320 Studies Now Enrolling
Menu
Search
Medical Condition
- Show all (1940)
- Addiction (18)
- Allergy, Asthma, & Immunology (13)
- All of Us Research Program - NIH (1)
- Autoimmune Disorders (28)
- Blood Disorders (39)
- Bone & Muscle (10)
- Cancer (745)
- Child Development (4)
- COVID-19 (Coronavirus) (36)
- Critical Illness (1)
- Diabetes (21)
- Ear, Nose and Throat (11)
- Endocrine & Metabolic Disease (12)
- Eye (7)
- Gastrointestinal and Digestive Diseases (25)
- Hair and Skin Disorders (3)
- Headaches (5)
- (-) Healthy Volunteers (183)
- Heart Disease (128)
- Infectious Disease (49)
- Insomnia (2)
- Kidney Disease (12)
- Liver Disease (51)
- Lung Disease (31)
- Meniere's Disease (1)
- Neurological Disorders (178)
- Nutrition (7)
- Obesity (9)
- Obstetrics & Gynecology (53)
- Pain Management (1)
- Pediatrics (103)
- (-) Psychiatric Disorders (65)
- Rehabilitation (8)
- Stroke (6)
- Surgery (7)
- Transplant (53)
- Urology (4)
- Vascular Conditions (10)
Displaying 201 - 248 of 248
Condition: Healthy Volunteers
Investigator: Carmela Alcantara, PhD
Status: Closed
The Latino Sleep and Health Study (LASH) is a community study of Latino adults that is focused on understanding the relationship between sleep, stress, self-control, and health. Participation in LASH is fairly simple. If you are found eligible after taking the screener, you will be asked to complete an in-person survey. You can earn $20 for after completing…
Condition: Healthy Volunteers
Investigator: Thomas Nickolas, MD, MS
Status: Closed
The BoneGN study will help us learn how bones and muscles are responding to Glomerular Diseases. These conditions may gradually weaken bones and increase the risk of having a fracture (broken bone). In the future, the results can contribute in developing strategies to improve the bone health. We are looking for healthy children and adults between 5 and 55…
Condition: Healthy Volunteers
Investigator: Sharon Mannheimer, MD
Status: Closed
This is a COVID transmission study happening across the US to help us learn whether the COVID-19 vaccine stops the spread of the SARS-CoV-2 virus (COVID): both initial infection and transmission to others. The answer to this question can have an important impact on all of our lives. Currently we are enrolling unvaccinated people. You will not be required to…
Condition: Healthy Volunteers
Investigator: Yuval Neria, PhD
Status: Closed
Emerging research has demonstrated a relationship between visual attention patterns and anxiety disorders, including PTSD. This study is designed to examine these visual attention patterns using eye-tracking A simple device that monitors eye-movements. The study included two sessions conducted approximately 1 week apart, each no longer than 1 hour. In both…
Condition: Psychiatric Disorders / Anxiety
Investigator: Jonathan Posner, MD
Status: Closed
The goal of this study is to advance our understanding of how the brain processes emotion in adolescents. Adolescents with and without symptoms of anxiety are invited to participate. This study takes place over two days and includes an evaluation and a brain imaging session. Participants will be compensated up to $250. This study does not provide treatment.
Condition: Healthy Volunteers
Investigator: Helen Simpson, MD, PhD
Status: Closed
The purpose of this research study is to learn whether exercise affects learning and memory in people with anxiety. This is not a treatment study. The exercise program in this study runs for 6 weeks total. Each week, you are required to exercise 4 times for 12-15 minutes on the stepper machine that will be provided for you. You will be asked to visit our…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, MD
Status: Closed
Almost 40,000 people get HIV in the U.S. each year and almost all occur via sexual contact, especially male-to-male contact. The number of new infections has decreased slightly each year, however, we need other HIV prevention tools, such as developing a greatly, effective HIV vaccine, to better reduce HIV infections. SCREENING AND EDUCATION: 1. Consent will…
Condition: Psychiatric Disorders / Obsessive Compulsive Disorder (OCD)
Investigator: Helen Simpson, MD, PhD
Status: Closed
The purpose of this pilot research study is to test whether certain components of the marijuana plant, known as "cannabinoids", may help to reduce symptoms in patients with OCD. Specifically, patients enrolled in the study will smoke marijuana containing different concentrations of 2 different cannabinoids, THC and CBD. Both of these agents act on…
Condition: Healthy Volunteers
Investigator: Melanie Gold, MD
Status: Closed
Auriculotherapy is a type of Eastern medicine that has been used for thousands of years involving the ear. The ear has nerve connections to the whole body, and therefore using non-invasive techniques can be used to treat a wide variety of problems. This study is looking to see if auriculotherapy might be used to treat abdominal pain and find areas on the…
Condition: Psychiatric Disorders / ADD/ADHD
Investigator: Jonathan Posner, MD
Status: Closed
Children with Attention-Deficit/Hyperactivity Disorder (ADHD) are typically treated with two types of medications: stimulants and non-stimulants. These medications work in different ways to treat ADHD symptoms, but we do not fully understand the brain mechanisms underlying the medications' effects. This study will use MRI scanning to look at changes in…
Condition: Psychiatric Disorders / Anxiety
Investigator: Franklin Schneier, MD
Status: Closed
RESEARCH STUDY:Brief Intervention for Public Speaking Fears (IRB#7293).- Are you between the ages of 18 - 60?- Do you have bothersome fears of public speaking?- Are you interested in trying a novel intervention?This research study tests whether a brief intervention using a medication called propranolol is effective at reducing public speaking fears. This…
Condition: Healthy Volunteers
Investigator: Martha Welch, MD
Status: Closed
The purpose of this current study is to investigate the efficacy of a group model of Family NurtureIntervention in ameliorating behavioral problems in preschool-aged children. The behavioral, neurobiological and clinical insights gained from this project may eventually lead to better treatment of emotional, behavioral and developmental disorders. The…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Closed
We are doing this research study to find out how different amounts of sleep restriction affect yourbody's ability to generate heat. This study will determine the effects of partial sleep restriction (PSR) (4 h in bed) and total sleep deprivation (TSD) (0 h in bed) compared to a full night of habitual sleep (HS)(8 h in bed) on brown adipiose tissue (…
Condition: Psychiatric Disorders / Obsessive Compulsive Disorder (OCD)
Investigator: Helen Simpson, MD, PhD
Status: Closed
Eligible participants will be asked questions about their symptoms, complete questionnaires, and receive sessions of Cognitive-Behavioral therapy consisting of Exposure and Ritual Prevention (EX/RP) accompanied by the use of a mobile app. The purpose of this study is to assess whether the mobile app may be effective in improving symptoms of OCD.
Condition: Healthy Volunteers
Investigator: Nim Tottenham, PhD
Status: Closed
Parents! Join our research study! For families with 2-4 years olds, Complete from the comfort of your own home! Involves: Complete questionnaires; Collect a stool sample from your child; Provided with an easy to use kit and video instructions; Earn $25 for participating.
Condition: Healthy Volunteers / Exercise
Investigator: Richard Sloan, PhD
Status: Closed
This study focuses on the effects of aerobic conditioning on cognition and brain activity. Eligible participants will complete an exercise stress test, MRI, and cognitive testing session at the beginning and end of the study. Once participants complete the first set of appointments, they will be randomly assigned to one of two conditions for 12-weeks.…
Condition: Healthy Volunteers
Investigator: Yaakov Stern, PhD
Status: Closed
Train the Brain Study: The purpose of this study is to investigate the effect of a web-based (remote, at home) computerized cognitive training protocol on cognitive performance in healthy older adults. Thetraining will involve a daily life situation in a multi-task context. If you are eligible, you will be asked tocomplete 13 web-based sessions, twice a…
Condition: Healthy Volunteers
Investigator: Keith Diaz, PhD
Status: Closed
The phrase sitting is the new smoking has been coined due to an increase of excessive sitting in middle- and older-aged adults. However, there are currently no specific guidelines for the best way to break up long periods of sitting. This study will look at the effect of breaking up sitting periods with movement breaks on blood sugar levels. We are looking…
Condition: Psychiatric Disorders / Bipolar Disorder
Investigator: Martin Lan, MD
Status: Closed
We are trying to understand what causes bipolar disorder and how medications treat bipolar depression. If you participate, you will have two different brain scans (MRI and PET scan). You will also have antidepressant treatment for free. We will then be able to see whether information on the brain scans connects with how people do on the medications. The…
Condition: Psychiatric Disorders / Bipolar Disorder
Investigator: David Hellerstein, MD
Status: Closed
This study is a double-blind and placebo-controlled study to assess its efficacy of the new drug Lumateperone for patients with Major Depressive Episodes associated with Bipolar I and Bipolar II disorder. Lumateperone is thought to exert its antidepressant effect through interaction with sereotogenic, dopaminergic, and glutamergic neurotransmitter targets.…
Condition: Healthy Volunteers
Investigator: Micaela Martinez, PhD
Status: Closed
How does the light we experience in day-to-day life affect our body clock? Interested in joining a new project to help scientists at Columbia University understand how light pollution and light-at-night affects our body clock? You or your child may be eligible to participate. The study involves wearing a small light sensor on a lanyard and a temperature…
Condition: Healthy Volunteers
Investigator: Richard Sloan, PhD
Status: Closed
The purpose of this study is to examine the effect of dietary flavanols on brain activity and memory. Flavanols represent a specific group of plant derived nutrients that are found in cocoa beans, grapes, tea, berries and various other fruits and vegetables. The specific flavanols investigated in this study come from cocoa. Participants will be asked to…
Condition: Healthy Volunteers
Investigator: Cassia Wells, MD
Status: Closed
Antibodies are one of the natural ways that our bodies fight or prevent infection. We're testing an antibody to find out if it's safe, if they don't make people feel uncomfortable, how these study antibodies move throughout the body, and to measure antiviral activity. You cannot get HIV from the study antibody. First, request to be contacted…
Condition: Psychiatric Disorders / Depression
Investigator: David Hellerstein, MD
Status: Closed
Patients who are either interested in discontinuing their current antidepressant or have discontinued an antidepressant in the past 6 weeks will be provided with an FDA approved medicine, Vortioxetine (brand name Trintellix). Treatment with Vortioxetine will start after the past antidepressant is discontinued. Vortioxetine dosage is adjustable throughout…
Condition: Healthy Volunteers
Investigator: Marc Richmond, MD
Status: Closed
Patients with hypoplastic left heart syndrome and other single right ventricle lesions who have undergone the Fontan procedure have a high risk of neurodevelopmental disorders that affect quality of life and adulthood employment. This study will leverage the ongoing National Heart, Lung, and Blood Institute (NHLBI)-funded Single Ventricle Reconstruction…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, MD
Status: Closed
Antibodies are one of the natural ways that our bodies fight or prevent infection. Were testing an antibody to find out if its safe, if it doesn't make people feel uncomfortable and to find out what may be the best dose if its given by IV infusion or sub-cutaneous injection. You cannot get HIV from the Bispecific Antibody. We'll ask you to…
Condition: Healthy Volunteers
Investigator: Jeffrey Shaman, PhD
Status: Closed
You are invited to participate in a study that seeks to understand how respiratory virus infections affect human hosts at various stages of symptomology and predict future wellness states using biophysical measurements from a smartwatch. The goals are to identify biomarkers predictive of symptom outcome and develop early wellness prediction models. The…
Condition: Psychiatric Disorders / Bipolar Disorder
Investigator: Martin Lan, MD
Status: Closed
We are trying to understand what causes bipolar disorder and how medications treat bipolar depression. Particularly, we are looking at the importance of dopamine signaling in the process. If you participate, you will have two different brain scans (MRI and PET scan). You will also have treatment for your depression with an FDA approved medication,…
Condition: Psychiatric Disorders
Investigator: Ari Shechter, PhD
Status: Closed
We are currently looking for men and women, age 18-65 y, to participate in a sleep study. To participate you must have experienced insomnia (difficulty falling asleep, staying asleep, or experiencing sleep that is unrefreshing) for at least 1 month. This is a 2-phase outpatient and inpatient study. We will test 2 different non-drug based methods to improve…
Condition: Healthy Volunteers
Investigator: Allison Borowski, MD
Status: Closed
We are currently recruiting women to TMIST, a clinical trial that will help us develop strategies that tailor breast cancer screening to the risks of individual women. This is a screening trial. The purpose of this trial is to determine if tomosynthesis (3-D) mammography detects breast cancer at earlier stage than current method of 2-D digital mammography.
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Closed
The overall goal of this project is to determine whether short sleep duration is a risk factor for cardiovascular disease in women. We are currently looking for healthy, non-smoking women to participate in a sleep study. You must be willing to come to Columbia University Medical Center once a week for two 6-week periods and regularly sleep at least 7-9…
Condition: Psychiatric Disorders / Depression
Investigator: David Hellerstein, MD
Status: Closed
This is a pre-marketing (Phase 2A) multi-site study of an investigational drug, ganaxolone, as a potential treatment for non-psychotic post-partum depression. Eligible subjects who agree by signing informed consent will spend four days on the 5-South Research Unit (5-S) of the New York State Psychiatric Institute. For 6 hours they will have an tube in a…
Condition: Healthy Volunteers
Investigator: Helen Simpson, MD, PhD
Status: Closed
Obssesive Compulsive Disorder (OCD) and related disorders characterized by repetitive thoughts and behaviors (e.g., Tourette Syndrome and Eating Disorders) are severe conditions that lead to significant health-related disability. Dysfunction in the brain circuits involved in cognitive control and reward processing are thought to contribute to the symptoms…
Condition: Healthy Volunteers / Exercise
Investigator: Richard Sloan, PhD
Status: Closed
This study focuses on the effects of aerobic conditioning on cardiovascular function and inflammatory response. Eligible participants will complete an exercise stress test, laboratory visit, and cognitive testing session at three specific time points over the course of the study. Once the initial set of appointments is complete, participants are randomly…
Condition: Healthy Volunteers
Investigator: Moise Desvarieux, MD, PhD
Status: Closed
We are looking for people ages 65 and older to help us evaluate if an investigational drug improves muscle function, which can reduce risk of falls and fractures. To be considered for the study, you: 1. Must complete a pre-screening phone interview to assess your eligibility 2. If you are eligible, you will be invited to attend an in-person appointment at…
Condition: Psychiatric Disorders / Depression
Investigator: Patrick Brown, PhD
Status: Closed
We are studying the relationship between mitochondrial function and the experience of fatigue. Mitochondria are the powerhouses of the cell. Cells within different organs contain hundreds to thousands of mitochondria, which sustain life and fuel energy-dependent processes that we do every day including muscle contraction and cognitive activity. They act…
Condition: Healthy Volunteers
Investigator: Jeffrey Miller, MD
Status: Closed
The purpose of this study is to use Positron Emission Tomography (PET) to identify changes in brain chemistry that may cause an episode of depression. This study will be carried out in approximately 30 subjects. PET is a technique that provides "pictures" of chemical connections in the brain by injecting and monitoring a radioactive substance. In…
Condition: Psychiatric Disorders
Investigator: Yuval Neria, PhD
Status: Closed
Columbia University Medical Center is presently recruiting individuals who have experienced trauma to participate in an fMRI research study. For your participation, you will receive up to $270 and an opportunity to advance research in the area of trauma and PTSD. This study involves two visits.
Condition: Healthy Volunteers
Investigator: William Whang
Status: Closed
The purpose of this study is to evaluate the performance of a remote patient monitoring device against more established wired monitoring devices during common activities and low to moderate exercise.The goal of this study is to determine how the Zephyr BioPatch will work compared to more established wired monitoring devices. This study involves one visit,…
Condition: Psychiatric Disorders / Anxiety
Investigator: Franklin Schneier, MD
Status: Closed
We are currently enrolling individuals with social anxiety disorder to participate in this study. The purpose of this study is to assess whether a brief computer-based research treatment helps improve social anxiety symptoms. For eligible participants, this study will involve a brief, novel research treatment for social anxiety, delivered in 8 or 12…
Condition: Healthy Volunteers
Investigator: Richard Sloan, PhD
Status: Closed
The purpose of this research study is to determine whether ambulatory monitoring of blood pressure measured by a finger touch blood pressure monitor is a viable approach to measuring blood pressure in the field. A secondary aim is to determine whether the finger touch blood pressure monitor is influenced by individual differences in current stress levels…
Condition: Healthy Volunteers
Investigator: Sharon Oberfield, MD
Status: Closed
We are recruiting boys between 3-9 years old and girls between 3-8 years old to participate in a research study. Children who would like to participate must be healthy and not showing signs of puberty. The goal of the study is to understand the relationship between early body development, metabolism (sugars and fats processing), and the saliva microbiome (…
Condition: Psychiatric Disorders / Obsessive Compulsive Disorder (OCD)
Investigator: Reilly Kayser, MD
Status: Closed
The Center for OCD and Related Disorders at New York State Psychiatric Institute/Columbia University Medical Center is seeking individuals aged 18+ with obsessive-compulsive disorder (OCD) to participate in a survey regarding their experiences with marijuana/cannabis. We hope this study will lead to increased understanding of how these substances affect…
Condition: Psychiatric Disorders / Obsessive Compulsive Disorder (OCD)
Investigator: Helen Simpson, MD, PhD
Status: Closed
This study is investigating how the brains of people with OCD may change with treatment. The study uses Magnetic Resonance Imaging (MRI) to scan the brain, and the treatment used is a form of Cognitive-Behavioral therapy consisting of Exposure and Ritual Prevention (EX/RP). Participants will undergo a scan, which lasts for approximately 2 hours and takes…
Condition: Healthy Volunteers
Investigator: Brooke Aggarwal, EdD, MS, FAHA
Status: Closed
This study is active but is no longer enrolling new subjects.
Condition: Psychiatric Disorders / Depression
Investigator: Ellie McGlinchey, PhD
Status: Closed
We are conducting research to compare different ways of improving sleep and mood in teens. Treatment involves Behavioral Sleep Therapy and Interpersonal Psychotherapy for Adolescents targeting: depression trouble falling and staying asleep not feeling rested on waking feeling sleepy during the day. Study Procedures: ~ A free, thorough diagnostic evaluation…
Condition: Healthy Volunteers
Investigator: Suzanne Lewis, MD
Status: Closed
While optical colonoscopy (OC) is considered the gold standard for colorectal cancer screening, there are alternative approaches to visualization of the colon. Participants will receive screening by either colon capsule endoscopy (CCE) and computed tomographic colonography (CTC). They will be instructed to follow a detailed colon preparation regimen prior…
Condition: Healthy Volunteers
Investigator: Jonathan Posner, MD
Status: Closed
Children with Attention-Deficit/Hyperactivity Disorder (ADHD) are typically treated with two types of medications: stimulants and non-stimulants. These medications work in different ways to treat ADHD symptoms, but we do not fully understand the brain mechanisms underlying the medications' effects. This study will use MRI scanning to look at changes in…
This website uses cookies as well as similar tools and technologies to understand visitors’ experiences. By continuing to use this website,
you consent to Columbia University’s usage of cookies and similar technologies, in accordance with the
Columbia University Website Cookie Notice.
I AGREE