227 Studies Now Enrolling
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Displaying 201 - 255 of 255
Condition: Healthy Volunteers
Investigator: Kimberly Morel, MD
Status: Closed
This clinical study is being conducted for research purposes. The study cream, SD-101 (Zorblisa), has allantoin as the active ingredient and is being investigated for the treatment of the skin lesions which occur in patients with Epidermolysis Bullosa. The purpose of this clinical study is to study the effectiveness and safety of SD-101 (Zorblisa) in…
Condition: Healthy Volunteers
Investigator: Richard Sloan, PhD
Status: Closed
The purpose of this research study is to determine whether ambulatory monitoring of blood pressure measured by a finger touch blood pressure monitor is a viable approach to measuring blood pressure in the field. A secondary aim is to determine whether the finger touch blood pressure monitor is influenced by individual differences in current stress levels…
Condition: Psychiatric Disorders / Schizophrenia
Investigator: Jeffrey Lieberman, MD
Status: Closed
This study plans to learn more about an investigational new drug called lumateperone tosylate (ITI-007) and may help us find new types of treatment for schizophrenia and schizoaffective disorder.
Condition: Psychiatric Disorders / Obsessive Compulsive Disorder (OCD)
Investigator: Pablo Goldberg, M.D.
Status: Closed
The purpose of this study is to assess the effects of a single infusion of ketamine for adolescents and young adults with obsessive-compulsive disorder (OCD). Ketamine is a FDA-approved anesthetic medication that can possibly cause a rapid decrease in OCD symptoms. To be eligible to participate, patients need to have already tried at least one SRI…
Condition: Psychiatric Disorders / Bipolar Disorder
Investigator: Joshua Kantrowitz, Md
Status: Closed
We will evaluate the D-cycloserine (DCS) and lurasidone with MRI measurement of brain responses to DCS. DCS is a drug that works on the same brain receptor as ketamine. DCS is not approved by the FDA for bipolar depression. Study participants will receive a dose of lurasidone or placebo in one MRI and a dose of DCS in another, followed by an optional follow…
Condition: Healthy Volunteers
Investigator: Paula Castano, MD, MPH
Status: Closed
Columbia University is conducting a contraceptive clinical trial looking at two intrauterine devices, one of which is investigational. Pre-menopausal women ages 16-40 who are generally healthy, sexually active, at risk for pregnancy, and are not at risk for sexually transmitted infections may qualify.
Condition: Healthy Volunteers
Investigator: Eldad Hod, MD
Status: Closed
This study is for healthy volunteers. Volunteers who agree to be part of this research will be requested to donate up to 4 tube(s) of blood (approximately 4 teaspoons). The blood will be tested for 5 standard clotting assays. Volunteers will be asked to fill out a questionnaire as well. Compensation for completion of this study is $20.
Condition: Psychiatric Disorders / Depression
Investigator: Ian Kronish, MD
Status: Closed
This study will allow cancer survivors an opportunity to learn whether light therapy is helpful to them in addressing common concerns of cancer survivors such as fatigue, feeling low, and/or trouble sleeping by engaging in an N-of-1 or individualized trial.
Condition: Healthy Volunteers
Investigator: Julia Wynn
Status: Closed
This study is evaluating genomic screening in Ashkenazi Jewish and Hispanic communities. Genomic screening is done by collecting a blood sample and looking at a person's genes to learn if they are at high risk for certain health problems like cancer or heart disease or are at risk to have a child with a genetic condition. The study is designed to…
Condition: Healthy Volunteers
Investigator: Loren Gianini, PhD
Status: Closed
The goal of this study is to better understand why some people have managed to lose weight and keep it off while others have not. We are recruiting people who have lost weight and kept it off as well as healthy non-dieters with overweight or obesity who are not trying to lose weight. Study participation involves computer tasks, brain imaging, and eating a…
Condition: Psychiatric Disorders / Depression
Investigator: Yuval Neria, PhD
Status: Closed
Approximately half of the individuals with Post-traumatic Stress Disorder (PTSD) present with major depressive disorder (MDD). Compared to PTSD alone, patients with comorbid PTSD-MDD demonstrate greater distress and poorer treatment outcome. The goal of this pilot study is to collect preliminary data on the feasibility, safety, and initial efficacy of an…
Condition: Healthy Volunteers
Investigator: Eldad Hod, MD
Status: Closed
One of the consequences of donating blood is iron deficiency. In this study, we will screen healthy frequent blood donors for iron deficiency. We will enroll iron deficient donors and randomize them to intravenous iron treatment or placebo in order to determine whether iron deficiency has any harmful effects on the blood supply and the donors themselves.
Condition: Healthy Volunteers
Investigator: Blandine Laferrere, MD, PhD
Status: Closed
This pilot study is designed to examine the effect of a novel type of lifestyle intervention, administered via a smartphone app, on weight loss and improvement of metabolic health in individuals with overweight and/or obesity. A mobile application will be used to document eating behavior through photos. In addition, participants will receive personalized…
Condition: Psychiatric Disorders / Depression
Investigator: Michael Grunebaum, MD
Status: Closed
If you're experiencing an acute psychiatric emergency, please stop negotiating this website and call 911 or go to the nearest emergency room. This website is not designed to address an acute psychiatric emergency. Purpose: To find out whether intranasal ketamine, when added to standard antidepressant treatment, improves the outcome of treatment for…
Condition: Healthy Volunteers
Investigator: Yuval Neria, PhD
Status: Closed
Columbia University Medical Center is presently recruiting healthy individuals to participate in an fMRI research study. For your participation, you will receive up to $270 and an opportunity to advance research in the area of trauma and PTSD. This study involves two visits.
Condition: Healthy Volunteers
Investigator: Julie Franks, PhD
Status: Closed
Almost 40,000 people get HIV in the U.S. each year and almost all infections occur via sexual contact, especially male-to-male contact. The number of new infections has decreased slightly each year; however, we need other HIV prevention tools, including an effective HIV vaccine, to better protect people from HIV infection. An HIV vaccine is the best long-…
Condition: Psychiatric Disorders / Schizophrenia
Investigator: Joshua Kantrowitz, Md
Status: Closed
The purpose of this study is to determine whether the brain wave patterns are improved after administration of CVN058 compared to placebo in subjects with schizophrenia. The study uses electroencephalography (EEG) to measure naturally occurring brain waves as you listen to recorded sounds.
Condition: Psychiatric Disorders / Depression
Investigator: Patrick Brown, PhD
Status: Closed
The goal of this open-administration treatment study of escitalopram (or duloxetine) is to evaluate the effect of antidepressant medication on treating the syndrome of frailty in older adults with depressive symptoms. Patients with significant depressive symptoms and 1 or more symptoms of the frailty syndrome (exhaustion, decreased energy, weight loss,…
Condition: Healthy Volunteers
Investigator: Sharon Wardlaw, MD
Status: Closed
This 2-phase study aims to explore ways to predict who will respond well to the FDA approved weight loss drug lorcaserin and to understand the mechanisms that develop which limit drug efficacy. Subjects will be recruited for a 5-week crossover study (phase 1) with lorcaserin and placebo followed by treatment with lorcaserin for 24 weeks (phase 2). Phase 1…
Condition: Healthy Volunteers
Investigator: Rebecca Schnall, PhD, RN
Status: Closed
Take the Online Men's Health Survey (OMHS) today! Human Immunodeficiency Virus (HIV) and syphilis disproportionately affect men who have sex with men (MSM); however, this phenomenon is not well understood and is understudied in the United States. The OMHS study is being performed to help improve STI prevention and treatment services in the United…
Condition: Healthy Volunteers
Investigator: Micaela Martinez, PhD
Status: Closed
This study involves wearing a small light sensor on a lanyard and a temperature sensor in a wristband for one week in the summer, fall, winter and spring. The study will span 9 months. Participants will also be asked to fill out a daily questionnaire during those weeks. $30/week compensation or $120 in total for participation.
Condition: Healthy Volunteers
Investigator: Elizabeth Shane, MD
Status: Closed
Osteoporotic fractures affect the lives of 1.5 million Americans each year. Imaging tests, such as bone density, are used to predict fracture risk and to help guide therapy for fracture prevention. In this study we are validating a high-resolution, three-dimensional scanner with the overall goal of improving the diagnosis of bone diseases.
Condition: Psychiatric Disorders / Schizophrenia
Investigator: Guillermo Horga, MD, PhD
Status: Closed
In this study, we are trying to learn more about the symptoms of schizophrenia, specifically to learn how abnormalities in the brain may produce certain experiences that are common in patients with schizophrenia. The study involves clinical interviews, clinical chart review, computer tests, and magnetic resonance imaging (MRI) scans.
Condition: Healthy Volunteers
Investigator: Adam Brickman, PhD
Status: Closed
This study is associated with the Alzheimer's Disease Research Center (ADRC) at Columbia University. The study seeks to understand changes in the way the brain's structure and function are related to age, and the risk of developing memory problems, Alzheimer's disease (AD), and dementia. The study will use magnetic resonance imaging (MRI) to…
Condition: Healthy Volunteers
Investigator: Sumit Mohan, MD
Status: Closed
We are seeking your opinions regarding different organ donation policies, via a 5-10 minute survey; responses are all anonymous. Everyone who completes the survey will have the option to enter a draw for a $5 gift card.
Condition: Psychiatric Disorders / PTSD
Investigator: Yuval Neria, PhD
Status: Closed
Approximately half of the individuals with Post-traumatic Stress Disorder (PTSD) present with major depressive disorder (MDD). Compared to PTSD alone, patients with comorbid PTSD-MDD demonstrate greater distress and poorer treatment outcome. The goal of this pilot study is to collect preliminary data on the feasibility, safety, and initial efficacy of an…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, MD
Status: Closed
We are looking for healthy, HIV-negative individuals 18 to 50 years old who are interested in our studies that test antibodies for HIV prevention. Antibodies are one of the natural ways that our bodies fight or prevent infection. We are testing an antibody called VRC07-523LS against HIV. We will ask you to complete a brief questionnaire to find out if you…
Condition: Healthy Volunteers
Investigator: Stephen Arpadi, MD, MS
Status: Closed
We are seeking healthy volunteers (HIV-negative) for a study seeing if HIV is associated with faster biological aging among older African American adults, whether faster biological age is related to health conditions that typically occur in older people and whether these conditions might be due to stress or over-activity of certain parts of the immune…
Condition: Psychiatric Disorders / Depression
Investigator: Joan Prudic, MD
Status: Closed
We are performing functional MRI (fMRI) scans before starting and after completing an acute course of electroconvulsive therapy (ECT) treatment. These scans are being performed to identify brain changes that occur after an acute course of ECT for participants with treatment-resistant depression. We also intend to perform two follow-up fMRI scans at two-…
Condition: Healthy Volunteers
Investigator: Erika Berman-Rosenzweig, MD
Status: Closed
This research study is being conducted to study pulmonary hypertension and right heart dysfunction based on clinical, imaging, physiological and pathological characteristics. We hope to develop a new classification system and new methods to diagnose and treat pulmonary hypertension. Diagnostic testing includes (listed subsequently): full medical work-up,…
Condition: Healthy Volunteers
Investigator: Billy Caceres, PhD, RN
Status: Closed
This goal of this study is to learn more about how stress and coping might be associated with blood pressure in lesbian, gay, and bisexual adults. If you are deemed eligible, first you will be scheduled for a telephone or video conference interview with a member from the study team, which may take up to 1.5 hours. For the interview, you may be asked to…
Condition: Psychiatric Disorders / Schizophrenia
Investigator: Joshua Kantrowitz, Md
Status: Closed
The purpose of this study is to evaluate the efficacy, safety and tolerability of different doses and durations of TV-46000 given by subcutaneous (under the skin) injection as compared to placebo for use as a potential maintenance in adults with schizophrenia.
Condition: Psychiatric Disorders / Anxiety
Investigator: Franklin Schneier, MD
Status: Closed
RESEARCH STUDY:Brief Intervention for Public Speaking Fears (IRB#7293).- Are you between the ages of 18 - 60?- Do you have bothersome fears of public speaking?- Are you interested in trying a novel intervention?This research study tests whether a brief intervention using a medication called propranolol is effective at reducing public speaking fears. This…
Condition: Healthy Volunteers
Investigator: Franklin Schneier, MD
Status: Closed
We are currently enrolling healthy individuals to participate in a research study involving electroencephalography (EEG) and magnetic resonance imaging (MRI). Participants will complete 3 visits over the course of 2 weeks and receive up to $400 for their participation. The visits will involve a psychiatric assessment and medical history, playing computer…
Condition: Healthy Volunteers
Investigator: Kevin Ochsner, PhD
Status: Closed
The Social Cognitive and Affective Neuroscience (SCAN) Lab is currently running research studies to investigate social interactions. Our beliefs about those who are close to us are based on our previous interactions with them. This experiment examines exactly how interactions with close others lead to changes in our beliefs about their personality and our…
Condition: Healthy Volunteers
Investigator: Helen Simpson, MD, PhD
Status: Closed
The purpose of this research study is to learn whether exercise affects learning and memory in people with anxiety. This is not a treatment study. The exercise program in this study runs for 6 weeks total. Each week, you are required to exercise 4 times for 12-15 minutes on the stepper machine that will be provided for you. You will be asked to visit our…
Condition: Healthy Volunteers
Investigator: Marla Hamberger, PhD
Status: Closed
Some medical conditions in children involve difficulty with speech and language. Therefore, accurate measurement of these difficulties is important for both diagnosis and treatment. Unfortunately, the test that is currently used to assess object naming-- one of the most common language problems found in these conditions is the same test that is used for…
Condition: Psychiatric Disorders / Obsessive Compulsive Disorder (OCD)
Investigator: Yagna Pathak, PhD
Status: Closed
The study aims to assess the impact of repetitive transcranial magnetic stimulation (rTMS) on brain imaging and neurophysiological measures in patients with Obsessive-Compulsive Disorder (OCD).
Condition: Healthy Volunteers
Investigator: Christine Kim Garcia, MD
Status: Closed
The FAR-ILD study is designed to detect and study the earliest stages of ILD in adults with a family history of ILD. FAR-ILD is a non-interventional study. This means that FAR-ILD is not involved in testing any new interventions or therapies. The purpose of FAR-ILD is to gather data on family members of patients with pulmonary fibrosis over a long period of…
Condition: Healthy Volunteers
Investigator: Karen Bell, MD
Status: Closed
The purpose of this study is to test whether an investigational drug called solanezumab can slow the progression of memory problems associated with brain amyloid. The study will also test 1) whether the anti-amyloid treatment can slow evidence of AD-related brain injury on imaging tests to look at brain structure and function and 2) the effect of…
Condition: Psychiatric Disorders / PTSD
Investigator: Yuval Neria, PhD
Status: Closed
Emerging research has demonstrated a relationship between visual attention patterns and anxiety disorders, including PTSD. This study is designed to examine these visual attention patterns using eye-tracking A simple device that monitors eye-movements. The study included two sessions conducted approximately 1 week apart, each no longer than 1 hour. In both…
Condition: Healthy Volunteers
Investigator: Joyce Yu, MD
Status: Closed
The population includes males and females of all ages with one or more food allergy or those who are at risk of mortality from food-induced anaphylaxis. The FARE Patient Registry is a multicenter, prospective, longitudinal, observational cohort study of patients with food allergy. The participant and the treating physician agree that he/she will complete…
Condition: Healthy Volunteers
Investigator: Yael Cycowicz, Ph.D.
Status: Closed
This study investigates changes in brain responses to visual images presented both frequently and infrequently. 60 adults will be recruited for the study which will take place in a laboratory at the New York State Psychiatric Institute. You will see the visual images on a computer screen and will have to respond with a button press to only one image while…
Condition: Psychiatric Disorders
Investigator: James Whitworth, PhD
Status: Closed
The purpose of this study is to examine the physical and mental effects of exercise in adults who have experienced a recent traumatic event. Participation in this study requires attending 12 sessions at Teachers College Columbia University over the course of six weeks. Each session will last between 30 and 60 minutes. Participants will be compensated with…
Condition: Healthy Volunteers
Investigator: Nim Tottenham, PhD
Status: Closed
Parents! Join our research study! For families with 2-4 years olds, Complete from the comfort of your own home! Involves: Complete questionnaires; Collect a stool sample from your child; Provided with an easy to use kit and video instructions; Earn $25 for participating.
Condition: Healthy Volunteers
Investigator: Loren Gianini, PhD
Status: Closed
The goal of this study is to better understand why some people have managed to lose weight and keep it off while others have not. We are recruiting people who have lost weight and kept it off as well as healthy non-dieters with overweight or obesity who are not trying to lose weight. Study participation involves computer tasks, brain imaging, and eating a…
Condition: Healthy Volunteers
Investigator: Lawrence Kegeles, MD
Status: Closed
PAID RESEARCH VOLUNTEERS NEEDED Healthy volunteers, age 18-35 years, needed for a research study. Study requirements:- 2-3 hours of clinical assessments and neurocognitive testing -1 hour MRI As a participant you will receive: $100 for the MRI; $10/ hour for other testing; participants can make up to $200.00 For further information about the study and your…
Condition: Psychiatric Disorders / Depression
Investigator: Randy Auerbach, PhD
Status: Closed
We are seeking adolescents ages 13-17 to participate in a study on anhedonia. Anhedonia is the reduced ability to feel pleasure or enjoy things, and is a key feature of depression and other mental illnesses. If you believe your child is experiencing anhedonia, they may be eligible to participate in this study. If your child participates in this study, we…
Condition: Healthy Volunteers
Investigator: Billy Caceres, PhD, RN
Status: Closed
The goal of this study is to conduct interviews with lesbian, gay, bisexual, transgender, and queer (LGBTQ) adults ages 40-64 years to explore sources of stress, stress management techniques, and heart disease risk behaviors (such as smoking). We will also identify preferred modalities for a stress management intervention to reduce heart disease risk in…
Condition: Psychiatric Disorders
Investigator: Ari Shechter, PhD
Status: Closed
We are currently looking for men and women, age 18-65 y, to participate in a sleep study. To participate you must have experienced insomnia (difficulty falling asleep, staying asleep, or experiencing sleep that is unrefreshing) for at least 1 month. This is a 2-phase outpatient and inpatient study. We will test 2 different non-drug based methods to improve…
Condition: Healthy Volunteers
Investigator: Yuval Neria, PhD
Status: Closed
Emerging research has demonstrated a relationship between visual attention patterns and anxiety disorders, including PTSD. This study is designed to examine these visual attention patterns using eye-tracking A simple device that monitors eye-movements. The study included two sessions conducted approximately 1 week apart, each no longer than 1 hour. In both…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, MD
Status: Closed
Antibodies are one of the natural ways that our bodies fight or prevent infection. Were testing an antibody to find out if its safe, if they don't make people feel uncomfortable, how these study antibodies move throughout the body, and to measure antiviral activity. You cannot get HIV from the study antibody. Firstly, request to be contacted by our…
Condition: Healthy Volunteers
Investigator: Micaela Martinez, PhD
Status: Closed
How does the light we experience in day-to-day life affect our body clock? Interested in joining a new project to help scientists at Columbia University understand how light pollution and light-at-night affects our body clock? You or your child may be eligible to participate. The study involves wearing a small light sensor on a lanyard and a temperature…
Condition: Healthy Volunteers
Investigator: Marla Hamberger, PhD
Status: Closed
The purpose of this project is to develop a set of word finding or naming tests for adults, ages 66 and above. The main task involves naming pictures of common objects (e.g. broom), or naming items when given a description (e.g. "what children ride to school in"). There are some other tasks as well such as single word reading, number repetition,…
Condition: Healthy Volunteers
Investigator: Daphna Shohamy, PhD
Status: Closed
The Learning Lab at Columbia University is conducting computer based behavioral studies to address fundamental questions regarding the nature of learning, memory, and decision making. Specifically, we will use behavioral methods to investigate the extent to which learning, memory and decision making may be modulated by factors such as novelty, trial-by-…