intravenously (by vein in the arm).…
Condition: Psychiatric Disorders / Depression
Investigator: Ian Kronish, MD
Status: Closed
This study will allow cancer survivors an opportunity to learn whether light therapy is helpful to them in addressing common concerns of cancer survivors such as fatigue, feeling low, and/or trouble sleeping by engaging in an N-of-1 or individualized trial.
Condition: COVID-19 (Coronavirus)
Investigator: Jennifer Woo Baidal, MD, MPH
Status: Closed
We are interested in studying the health of you and your family. Our study involves completing an online survey about your and your family's health and behaviors, and giving us access to basic health information that includes you and your child's vitals, weight/height, and BMI. You can receive up to $45 in Amazon pay cards for your participation.…
Condition: Psychiatric Disorders / Depression
Investigator: Franklin Schneier, MD
Status: Closed
If you are depressed and have not received course of medication treatment for depression in the past, you may be eligible for a study involving brain imaging and research treatment at no cost to you. The research treatment is with a medication that is not FDA-approved for depression. The study uses two types of brain imaging, position emission tomography (…
Condition: COVID-19 (Coronavirus)
Investigator: Yael Hirsch-Moverman, PhD
Status: Closed
We are conducting an NIH-funded study to understand how our bodies respond to and recover from the coronavirus and the COVID-19 disease that it causes. If you received a diagnosis of SARS-COV-2 infection and are recovering/or have recovered from COVID-19, you may be eligible to participate in one or more study visits. At each visit you will be asked to…
Condition: COVID-19 (Coronavirus)
Investigator: Eldad Hod, MD
Status: Closed
We are looking for volunteers who have recovered from COVID-19 to donate blood for treatment of others with this virus. Your plasma donation will help up to three people who are currently fighting this virus. Due to the high volume of inquiries, please send an inquiry through RecruitMe by clicking the "Do You Qualify" button. We're receiving…
Condition: COVID-19 (Coronavirus)
Investigator: Melissa Stockwell, MD, MPH
Status: Closed
The C-HEaRT Study: Families with Children Needed for Home-Based COVID-19 Study in Washington Heights/Inwood and Hamilton Heights, NYC. About the study: Weekly, at-home, self-collected nasal swabs (Fall 2020 through Spring 2021), Ship them directly in a prepaid container. Family notified if test positive for COVID-19. Three blood draws for adults (optional…
Condition: Psychiatric Disorders / Depression
Investigator: David Hellerstein, MD
Status: Closed
This is a pre-marketing (Phase 2A) multi-site study of an investigational drug, ganaxolone, as a potential treatment for non-psychotic post-partum depression. Eligible subjects who agree by signing informed consent will spend four days on the 5-South Research Unit (5-S) of the New York State Psychiatric Institute. For 6 hours they will have an tube in a…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The HIV Vaccine Trials Network (HVTN) and Columbia University Irving Medical Center are doing a study to learn more about SARS-CoV-2 infection and the COVID-19 disease that it can cause. The purpose of this study is to learn more about infection with and recovery from the virus called SARS-CoV-2. Some people know this virus by the name coronavirus. It can…
Condition: COVID-19 (Coronavirus)
Investigator: Jon Giles, MD
Status: Closed
If you currently live in the same household as someone who has tested positive for novel coronavirus (COVID-19), you might be eligible to participate in a trial that will test if a medicine used to prevent malaria, hydroxychloroquine, might reduce the risk of your developing COVID-19 symptoms. COVID-19 is a massive threat to public health worldwide. Post-…
Condition: COVID-19 (Coronavirus)
Investigator: Elisa Konofagou, PhD
Status: Closed
An ultrasound imaging study to assess the long terms effect of past COVID-19 infection in the heart, lung and vessels of recovered patients.
Condition: COVID-19 (Coronavirus)
Investigator: Anca Askanase, MD, MPH
Status: Closed
The purpose of this research study is to determine if chloroquine is effective in health care workers with moderate to high risk of exposure to COVID-19 in preventing symptomatic COVID-19 infections. The time frame for your involvement in the study is 3 months. During month 0, participants will be screened and randomized (like a flip of a coin) to a 3-month…
Condition: Psychiatric Disorders / Depression
Investigator: Ellie McGlinchey, PhD
Status: Closed
We are conducting research to compare different ways of improving sleep and mood in teens. Treatment involves Behavioral Sleep Therapy and Interpersonal Psychotherapy for Adolescents targeting: depression trouble falling and staying asleep not feeling rested on waking feeling sleepy during the day. Study Procedures: ~ A free, thorough diagnostic evaluation…
Condition: COVID-19 (Coronavirus)
Investigator: Deborah Theodore, MD
Status: Closed
The HERO program has two parts: the HERO Registry and the HERO-HCQ Trial. The HERO Registry is asking hundreds of thousands of U.S. healthcare professionals to join, including nurses, therapists, physicians, emergency responders, food service workers, environmental services workers, interpreters, and transporters anyone who works in a setting where people…
Condition: COVID-19 (Coronavirus)
Investigator: David Ho, MD
Status: Closed
Due to the high volume of inquiries, please inquire through RecruitMe. A study to isolate and determine the antibody response in patients who have recovered from COVID-19 for the development of monoclonal antibodies for prevention and treatment of coronavirus infections. We are doing this study to develop antibodies against coronavirus to prevent and treat…
Condition: COVID-19 (Coronavirus)
Investigator: Brian Fallon, MD
Status: Closed
Do you know anyone struggling with anxiety or worry related to any aspect of our current COVID-19 pandemic? This research study is an online low-intensity treatment study which aims to reduce anxiety and enhance resilience in this troubled time. All participants will receive brief anxiety reduction training using cognitive-behavioral strategies. In addition…
Condition: COVID-19 (Coronavirus)
Investigator: Max O'Donnell, MD, MPH
Status: Closed
There are no approved medications to treat COVID-19, a new disease caused by a virus called SARS-CoV-2 that was just identified in late 2019. Some people who become sick with COVID-19 develop a very serious disease. The purpose of this study is to see if Remdesivir (RDV) can improve your health from being sick with COVID-19 infection. The other purpose of…
Condition: Psychiatric Disorders / Depression
Investigator: Michael Grunebaum, MD
Status: Closed
If you're experiencing an acute psychiatric emergency, please stop negotiating this website and call 911 or go to the nearest emergency room. This website is not designed to address an acute psychiatric emergency. Purpose: To find out whether intranasal ketamine, when added to standard antidepressant treatment, improves the outcome of treatment for…
Condition: COVID-19 (Coronavirus)
Investigator: Max O'Donnell, MD, MPH
Status: Closed
If you want to be a plasma donor please go to (https://recruit.cumc.columbia.edu/clinical_trial/1929). The purpose of this research study is to find out whether antibodies collected from the blood of people, who have been infected with the virus SARS-CoV-2 and recovered from COVID-19, can be used to reduce the risk of severe disease or death in people with…
Condition: COVID-19 (Coronavirus)
Investigator: Ellen Morrison, MD, MPH
Status: Closed
We are conducting a CoVPN-funded study to understand if monoclonal antibodies can protect people exposed to SARS-COV-2 from developing the COVID-19 disease that it causes. If you live with someone recently diagnosed with COVID, you may be eligible to participate in one or more study visits. At each visit you will be asked to provide blood, nasal, and urine…
Condition: COVID-19 (Coronavirus)
Investigator: Christine Kim Garcia, MD
Status: Closed
Have you recovered from COVID-19 pneumonia? The FAR-ILD study is designed to detect and study the earliest stages of ILD in at-risk adults, including those who have had a severe viral pneumonia. FAR-ILD is a non-interventional study. This means that FAR-ILD is not involved in testing any new interventions or therapies. The purpose of FAR-ILD is to gather…
Condition: Psychiatric Disorders / Depression
Investigator: Joan Prudic, MD
Status: Closed
We are performing functional MRI (fMRI) scans before starting and after completing an acute course of electroconvulsive therapy (ECT) treatment. These scans are being performed to identify brain changes that occur after an acute course of ECT for participants with treatment-resistant depression. We also intend to perform two follow-up fMRI scans at two-…
Condition: Psychiatric Disorders / Depression
Investigator: Patrick Brown, PhD
Status: Closed
We are studying the relationship between mitochondrial function and the experience of fatigue. Mitochondria are the powerhouses of the cell. Cells within different organs contain hundreds to thousands of mitochondria, which sustain life and fuel energy-dependent processes that we do every day including muscle contraction and cognitive activity. They act…
Condition: Psychiatric Disorders / Depression
Investigator: Randy Auerbach, PhD
Status: Closed
We are seeking adolescents ages 13-17 to participate in a study on anhedonia. Anhedonia is the reduced ability to feel pleasure or enjoy things, and is a key feature of depression and other mental illnesses. If you believe your child is experiencing anhedonia, they may be eligible to participate in this study. If your child participates in this study, we…
Condition: COVID-19 (Coronavirus)
Investigator: Jessica Justman, MD
Status: Closed
The aim of the study is to assess the safety, efficacy, and immunogenicity of AZD1222 for the prevention of COVID-19. The COVID-19 pandemic has caused major disruption to healthcare systems with significant socioeconomic impacts. Currently, there are no specific treatments available against COVID-19 and accelerated vaccine development is urgently needed. A…
Condition: COVID-19 (Coronavirus)
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The main purpose of this study is to determine if sarilumab is safe and if it can decrease the amount of time a person has COVID-19 symptoms. Sarilumab (also known as Kevzara ) is considered an investigational drug in this study because it has not been approved for marketing by any health authority for the condition being studied but it has been approved in…