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Displaying 1 - 200 of 253
Condition: Healthy Volunteers
Investigator: Steven Kushner, MD, PhD
Status: Currently Recruiting
As an academic medical center, Columbia University is committed to improving patient and population health through research. One way this work is supported is through the Columbia University Biobank (CUB), a secure collection of biological samples and health data that helps researchers better understand disease and develop new treatments. Researchers at…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Currently Recruiting
The overall goal of this project is to determine whether the timing of your meals and sleep influences health. We are looking for healthy adults aged 30 and older to participate in a sleep study. Participants must be willing to keep a written food and sleep record for 7 consecutive days. Participants who complete this study will receive a total compensation…
Condition: Healthy Volunteers
Investigator: Ronald Silverman, PhD
Status: Currently Recruiting
The Department of Ophthalmology is conducting an NIH-funded study of 3D ultrasound imaging of the eye, including the vitreous and optic nerve. We are interested in normal subjects without eye disease and individuals with vitreous floaters. The total duration of the exam is approximately 30 minutes. Participation is voluntary and no financial compensation is…
Condition: Healthy Volunteers
Investigator: Kiyohito Iigaya, PhD
Status: Currently Recruiting
Our lab is conducting a series of research studies investigating people's memory and decision-making. As a healthy study participant, you will be asked to complete a set of self-report questionnaires probing demographics and personality traits, followed by a number of computer-based tasks. Study participants earn between $15/hour for their time. The…
Condition: Healthy Volunteers
Investigator: Kiyohito Iigaya, PhD
Status: Currently Recruiting
Our lab is conducting a magnetic resonance imaging (fMRI) study to investigate people's memory and decision-making. We are looking for people between the ages of 18 and 60 to be healthy study participants. In this study you will be asked to complete a set of self-report questionnaires probing demographics and personality traits, followed by a number of…
Condition: Healthy Volunteers
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are conducting a research study on how insulin controls blood sugar in both healthy people and those at risk of type 2 diabetes. We are seeking adult volunteers, aged 18-65, who have body mass indices either in the lean range (18-25 kg/m2) or in the obesity range (30-45 kg/m2) but who do not have prediabetes or diabetes. Participants will undergo a…
Condition: Cancer / Leukemia
Investigator: Nobuko Hijiya, MD
Status: Currently Recruiting
This study will enroll with children, adolescents and young adults that are less than 22 years old that have returned or 'relapsed' acute myeloid leukemia (AML) diagnoses. Within this group, the study is also targeting those are also unable to receive additional chemotherapy treatments containing anthracycline, which is a type of antibiotic that…
Condition: Healthy Volunteers
Investigator: Daniel Javitt, MD, PhD
Status: Currently Recruiting
The Division of Experimental Therapeutics in conducting a research study to explore how an experimental procedure, known as transcranial interference stimulation (tIS), affects the brain's ability to process visual information, including recognizing faces. The procedures in this study include 1) interviews, 2) behavioral tests of your ability to detect…
Condition: Healthy Volunteers
Investigator: Brooke Aggarwal, EdD, MS, FAHA
Status: Currently Recruiting
Women ages 40-65 years may be eligible to participate in a survey about their sleep patterns, stress, and risk factors for heart disease. If you are interested or would like more information, please email us at researchgoesredsurvey@gmail.com.
Condition: Healthy Volunteers
Investigator: Keith Diaz, PhD
Status: Currently Recruiting
U.S. Adults spend on average 11 to 12 hours a day sitting. Daily sedentary behavior is strongly associated with the risk of heart disease. The purpose of the BREAK II research study is to answer two questions: (1) How frequently should periods of prolonged sedentary time be interrupted? and (2) What is the appropriate duration or length of time of these…
Condition: Healthy Volunteers
Investigator: Eldad Hod, MD
Status: Currently Recruiting
We are studying the effects of blood donation. If you are considering donating blood at the next school blood drive, please contact us to determine eligibility. You may qualify for participation whether or not you successfully donate blood and you will be compensated monetarily for your time.
Condition: Healthy Volunteers
Investigator: Marla Hamberger, PhD
Status: Currently Recruiting
We are looking for healthy participants. The purpose of this project is to develop a set of word finding or "naming" tests for Bilingual English-Spanish speakers, ages 35-85. The main tasks involve naming pictures of common objects (e.g. broom) or naming items when given a description (e.g. "what children ride to school in"). There are…
Condition: Healthy Volunteers
Investigator: Dritan Agalliu, PhD
Status: Currently Recruiting
The aim of this study is to understand the mechanisms of secondary effects of traumatic brain injury on the blood-brain barrier and to understand the biochemical differences in the blood of people with Alzheimer's disease and the volunteer group. We will compare biochemical blood differences between a healthy group and traumatic brain injury patients…
Condition: Healthy Volunteers
Investigator: Lila Davachi, PhD
Status: Currently Recruiting
The Davachi Lab is currently recruiting to investigate how individuals process and experience everyday events. The current study involves completing two weeks of "daily diary" survey entries that inquire about your daily experiences, such as such as where you went, what emotions you experienced, or what activities you engaged in. This study is…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Currently Recruiting
We are currently looking for healthy, nonsmoking adults ages 40-65 yrs who are dissatisfied with their sleep to participate in a sleep study. Participants should find their sleep not refreshing but not taking external sleep aids. Participants must be willing to eat a specific food for 2 periods of 4 weeks each. Compensation of up to $700 will be provided…
Condition: Healthy Volunteers
Investigator: Sarah Herzog, PhD
Status: Currently Recruiting
We are conducting a study on depression and suicide risk, and participants can earn up to $300 for taking part. Suicide rates in the U.S. are rising, and new treatments are urgently needed. This study focuses on the brain chemical glutamate, which may play an important role in mood and mental health. We will compare glutamate levels at rest and during…
Condition: Healthy Volunteers
Investigator: Jon Freeman, PhD
Status: Currently Recruiting
The Social Cognitive & Neural Sciences Lab at Columbia University's Department of Psychology is conducting a brain imaging study, which will take place over the next 1-3 months. You will be compensated for your time and receive a free video of your brain! We are flexible in scheduling convenient times for you to come in. The study will involve a 2-…
Condition: Healthy Volunteers
Investigator: Julie Herbstman, PhD, MSc
Status: Currently Recruiting
You are invited to participate in a research study to understand how environmental exposures during pregnancy influence the health and development of children. This study will begin at pregnancy and follow your child through age 11. A trained research worker will work with you and your child, administering questionnaires to you and developmental evaluations…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Currently Recruiting
We are currently looking for healthy nonsmokers, ages 18-49yrs who are satisfied with their sleep to participate in a sleep study. Participants should typically sleep 7-9 hours/night without external sleep aids. Participants must be willing to change their sleep schedule for approximately 4 weeks. Compensation of up to $1000 will be provided for completing…
Condition: Healthy Volunteers
Investigator: Catherine Clelland, PhD
Status: Currently Recruiting
This research study aims to obtain a greater understanding of the causes of cognitive decline in Alzheimer's disease. We are currently enrolling male and female participants (ages 55 years and older) with Alzheimer's disease, mild cognitive impairment, or healthy controls. Enrolled participants with undergo a small blood draw (about 8 teaspoons)…
Condition: Healthy Volunteers
Investigator: Richard Francis, MD, PhD
Status: Currently Recruiting
This is a Blood Donor Study being conducted at Columbia University Irving Medical Center - New York Presbyterian Hospital. We are interested in recruiting males between the ages of 18-65 who are of African, Asian, Hispanic, Middle Eastern, or Mediterranean descent. The purpose of this research study is to determine whether genetic factors in your DNA affect…
Condition: Healthy Volunteers
Investigator: A. Benjamin Srivastava, MD
Status: Currently Recruiting
Do you ever wonder how brains work? You can earn compensation for completing a study investigating human brain function by having a brain scan. You can earn up to $220 for your participation.
Condition: Healthy Volunteers
Investigator: Michael Lipton, MD PhD
Status: Currently Recruiting
The Lifespan Study uses neuroimaging, cognitive tests, and genomics to explore how the brain's structure and function change throughout life. We are creating a database of typical brain imaging data to study age-related changes. This database will support research, clinical studies, and the creation of new tools for measuring brain health. The Lifespan…
Condition: Healthy Volunteers
Investigator: Norman Kleiman, PhD
Status: Currently Recruiting
We are seeking female menstruating subjects to determine the level of PFAS present in feminine hygiene products. We will ask subjects to provide both a used and unused tampon to measure levels of these chemicals.
Condition: Cancer / Leukemia
Investigator: Nobuko Hijiya, MD
Status: Currently Recruiting
This study is called a screening study and the purpose of this study to find better ways to diagnose and treat leukemia that has come back after treatment or difficult to treat. Bone marrow, blood, and medical information about cancer and treatment will be collected. The results from this screening study may give other information about leukemia that is…
Condition: Healthy Volunteers
Investigator: David Welch
Status: Currently Recruiting
We are seeking subjects for measurements of skin properties using non-invasive devices. Measurements will be made to the forehead and forearm of the participant. These measurements will be performed during a single visit lasting approximately 1 hour.
Condition: Cancer / Leukemia
Investigator: Nobuko Hijiya, MD
Status: Currently Recruiting
This is a phase 1 study for participants with relapsed/refractory acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or juvenile myelomonocytic leukemia (JMML) diagnosis. This study will observe the safety, side effects, and best dose of Imetelstat as an investigational drug, or drug that is not approved by the Food and Drug Administration (FDA…
Condition: Healthy Volunteers
Investigator: Kiyohito Iigaya, PhD
Status: Currently Recruiting
Our lab is conducting a series of research studies investigating people's behavior. We are looking for people between the ages of 18 and 60. As a healthy study participant, you will be asked to complete a set of self-report questionnaires probing demographics and personality traits, followed by a number of computer-based tasks. Study participants earn…
Condition: Healthy Volunteers
Investigator: Philip De Jager, PhD
Status: Currently Recruiting
Genes and Environment in MS (GEMS) is a longitudinal cohort study investigating how genetics and environment can lead to the onset of Multiple Sclerosis. We are recruiting first-degree relatives (siblings, parents, and children) of people who have been diagnosed with MS. This study involves the collection of magnetic resonance imaging (MRI) of the brain,…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Currently Recruiting
We are currently looking for healthy, nonsmoking adults ages 25-65yrs who are dissatisfied with their sleep to participate in a sleep study. Participants should find their sleep not refreshing but not taking external sleep aids. Participants must be willing to eat different foods for two periods of 4 days and undergo testing over a 24-hour period at the…
Condition: Healthy Volunteers
Investigator: Guillermo Horga, MD, PhD
Status: Currently Recruiting
In this study, we are trying to learn more about the symptoms of psychosis, specifically to learn how alterations in the brain may produce certain experiences (including voice hearing or auditory hallucinations) that are common in people with psychosis or schizophrenia. The study involves clinical interviews, computer tests, and magnetic resonance imaging (…
Condition: Healthy Volunteers
Investigator: Julian Agin-Liebes, MD
Status: Currently Recruiting
We are looking for participants for a study on the role of immune response in Parkinsons disease (PD) and Alzheimer's disease (AD). We are inviting people WITH PD, WITH AD, WITH amnestic Mild Cognitive Impairment or WITHOUT PD or AD to come and participate. We will be doing several questionnaires, a motor exam, and a short cognitive assessment, in…
Condition: Healthy Volunteers
Investigator: Scott Small, MD
Status: Currently Recruiting
For over 30 years, The Columbia University Alzheimer's Disease Research Center (ADRC) has worked with thousands of participants who have helped provide important insights into how the brain ages and why Alzheimer's disease may develop. We are actively recruiting adults 65 years of age and older who share our commitment to be part of this…
Condition: Healthy Volunteers
Investigator: Jonathan Overdevest, MD, PhD
Status: Currently Recruiting
The Columbia Otolaryngology Department is interested in understanding how sense of smell relates to memory and neurocognition. Participation will involve answering a series of questionnaires, completing a formal evaluation of your smell with standardized measurements, and complete short smell and memory games. You can participate in this study if you are…
Condition: Healthy Volunteers
Investigator: Patrick Lao, PhD
Status: Currently Recruiting
The purpose of this study is to determine how inflammation is related to changes in the brain that occur during the progression of Alzheimer's disease. If you are eligible for this study, we will ask you to complete 3-4 study visits over the course of about 5 months. Participation includes memory testing, a blood draw, MRI, PET scans, and a lumbar…
Condition: Healthy Volunteers
Investigator: Lila Davachi, PhD
Status: Currently Recruiting
The Davachi Lab is currently running research studies to investigate information processing. These behavioral studies may involve looking at negative, neutral, and positive images on a computer screen (such as objects, faces, or scenes) and/or listening to negative, neutral, and positive auditory sounds (such as tones with varied pitches or human-produced…
Condition: Healthy Volunteers
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are recruiting volunteers, aged 18-70, for a research study on the buildup of excessive liver fat ("fatty liver disease") in people with or at risk for type 2 diabetes because their bodies are resistant to the actions of the blood sugar-lowering hormone, insulin. To do this, we seek to temporarily induce or accentuate insulin resistance in 14…
Condition: Healthy Volunteers
Investigator: Joshua Cook, MD, PhD
Status: Currently Recruiting
We are seeking adult volunteers with body mass index in the obesity range (30-45 kg/m2) to come in for a single study visit where they answer some health questions and have a small volume of blood drawn (25 cc/1.7 tbsp). We will measure levels of the blood sugar-lowering hormone insulin as well as glucose (sugar), certain fats, and other molecules related…
Condition: Healthy Volunteers
Investigator: Pamela Freda, MD
Status: Currently Recruiting
Growth hormone and insulin-like growth-factor 1 (IGF-1) are two hormones that are very important to human growth and metabolism. In disorders of GH and IGF-1 excess and deficiency, significant growth and metabolic abnormalities can develop. This study investigates the effects of GH on the appetite-stimulating hormone AgRP (agouti-related peptide) and the…
Condition: Healthy Volunteers
Investigator: Yufeng Shen, PhD
Status: Currently Recruiting
Study examining the genetic causes of birth defects
Condition: Healthy Volunteers
Investigator: Muredach Reilly, MD
Status: Currently Recruiting
As an academic medical center, we are always working to improve patient and population health. One way that research is supported here is through the Columbia University Biobank (CUB). A biobank is a collection of biological samples and health data gathered during a patient's medical care. Participants in a biobank help researchers find treatments and…
Condition: Healthy Volunteers
Investigator: Daniel Wolpert, PhD
Status: Currently Recruiting
The Sensorimotor Learning Lab at Columbia University is conducting behavioral studies of how our brains control movement. We are looking for volunteers to take part in experiments involving moving in virtual reality, interacting with robotic interfaces and other movement tasks. All the experiments are noninvasive and have been approved by the Columbia IRB.…
Condition: Healthy Volunteers
Investigator: David Brenner, PhD
Status: Currently Recruiting
The purpose of this study is to use blood from healthy people to develop a test to see if people have been exposed to radiation. Between 2 and 3 tablespoons of blood will be drawn from your arm. The blood will be tested with radiation in our laboratory at the Center for Radiological Research at the Columbia University Irving Medical Center. We will measure…
Condition: Healthy Volunteers
Investigator: Christine Kim Garcia, MD
Status: Currently Recruiting
The purpose of this study is to identify genetic causes of lung diseases and to develop a research repository so that we can better understand, prevent and treat these conditions. You have been asked to join this study as a healthy control. Even though you do not have lung disease, your sample is valuable to us. For example, you may be related to someone…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Currently Recruiting
We are looking for individuals 18 to 65 years old who are interested in learning more about HIV prevention and biomedical research studies. We will ask you to complete a brief questionnaire to find out if we can schedule you for a one-on-one, 1.5-hour education visit to learn about the research we do. The education visit will help you decide if you want to…
Condition: Healthy Volunteers
Investigator: Philip De Jager, PhD
Status: Currently Recruiting
The purpose of this study is to establish a collection of biological fluids and associated data from healthy individuals to determine how genetic and environmental variation affects the immune system. Study visits consist of taking vitals and collecting biological fluids, such as blood. You will be compensated for participating in this study.
Condition: Healthy Volunteers
Investigator: Philip De Jager, PhD
Status: Currently Recruiting
The Snapshot study aims to understand brain and spinal cord aging in healthy individuals and individuals with multiple sclerosis (MS). We aim to identify new tools that will help us to achieve successful brain aging in the general population and in people with an underlying autoimmune disease. A critical aspect of this study is that we are looking for…
Condition: Healthy Volunteers
Investigator: Pamela Freda, MD
Status: Closed
We are looking for healthy people ages 18-70 to study inflammation of fat tissue. Participation includes: fasting over-night before the visit (12 hrs), a blood sample, a DXA test of body composition, an MRI test of body composition, a brief health history questionnaire, height, weight, blood pressure, pulse measurements, and a fat biopsy. For the fat biopsy…
Condition: Healthy Volunteers
Investigator: Pamela Freda, MD
Status: Closed
The purpose of the study is for us to better understand how acromegaly affects bone structure .This study is for particpants who do not have acromegaly. The purpose of this study is to see if there are any differences in bone structure in patients with acromegaly compared to patients with cured acromegaly or without a history of acromegaly. Participants…
Condition: Healthy Volunteers
Investigator: Priyanka Ahimaz
Status: Closed
The purpose of this study is to develop written materials and infographics as resources to guide in the understanding of genetics, genomics, and how it relates to one's health and the health of their community. Participants will take part in a 1 hour video call to review educational materials and share your thoughts, emotions, and suggestions for…
Condition: Healthy Volunteers
Investigator: Jon Freeman, PhD
Status: Closed
The Social Cognitive & Neural Sciences Lab at Columbia University's Department of Psychology is conducting a brain imaging study, which will take place over the next 1-2 months. You will be compensated for your time and receive a free video of your brain! We are flexible in scheduling convenient times for you to come in. The study will involve a 2-…
Condition: Insomnia
Investigator: Carmela Alcantara, PhD
Status: Closed
Trouble sleeping? Do you speak Spanish and identify as Hispanic or Latino/a? Dormir Mejor team is recruiting for our study testing a smartphone application that delivers cognitive behavioral treatment for insomnia (CBT-I) among Spanish-Speaking Latino/as. To participate, fill out a study interest form by following the link: https://tinyurl.com/sleepdm or…
Condition: Healthy Volunteers
Investigator: Alfredo Spagna, PhD
Status: Closed
The purpose of this research study is understand how three human abilities, attention, visual conscious perception, and imagination, interact with each other to create our behavior.The procedures in this study require collecting your performance data (how fast and accurate you are) in responding to visual stimuli presented on the screen and / or auditory…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Closed
The overall goal of this project is to determine whether the timing of your meals influences health. We are currently looking for healthy, non-smoking, men and women to participate in this study. You must regularly sleep at least 7-9 hours/night and regularly eat close to wake time. In addition, you must be willing to come to Columbia University Irving…
Purpose 365: Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)
Condition: Healthy Volunteers
Investigator: Ellen Morrison, MD, MPH
Status: Closed
PrEP (Pre-Exposure Prophylaxis) is medication that is taken to help prevent HIV infection even if they are exposed to HIV. Research is continuing to find other, more convenient types of PrEP. This study is important because people in many areas of New York City have high rates of HIV acquisition, but use of prevention medication (PrEP) is low. The purpose…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
This clinical research study is seeking healthy individuals ages 18 to 65 who do not have HIV to help researchers understand how the body's immune system responds to three investigational antibodies (VRC07-523LS, PGT121.414.LS, and PGDM1400LS) against HIV when given in different combinations and doses. This is a Phase 2 study, which means that the…
Condition: Healthy Volunteers
Investigator: Sharon Wardlaw, MD
Status: Closed
The goal of this project is to understand why bariatric surgery is such an effective treatment for obesity with a focus on brain mechanisms. Cerebrospinal fluid neuropeptides, hormones, and protein levels will be measured in subjects before and after bariatric surgery as compared with subjects before and after diet-induced weight loss. Participants in the…
Condition: Healthy Volunteers
Investigator: Gaurav Patel, MD, PhD
Status: Closed
The Dynamic Social Cognition Lab (DSCLab) is currently running a research study to map the parts of the brain involved in how we process social situations. This study involves a combination of clinical, behavioral and magnetic resonance imaging (MRI) sessions. The clinical and behavioral sessions include questionnaires about yourself and your history as…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
This trial is testing two experimental vaccines for HIV called DV700P-RNA and DV701B1.1-RNA. This trial is a Phase 1 study testing whether these vaccines are safe to use in people and can be taken comfortably, as well as how the immune system responds to the vaccines.Both vaccines are made using messenger ribonucleic acid (mRNA) technology. mRNA is a piece…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The HIV Vaccine Trials Network, Division of AIDS, and Columbia University Irving Medical Center are conducting a trial to learn about the safety and effectiveness of two new experimental HIV vaccines. This is a first-in-human phase 1 clinical trial where we will be testing 2 study vaccines, CH505M5 N197D mRNA-gp160 and CH505 TF mRNA-gp160. The goal is to…
Condition: Healthy Volunteers
Investigator: S. Zev Williams, MD, PhD
Status: Closed
Researchers at Columbia are looking at the changes that happen in the placenta when people become pregnant. Participation in this study involves a blood draw at three time points. Participants will be paid $50 at each time point. Participants who complete all three time points will receive bonus compensation.
Condition: Healthy Volunteers
Investigator: Lila Davachi, PhD
Status: Closed
The Davachi Lab is currently running research studies to investigate information processing. These behavioral studies may involve looking at neutral images on a computer screen (such as objects, faces, or scenes) and/or listening to neutral auditory sounds (such as natural ambiance or artificial tones), and making judgments about them. In this study,…
Condition: Healthy Volunteers
Investigator: Daichi Shimbo, MD
Status: Closed
The measurement of blood pressure used to determine if a person has high blood pressure (also known as hypertension) and whether their blood pressure is controlled while taking medications that lower blood pressure. For many people, blood pressure levels are different when measured in a providers office versus during normal daily activities outside of the…
Condition: Healthy Volunteers
Investigator: Marwah Abdalla, MD
Status: Closed
The Center for Behavioral Cardiovascular Health (CBCH) is conducting a research study to examine the impacts on blood pressure when it is measured with and without someone in the room with you. Two-part screening to determine eligibility for this study involves a) answering questionnaires and b) measuring your arm circumference. Participation in the…
Condition: Healthy Volunteers
Investigator: Ellen Morrison, MD, MPH
Status: Closed
PrEP (Pre-Exposure Prophylaxis) is medication that is taken to prevent HIV if a person is exposed to HIV. Research is ongoing to develop PrEP medications that may be both convenient and effective. This study is important because people who inject drugs face multiple overlapping individual, social, legal, and structural challenges contributing to a…
Condition: Healthy Volunteers
Investigator: Adam Brickman, PhD
Status: Closed
The purpose of this study is to better understand how vascular health affects your thinking abilities. We hope that these findings will ultimately lead to treatments aimed to reduce cognitive impairment and dementia. We are actively recruiting adults between the ages of 65 and 90 who note some decline in memory or thinking over the past 3 years and who are…
Condition: Healthy Volunteers
Investigator: Ellen Morrison, MD, MPH
Status: Closed
PrEP (Pre-Exposure Prophylaxis) is medication that is taken to prevent HIV if a person is exposed to HIV. Research is ongoing to identify PrEP medications that are both convenient and effective. This study is important because women in many areas of New York City have high rates of HIV coupled with low utilization of PrEP. The purpose of HPTN 102/Purpose 3…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The HIV Vaccine Trials Network (HVTN) and Columbia University Irving Medical Center (CUIMC) are conducting a study to learn about the safety and effectiveness of an experimental HIV vaccine. The study vaccine is a protein vaccine called N332-GT5 gp140. It includes a manmade protein that looks like a protein found on the outside of HIV. The study vaccine is…
Condition: Healthy Volunteers
Investigator: Ellen Morrison, MD, MPH
Status: Closed
Come and talk with us about HIV prevention! HPTN 113-01/DUO is a series of 3 focus group discussions with young Latino/e/x cisgender men and gender nonbinary persons assigned male at birth (AMAB), who have sex with men. The focus groups will be conducted in English or Spanish, include 5-10 people, and be audio-recorded. Participants will be asked to give…
Condition: Healthy Volunteers
Investigator: Elizabeth Oelsner, MD, MPH
Status: Closed
This study is called the COVID-19 Lung Microvascular and Parenchymal Sequelae (LUNG MaPS) Study. The purpose of the study is to learn about the effects of COVID-19 infections on the lungs and heart, and to improve our understanding of why some COVID-19 patients experience ongoing symptoms, or what is often called "long COVID." Hundreds of…
Condition: Healthy Volunteers
Investigator: Lauren Houghton, PhD
Status: Closed
We are conducting a series of focus group sessions to investigate the attitudes and opinions of young Black women regarding breast cancer, breast cancer risk, and biomarker-based screening to inform current breast cancer screening guidelines.
Condition: Healthy Volunteers
Investigator: Christine Kim Garcia, MD
Status: Closed
The purpose of this study is to identify genetic causes of lung diseases and to develop a research repository so that we can better understand, prevent, and treat these conditions. You have been asked to join this study as a healthy control. Even though you do not have lung disease, your sample is valuable to us because you are related to someone with lung…
Condition: Healthy Volunteers
Investigator: Brooke Aggarwal, EdD, MS, FAHA
Status: Closed
High school students ages 14-18 and their parent(s) may be eligible to participate in a 12-week (consisting of a 6-week pre-pilot and 6-week pilot) sleep health education program.
Condition: Healthy Volunteers
Investigator: Philip De Jager, PhD
Status: Closed
The purpose of this study is to determine whether different genes are related to the amount of immune cell activity that occurs in the brain in patients with Alzheimer's disease. Participation in this study involves memory testing, a blood draw, MRI, and three PET scans. The second PET scan will involve putting a catheter in your wrist to draw blood…
Condition: Cancer / Leukemia
Investigator: Nicole Lamanna, MD
Status: Closed
This study will be performed to determine if Panzyga (the study drug) can help with preventing infections in patients who have chronic lymphocytic leukemia (CLL). Panzyga is a study drug administered via injection into the vein, which contains human antibodies also called immunoglobulins. It is manufactured by Octapharma. Your participation in this clinical…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Closed
Study of shift workers: We are seeking metabolically-healthy women between the ages of 20 and 55 who work day or night shifts (8 hours or more) to participate in a study at CUIMC/NYP. This study will include 4 separate visits (once per week) to the inpatient unit of Presbyterian Hospital, with each visit lasting a full 24 hours. During the visits, all meals…
Condition: Healthy Volunteers
Investigator: Dani Dumitriu, MD, PhD
Status: Closed
This study aims to understand the impact of the COVID-19 pandemic on mother and infant health outcomes in pregnant women delivering at NewYork-Presbyterian Morgan Stanley Children's Hospital or Allen Pavilion Hospital. Data will be collected through online surveys, video visits, and electronic health records.
Condition: Healthy Volunteers
Investigator: Henning Schulzrinne, PhD
Status: Closed
We (the Internet Real-Time Lab (IRT) in the Department of Computer Science at Columbia University) are looking for participants in an experiment evaluating the effects of audio impairments such as background noise, delay, and loss on the intelligibility of first responder communication (firefighters, ambulance, police). The experiment will take place in a…
Condition: Healthy Volunteers
Investigator: Akiva Mintz, MD, PhD
Status: Closed
Neurodegenerative diseases are conditions where the brain cells break down, causing mental and/or physical impairment. Alzheimer's Disease is a neurodegenerative disorder that affects millions of individuals and causes irreversible memory loss and cognitive impairment. Amyotrophic lateral sclerosis is also and incurable disorder that causes patients…
Condition: Healthy Volunteers
Investigator: Sharon Sanz Simon, PhD
Status: Closed
The purpose of this study is to investigate the effect of a web-based (remote, at home) computerized cognitive training protocol on cognitive performance in cognitively healthy older adults. The training will involve multi-tasking in a simulation of daily life situation. If you are eligible, you will be asked to complete 15 web-based sessions, 3 times a…
Condition: Healthy Volunteers
Investigator: Sharon Mannheimer, MD
Status: Closed
We are looking for adult volunteers to help us see if the FDA-approved Bexsero meningitis B vaccine can prevent people from getting gonorrhea infections. There are over 580,000 cases of gonorrhea diagnosed annually in the United States. Gonorrhea infections can significantly affect short and long-term reproductive health and contribute to increasing HIV…
Condition: Cancer / Leukemia
Investigator: Luca Szalontay, MD
Status: Closed
The purpose of this study is to find the best dose of Quizartinib that can be given safely with chemotherapy in children and young adults with acute myeloid leukemia (AML) which has come back or has not responded to the standard therapy. Quizartinib will be given by mouth once a day from Day 6 through Day 28. It will be given in combination with…
Condition: Healthy Volunteers
Investigator: Rebecca Straus Farber, MD
Status: Closed
We are currently recruiting healthy individuals to take part in our research on the effects of probiotics. Our goal is to better understand how the health of the gut microbiome influences the immune system.
Condition: Healthy Volunteers
Investigator: Karen Bell, MD
Status: Closed
We are seeking men & women, ages 55 to 80, who have preclinical Alzheimer's disease for a 216-week treatment, multi-center, double-blind, placebo-controlled, parallel-treatment arm study to determine whether the BAN2401 study drug will reduce the risk of developing Alzheimer's disease. The study participant will receive MRI, and PET scans and…
Condition: Healthy Volunteers
Investigator: Lawrence Honig, MD, PhD
Status: Closed
The Longitudinal Early-onset Alzheimer's Disease Study (LEADS) is a natural history, non-treatment study designed to look at disease progression in individuals with early onset cognitive impairment . Clinical/cognitive, imaging, biomarker, and genetic characteristics will be assessed across two cohorts: early onset Alzheimer's Disease (EOAD)…
Condition: Healthy Volunteers
Investigator: Sarah O'Shea, MD
Status: Closed
The Parkinson's Progression Markers Initiative (PPMI) seeks to uncover insights into Parkinson's disease (PD) onset and progression that could transform how we diagnose, treat, and potentially prevent PD. PPMI has already contributed to a new understanding around disease biology and experience, and its findings and design have led to more…
Condition: Healthy Volunteers
Investigator: Chunhua Weng, PhD
Status: Closed
Researchers at Columbia University Irving Medical Center are asking for your help. We are recruiting people 3-75 years of age. We are looking at how a report that contains information about genetic risk for some health conditions may help you and your care providers make decisions about your health. You may be eligible if you receive care at Columbia…
Condition: Healthy Volunteers
Investigator: Joshua Cook, MD, PhD
Status: Closed
We're conducting a research study on how much insulin is needed to control blood sugar in people who are made temporarily resistant to insulin's effects. Insulin is the main hormone (chemical signal) that the body uses to lower the levels of sugar in the blood. We are interested in looking at insulin levels because we think that lowering insulin…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The purpose of the study is to test an experimental HIV vaccine. The study vaccine is made from two parts: a man-made piece of protein that looks like a protein found on the outside of HIV and an adjuvant. An adjuvant is a substance that helps the immune system respond better. The study will see if the protein and two different amounts of the same adjuvant…
Condition: Healthy Volunteers
Investigator: Daphna Shohamy, PhD
Status: Closed
We are researchers in the Shohamy Lab studying how learning changes across the lifespan. We are looking for participants ages 11-15 for an MRI study. During the MRI study, your child will play computer games and answer questions about their thoughts and feelings. They will also play some games inside an MRI scanner. The total study takes three hours. This…
Condition: Healthy Volunteers
Investigator: Ana Navas-Acien, MD, PHD, MPH
Status: Closed
The use of electronic cigarettes, also known as e-cigs or vaping, has increased among former smokers and young adults who have never smoked. Relatively little is known, however, about their health effects (whether they are adverse, have no effect, or are beneficial). The purpose of this research study is to evaluate (1) the association of e-cig use with…
Condition: Cancer / Leukemia
Investigator: Nobuko Hijiya, MD
Status: Closed
The purpose of this study is to find out if the drugs called Nivolumab and 5-Azacytidine can be given safely in children and young adults with Acute Myeloid Leukemia (AML) which has come back after treatment or has not responded to standard therapy. These drugs are thought to work by turning on genes that limit the growth of cancer cells. The study drugs…
Condition: Healthy Volunteers
Investigator: Daichi Shimbo, MD
Status: Closed
We are conducting a research study in adults to test whether blood pressure (BP) measured in a clinic setting without a technician present is comparable to blood pressure levels while awake outside of the clinic on an Ambulatory Blood Pressure Monitoring (ABPM) device. We will also test whether asleep blood pressure can be accurately determined using a home…
Condition: Healthy Volunteers
Investigator: Jon Giles, MD
Status: Closed
We are inviting patients without autoimmune disorders to help us compare to rheumatoid arthritis patients with inflammation in soft tissues. With a combination of blood work, a full-body FDG PET-CT scan, questionnaires, and a soft tissue biopsy (from an area around the belly button), we hope to see how tissue inflammation interacts with these multiple areas…
Condition: Healthy Volunteers
Investigator: Julian Agin-Liebes, MD
Status: Closed
FoxBioNet ECV-004 is an observational study sponsored by the Michael J. Fox Foundation for Parkinson's Research. The purpose of this study is to investigate a gene called LRRK2. Mutations in the LRRK2 gene are associated with Parkinson's disease (PD), and mutation carriers have greater LRRK2 protein activity. The goal of this study is to identify…
Dormir Mejor Study: Digital Cognitive-Behavioral Therapy for Insomnia in Spanish-Speaking Latinas/os
Condition: Insomnia
Investigator: Carmela Alcantara, PhD
Status: Closed
Trouble sleeping? Do you Identify as Latino/a and speak Spanish? Dormir Mejor team is recruiting for our study that is testing a digital cognitive behavioral therapy treatment for insomnia (CBT-I) among Spanish-speaking Latinos using a phone application! You may be eligible if: identify as Latina/o, speak Spanish, are 18 years old or older, and have…
Condition: Healthy Volunteers
Investigator: Ari Shechter, PhD
Status: Closed
We are seeking healthy female Black Non-Hispanic and White Hispanic control participants who are of normal weight (BMI 18.5-24.9) for a study that is being held by the New York Obesity Nutrition Research Center at Columbia University Medical Center (CUMC) and focuses on eating behavior. In this study, you will be asked to visit CUMC to complete several…
Condition: Healthy Volunteers
Investigator: Lena Mamykina, PhD
Status: Closed
Seeking participants for a study about how individuals prefer to receive nutrition recommendations to support health management and preferences for visualizing health data. Participants will be invited to complete a 60-minute session to answer questionnaires and evaluate different styles of nutrition recommendations. Alternatively, they will complete one 60…
Condition: Healthy Volunteers
Investigator: Ali Gharavi, MD
Status: Closed
The All of Us Research Program has a simple mission. We want to speed up health research breakthroughs. To do this, we are asking one million people to help us lead the way in discovering better care for all of us. The All of Us Research Program is a large research program. The goal is to help researchers understand more about why people get sick or stay…
Condition: Healthy Volunteers
Investigator: Elizabeth Shane, MD
Status: Closed
The goal of this study is to learn whether treatment with a safe, commonly used drug called ATENOLOL prevents bone loss in women after menopause. Who Qualifies? Healthy post-menopausal women who are between the ages of 50 and 75. You may not be eligible if you have certain medical conditions. What's Involved? If you are eligible, you will be assigned…
Condition: Healthy Volunteers
Investigator: Nour Makarem, PhD
Status: Closed
We are currently looking for men and non-pregnant women aged 40 years and above to participate in an at-home study on sleep and activity patterns in relation to blood pressure and blood glucose. Participants should not have critical/severe illness and should not be on dialysis or have a pacemaker or other implanted medical device. You must be willing to…
Condition: Healthy Volunteers
Investigator: Joshua Cook, MD, PhD
Status: Closed
We are recruiting healthy volunteers, aged 18-65, for a research study on the buildup of excessive liver fat ("fatty liver disease") in people with or at risk for type 2 diabetes because their bodies are resistant to the actions of the blood sugar-lowering hormone, insulin. To do this, we seek to induce temporary insulin resistance in 10-12…
Condition: Healthy Volunteers
Investigator: Jessica Justman, MD
Status: Closed
The purpose of this study is to look for antibody evidence of mpox among the New York City community of men who have sex with men, non-binary, gender diverse, and transgender individuals. Mpox used to be called monkeypox. You do not need to have had a mpox infection or mpox vaccination to take part in this study. If you take part in the study, you'll…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
You are being asked to participate in this study because you have a myeloproliferative neoplasm (MPN) that has transformed to accelerated or blast phase. MPN is a group of diseases in which the bone marrow makes too many blood cells. The different types of MPN are myelofibrosis (MF), essential thrombocythemia (ET), or polycythemia vera (PV). Over time,…
Condition: Healthy Volunteers
Investigator: Daichi Shimbo, MD
Status: Closed
The purpose of this clinical trial is to study the relationship of stress, salt excretion, and nighttime blood pressure. Blood pressure normally has a diurnal pattern: it is highest during the day and dips during the night. The effects of psychological stress can interfere with this normal pattern and cause elevated nighttime blood pressure or reduced blood…
Condition: Healthy Volunteers
Investigator: Nancy Green, MD
Status: Closed
Add Your VOICE to Research is a brief electronic survey to understand the views of people who join research studies. Survey responses are anonymous - no one will know who has taken the survey. Eligibility requires current or recent (within the past 2 years) participation in research studies (beyond just taking a survey). Please copy the link into your…
Condition: Healthy Volunteers
Investigator: Marwah Abdalla, MD
Status: Closed
The Center for Behavioral Cardiovascular Health (CBCH) is conducting a research study to examine the impact that sleep hours have on blood pressure (BP) levels during sleep. Two-part screening to determine eligibility for this study involves a) answering questionnaires and b) documenting daily average sleep duration (how long you sleep) over the course of a…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
You are being asked to participate in this study because you have been diagnosed with a blood cancer called Acute Myeloid Leukemia (AML) with or suspected to have a specific gene mutation (TP53 mutation) for which you have not received any prior AML treatment. Tumor protein p53 (TP53) is a gene that codes for a tumor suppressor protein, which is normally…
Condition: Healthy Volunteers
Investigator: Kevin Ochsner, PhD
Status: Closed
The SCAN lab at Columbia University is seeking healthy adults (18 years or older) to participate in a paid online research study investigating emotion, memory, and social interactions in daily life. This study will take place entirely online and can be completed from your home. It will include 4 weeks (1-month) of answering surveys on your smartphone as you…
Condition: Healthy Volunteers
Investigator: Meghan Reading Turchioe, PhD, MPH, RN
Status: Closed
We are seeking adults with cardiovascular disease who identify as Black/African American or LatinX, and/or their caregivers, as well as community health workers working in primarily Black/African American or LatinX neighborhoods of NYC, to participate in a brief (30-minute) interviews over the phone or Zoom to discuss attitudes and perceptions related to…
Condition: Cancer / Leukemia
Investigator: Mark Heaney, MD, PhD
Status: Closed
The purpose of this study is to determine the optimal dose of oral CGT9486 in patients with Advanced Systemic Mastocytosis (AdvSM) and to determine the efficacy of CGT9486 at the selected optimal dose in patients with Advanced Systemic Mastocytosis (AdvSM). This includes Aggressive Systemic Mastocytosis, Advanced Systemic Mastocytosis with an Associated…
Condition: Cancer / Leukemia
Investigator: Nicole Lamanna, MD
Status: Closed
The purpose of this study is to determine the effectiveness of the study treatment- bendamustine and rituximab (BR) followed by venetoclax for 12 months. The combination of the drugs bendamustine and rituximab is a commonly used treatment for your disease. Venetoclax is an oral drug that blocks a protein called BCL-2 which is present on CLL cells. With this…
Condition: Healthy Volunteers
Investigator: Marwah Abdalla, MD
Status: Closed
The Center for Behavioral Cardiovascular Health (CBCH) is conducting a research study to examine the relationship between sleep and nighttime blood pressure levels and whether this relationship has something to do with the way our nervous system functions. Participants must speak English or Spanish and be between 25 and 60 years of age. A 5-minute online…
Condition: Healthy Volunteers
Investigator: Marcella Walker, MD
Status: Closed
Celiac disease is associated with an increased risk of osteoporosis and fractures. Men with celiac disease were found to be at higher risk for metabolic bone disease compared to women with celiac disease. The mechanisms underlying metabolic bone disease in celiac disease remain incompletely understood. The goal of this study is to assess skeletal…
Condition: Healthy Volunteers
Investigator: Kevin Ochsner, PhD
Status: Closed
The SCAN lab at Columbia University is seeking couples to participate in a paid online research study investigating socio-emotional experiences with your partner in daily life. This study will take place entirely online and can be completed from your home. It will include an eligibility screening survey, a 25 min online baseline survey, a brief review of…
Condition: Healthy Volunteers
Investigator: Dympna Gallagher, EdD
Status: Closed
The aim of this study is to estimate the surface area of the body of children using a scanner that images the surface of the body. It is being used in the fashion industry for accurate measurements to design well-fitted clothes. We want research how the scans estimate compares to current equations used in medicine. The study is recruiting children aged 3-17…
Condition: Healthy Volunteers
Investigator: Sheng-Han Kuo, MD
Status: Closed
Why? To evaluate how brain networks are affected when frequency-specific, non-invasive, brain stimulation is applied to people with ataxia or essential tremor as compared to healthy control subjects. Who? Healthy adults over the age of 40, who would like to participate as controls. What? Participation involves one clinic visit for 2-3 Hours, involving EEG…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Closed
We are currently looking for healthy, non-smoking, men and women ( age 55-75 years) to participate in an at-home sleep study. You must be willing to come to the research center once a week during the entire duration of the study (two separate 6-week periods). To participate you must regularly sleep 7-9 hours/night. Compensation up to $2000-$2400, based on…
Condition: Healthy Volunteers
Investigator: Amir Levine, MD
Status: Closed
The Columbia University Medical Center/New York State Psychiatric Institute is currently recruiting healthy volunteers with no previous diagnosis of any psychiatric disorders to provide samples and answer questionnaires. If your child is eligible, he or she will be compensated up to $110.
Condition: Cancer / Leukemia
Investigator: Ran Reshef, MD
Status: Closed
Patients who will be receiving immune effector cell (IEC) therapy for the treatment of their cancer (leukemia) are being asked to participate in this study. IEC can produce a harmful side effect called Cytokine Release Syndrome (CRS). CRS involves a release of a large amount of proteins into the bloodstream. This may cause changes in blood pressure and…
Condition: Healthy Volunteers
Investigator: Gaurav Patel, MD, PhD
Status: Closed
Our lab is conducting a series of research studies that investigate how specific brain regions are related to functioning in work, school, and in other social situations. As a study participant, you will be asked to complete clinical and neuropsychological assessments, an eye-tracking task, and a non-invasive MRI scan. Study participants earn between $15-50…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
The purpose of this study is to compare the effects, both good and bad, of magrolimab in combination with azacitidine, to those of azacitidine in combination with placebo, to find out which is better for treating patients with MDS (Myelodysplastic Syndrome). Other purposes of this study include determining the quantity of magrolimab in the blood, aspects of…
Condition: Healthy Volunteers
Investigator: Julie Franks, PhD
Status: Closed
We are conducting a study to see if offering pre-exposure prophylaxis (PrEP) together with another health service that many transgender women use or would like to use, gender-affirming hormone therapy (GAHT), improves HIV-related outcomes, as compared to offering PrEP and referring study participants to get GAHT at area health providers. This study is for…
Condition: Cancer / Leukemia
Investigator: Andrew Lipsky, MD
Status: Closed
The purpose of this study is to assess the safety, effectiveness, pharmacokinetic (PK how long the drug is in your body and how it is metabolized) and pharmacodynamics (PD where does the drug go in your body and what is its biological effect) of the study drug, GFH009, in patients with relapsed or refractory hematologic malignancies including acute myeloid…
Condition: Healthy Volunteers
Investigator: Rebecca Schnall, PhD, RN
Status: Closed
The mLab study at Columbia University is looking for young cisgender men or trans women who are 18-29 years old and have sex with guys. Eligible individuals can earn up to $170 by participating in this LGBTQ+ health study and completing 3 online surveys over the course of 1 year. See if you're eligible to participate! Questions? Text us: 347-743-0104
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
The purpose of this clinical research study is to evaluate the safety (any good or bad effects) of CYNK-001 and to assess the effects of CYNK-001 on your Acute Myeloid Leukemia (AML). Also, the study plans to determine the maximum tolerated dose (highest safe dose) of CYNK-001 and assess whether CYNK-001 can eliminate your residual (leftover) disease.…
Condition: Healthy Volunteers
Investigator: Jeremy Veenstra-VanderWeele, MD
Status: Closed
We are recruiting healthy volunteers between the ages of 13-35 to participate in a study at the New York State Psychiatric Institute to obtain biosensor date from typically developing individuals. It will involve questionnaires, eye tracking, an electroencephalogram (EEG), and electrocardiogram (ECG). There are two cohorts for this study: Cohort 1 requiring…
Condition: Healthy Volunteers
Investigator: Paula Castano, MD, MPH
Status: Closed
Nexplanon a contraceptive implant is currently approved for use up to 3 years. This study is looking to evaluate the contraceptive efficacy of Nexplanon during extended use for 2 more years (5 years total). You may be eligible if you are between the ages of 18-35 and are approaching 36 months from placement of your Nexplanon implant. Study participation…
Condition: Healthy Volunteers
Investigator: Gil Eyal, PhD
Status: Closed
Participants will complete a virtual interview over Zoom lasting about 1 hour. Questions will explore participants' understanding of the relationship between sexual behavior, identity, and genetics. Individuals ages 18 and over of all sexual and gender identities are eligible.
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
The HIV Vaccine Trials Network, Division of AIDS, and Columbia University Irving Medical Center are conducting a trial to learn about the safety and effectiveness of 3 experimental HIV vaccines. This is a first-in-human phase 1 clinical trial of experimental HIV vaccines utilizing the mRNA vaccine platform. The 3 different experimental vaccines being tested…
Condition: Healthy Volunteers
Investigator: Mariam Aly, PhD
Status: Closed
This study examines the effects of ecological uncertainty and threat on learning and memory in a navigation context, and the psychological factors that predict individual differences. If you choose to participate you can earn up to $20, including incentive pay. The study will take approximately 1.5-2 hours to complete.
Condition: Healthy Volunteers
Investigator: Elizabeth Sublette, MD, PhD
Status: Closed
This research study uses non-invasive brain imaging called functional near-infrared spectroscopy (fNIRS). For fNIRS, a small infrared bulb shines light through the skull, and a special light detector is able to measure oxygen use in the brain. Our goal is to understand oxygen use by brain mitochondria cells in major depression and how this is affected by…
Condition: Healthy Volunteers
Investigator: Vidhu Thaker, MD
Status: Closed
We are interested in studying the health of you and your family. Our study involves completing an online survey about your and your family's health and behaviors, and giving us access to basic health information that includes you and your child's vitals, weight/height, and BMI. You can receive up to $25 in Amazon pay cards for your participation.…
Condition: Cancer / Leukemia
Investigator: Nicole Lamanna, MD
Status: Closed
This research study is evaluating an investigational drug, called cirmtuzumab, in combination with astandard drug, called ibrutinib (Imbruvica), as a possible treatment for patients with CLL/SLL or MCL. All cells in the body receive signals to grow and survive, but sometimes these signals get out of control, causing too much cell growth. When the growth of…
Condition: Healthy Volunteers
Investigator: S. Zev Williams, MD, PhD
Status: Closed
Researchers at the Columbia University Fertility Center (CUFC) have collaborated with Princeton to learn more about the changes that occur infertility as women get older. We are looking for women between the ages of 20 and 50 who are not pregnant. The study involves a one time blood draw (3 small tubes) and a questionnaire. Visits take less than an hour.…
Condition: Healthy Volunteers
Investigator: Katherine Crew, MD
Status: Closed
The purpose of this randomized controlled trial (RCT) is to evaluate a decision support website (RealRisks) designed to inform patients about breast cancer prevention options. It is coupled with a physician-centered (BNAV) decision support website as part of clinical workflow in the primary care setting. The investigators hypothesize that improving accuracy…
Condition: Cancer / Leukemia
Investigator: Mark Heaney, MD, PhD
Status: Closed
The purpose of this study is to find out what dose of pacritinib is safest and works best for participants. Pacritinib is an experimental drug, which is a drug that is being tested and is not currently approved by the Food and Drug Administration (FDA) in the US. The study will be conducted at about 85 study clinics in North America, Europe, Israel and…
Condition: Healthy Volunteers
Investigator: Marie-Pierre St-Onge, PhD
Status: Closed
The overall goal of this research study is to find out if a new behavioral intervention can help people to improve their sleep quality. Our hope is to develop an effective and feasible behavioral approach that can benefit sleep in people from the general population. We are currently looking for 18-65 years old men and women, with no diagnosis of sleep…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
The purpose of this study is to: Test if the lifespan of study participants is increased when uproleselan is added to standard chemotherapy medicines compared to standard chemotherapy alone; test if the number of study participants achieving disease remission is increased when uproleselan is added to standard chemotherapy medicines compared to standard…
Condition: Cancer / Leukemia
Investigator: Nicole Lamanna, MD
Status: Closed
This study is being done to see how well tolerated the investigational drug TGR-1202 is in comparison to other similar therapeutics agents in treating patients with chronic lymphocytic leukemia (CLL).
Condition: Healthy Volunteers
Investigator: Franklin Schneier, MD
Status: Closed
We are currently enrolling healthy individuals to participate in a research study involving electroencephalography (EEG) and magnetic resonance imaging (MRI). Participants will complete 3 visits over the course of 2 weeks and receive up to $400 for their participation. The visits will involve a psychiatric assessment and medical history, playing computer…
Condition: Healthy Volunteers
Investigator: Kimberly Morel, MD
Status: Closed
This clinical study is being conducted for research purposes. The study cream, SD-101 (Zorblisa), has allantoin as the active ingredient and is being investigated for the treatment of the skin lesions which occur in patients with Epidermolysis Bullosa. The purpose of this clinical study is to study the effectiveness and safety of SD-101 (Zorblisa) in…
Condition: Healthy Volunteers
Investigator: Billy Caceres, PhD, RN
Status: Closed
This goal of this study is to learn more about how stress and coping might be associated with blood pressure in lesbian, gay, and bisexual adults. If you are deemed eligible, first you will be scheduled for a telephone or video conference interview with a member from the study team, which may take up to 1.5 hours. For the interview, you may be asked to…
Condition: Healthy Volunteers
Investigator: Kevin Ochsner, PhD
Status: Closed
The Social Cognitive and Affective Neuroscience (SCAN) Lab is currently running research studies to investigate social interactions. Our beliefs about those who are close to us are based on our previous interactions with them. This experiment examines exactly how interactions with close others lead to changes in our beliefs about their personality and our…
Condition: Cancer / Leukemia
Investigator: Mark Heaney, MD, PhD
Status: Closed
This is a clinical research study for subjects with Myelofibrosis (Primary, Post-Polycythemia Vera, and Post-Essential Thrombocytopenia) and thrombocytopenia. The purpose of this study is to determine if pacritinib is better at reducing spleen size and a reduction in symptoms than the best available therapy. This is a randomized, controlled study.…
Condition: Healthy Volunteers
Investigator: Micaela Martinez, PhD
Status: Closed
This study involves wearing a small light sensor on a lanyard and a temperature sensor in a wristband for one week in the summer, fall, winter and spring. The study will span 9 months. Participants will also be asked to fill out a daily questionnaire during those weeks. $30/week compensation or $120 in total for participation.
Condition: Healthy Volunteers
Investigator: Eldad Hod, MD
Status: Closed
This study is for healthy volunteers. Volunteers who agree to be part of this research will be requested to donate up to 4 tube(s) of blood (approximately 4 teaspoons). The blood will be tested for 5 standard clotting assays. Volunteers will be asked to fill out a questionnaire as well. Compensation for completion of this study is $20.
Condition: Cancer / Leukemia
Investigator: Daniel Lee, MD
Status: Closed
The purpose of this research study is to determine the preliminary safety and effectiveness (how well something works) of alvocidib when used after the standard drug decitabine in patients with MDS. The study will also gain information about the PK (the process by which a drug is absorbed, distributed, metabolized and eventually eliminated by the body),…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
The main purpose of this study is to see how effective an investigational new drug (tipifarnib, the study drug) is to treat myelodysplastic syndrome (MDS). "Investigational" means that tipifarnib has not yet been approved by regulatory authorities such as the United States Food and Drug Administration (FDA) for use outside of clinical trials. You…
Condition: Healthy Volunteers
Investigator: Christine Kim Garcia, MD
Status: Closed
The FAR-ILD study is designed to detect and study the earliest stages of ILD in adults with a family history of ILD. FAR-ILD is a non-interventional study. This means that FAR-ILD is not involved in testing any new interventions or therapies. The purpose of FAR-ILD is to gather data on family members of patients with pulmonary fibrosis over a long period of…
Condition: Cancer / Leukemia
Investigator: Daniel Lee, MD
Status: Closed
The purpose of this research study is to find out if the study drug MBG453 in combination with other drugs (decitabine or azacitidine) already commonly used to treat MDS is safe and has beneficial effects in people who have some types of MDS like you (intermediate, high, or very high risk MDS). Subjects will be administered the study treatment as indicated…
Condition: Cancer / Leukemia
Investigator: Nicole Lamanna, MD
Status: Closed
The purpose of this study, which involves research, is to determine if an experimental drug: acalabrutinib is safe and effective in the treatment of this patients with High Risk Chronic Lymphocytic Leukemia (CLL). Acalabrutinib is an investigational drug, which means that it is still being tested in people and has not been approved by government agencies in…
Condition: Healthy Volunteers
Investigator: Joyce Yu, MD
Status: Closed
The population includes males and females of all ages with one or more food allergy or those who are at risk of mortality from food-induced anaphylaxis. The FARE Patient Registry is a multicenter, prospective, longitudinal, observational cohort study of patients with food allergy. The participant and the treating physician agree that he/she will complete…
Condition: Healthy Volunteers
Investigator: Erika Berman-Rosenzweig, MD
Status: Closed
This research study is being conducted to study pulmonary hypertension and right heart dysfunction based on clinical, imaging, physiological and pathological characteristics. We hope to develop a new classification system and new methods to diagnose and treat pulmonary hypertension. Diagnostic testing includes (listed subsequently): full medical work-up,…
Condition: Healthy Volunteers
Investigator: Yael Cycowicz, Ph.D.
Status: Closed
This study investigates changes in brain responses to visual images presented both frequently and infrequently. 60 adults will be recruited for the study which will take place in a laboratory at the New York State Psychiatric Institute. You will see the visual images on a computer screen and will have to respond with a button press to only one image while…
Condition: Cancer / Leukemia
Investigator: Mark Heaney, MD, PhD
Status: Closed
We are doing this study to find out if an investigational drug called CPI-0610 can help with myelofibrosis. An investigational drug is a drug that is not approved for sale in the United States by the Food and Drug Administration (FDA). This study has two groups (arms) one group of patients will be treated with CPI-0610 alone (monotherapy arm) and the other…
Condition: Cancer / Leukemia
Investigator: Ran Reshef, MD
Status: Closed
The purpose of this research study is to obtain information on the safety and effectiveness of PBCAR20A to treat certain types of cancers. PBCAR20A is a new investigational treatment for certain types of cancer of the blood, such as leukemia and lymphoma. It is made from a type of blood cells known as T cells. The T cells in PBCAR20A came from healthy…
Condition: Healthy Volunteers
Investigator: Billy Caceres, PhD, RN
Status: Closed
The goal of this study is to conduct interviews with lesbian, gay, bisexual, transgender, and queer (LGBTQ) adults ages 40-64 years to explore sources of stress, stress management techniques, and heart disease risk behaviors (such as smoking). We will also identify preferred modalities for a stress management intervention to reduce heart disease risk in…
Condition: Cancer / Leukemia
Investigator: Mark Frattini, MD, PhD
Status: Closed
Pevonedistat is currently being studied in humans with advanced solid tumors and acute myelogenous leukemia (AML). The current study is designed to evaluate pevonedistat in combination with azacitidine in patients with myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML), and low-blast AML. This study will assess whether taking…
Condition: Healthy Volunteers
Investigator: Yuval Neria, PhD
Status: Closed
Emerging research has demonstrated a relationship between visual attention patterns and anxiety disorders, including PTSD. This study is designed to examine these visual attention patterns using eye-tracking A simple device that monitors eye-movements. The study included two sessions conducted approximately 1 week apart, each no longer than 1 hour. In both…
Condition: Healthy Volunteers
Investigator: Yuval Neria, PhD
Status: Closed
Columbia University Medical Center is presently recruiting healthy individuals to participate in an fMRI research study. For your participation, you will receive up to $270 and an opportunity to advance research in the area of trauma and PTSD. This study involves two visits.
Condition: Healthy Volunteers
Investigator: Lawrence Kegeles, MD
Status: Closed
PAID RESEARCH VOLUNTEERS NEEDED Healthy volunteers, age 18-35 years, needed for a research study. Study requirements:- 2-3 hours of clinical assessments and neurocognitive testing -1 hour MRI As a participant you will receive: $100 for the MRI; $10/ hour for other testing; participants can make up to $200.00 For further information about the study and your…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
The purpose of this part of the study is to obtain further information about the safety and effectiveness(how well it works) of azacitidine plus birinapant (the investigational drug), in people with higher-risk myelodysplastic syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMMoL). One of the standard drugs for these diseases is azacitidine which all…
Condition: Healthy Volunteers
Investigator: Helen Simpson, MD, PhD
Status: Closed
The purpose of this research study is to learn whether exercise affects learning and memory in people with anxiety. This is not a treatment study. The exercise program in this study runs for 6 weeks total. Each week, you are required to exercise 4 times for 12-15 minutes on the stepper machine that will be provided for you. You will be asked to visit our…
Condition: Healthy Volunteers
Investigator: Elizabeth Shane, MD
Status: Closed
Osteoporotic fractures affect the lives of 1.5 million Americans each year. Imaging tests, such as bone density, are used to predict fracture risk and to help guide therapy for fracture prevention. In this study we are validating a high-resolution, three-dimensional scanner with the overall goal of improving the diagnosis of bone diseases.
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
Antibodies are one of the natural ways that our bodies fight or prevent infection. Were testing an antibody to find out if its safe, if they don't make people feel uncomfortable, how these study antibodies move throughout the body, and to measure antiviral activity. You cannot get HIV from the study antibody. Firstly, request to be contacted by our…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
The purpose of this study is to test the safety and effectiveness of avapritinib (also known as BLU-285) in individuals who have been diagnosed with aggressive systemic mastocytosis (ASM), Systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell Leukemia (MCL). Avapritinib is an experimental drug means that is is not yet known if…
Condition: Healthy Volunteers
Investigator: Melanie Gold, MD
Status: Closed
Auriculotherapy is a type of Eastern medicine that has been used for thousands of years involving the ear. The ear has nerve connections to the whole body, and therefore using non-invasive techniques can be used to treat a wide variety of problems. This study is looking to see if auriculotherapy might be used to treat abdominal pain and find areas on the…
Condition: Cancer / Leukemia
Investigator: Mark Heaney, MD, PhD
Status: Closed
The purpose of this study is to determine how well a drug called rigosertib works on people with MDS and to study the safety of rigosertib when it is given to people with MDS. Rigosertib is currently being tested in other clinical research studies.
Condition: Healthy Volunteers
Investigator: Christine Kim Garcia, MD
Status: Closed
Are you a current or former smoker? Do you want to know more about your lung health? The FAR-ILD study is designed to detect and study the earliest stages of ILD in at-risk adults, including older smokers. FAR-ILD is a non-interventional study. This means that FAR-ILD is not involved in testing any new interventions or therapies. The purpose of FAR-ILD is…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
The purpose of the study is to see if a medicine called ASP2215 is both effective and safe as atreatment for AML patients with mutations in FLT3 gene identified by an investigational FLT3Mutation Assay companion diagnostic (a specific way to test your blood or bone marrow, which is used to see if you have a mutation of the FLT3 gene), compared to salvage…
Condition: Healthy Volunteers
Investigator: Martha Welch, MD
Status: Closed
The purpose of this current study is to investigate the efficacy of a group model of Family NurtureIntervention in ameliorating behavioral problems in preschool-aged children. The behavioral, neurobiological and clinical insights gained from this project may eventually lead to better treatment of emotional, behavioral and developmental disorders. The…
Condition: Healthy Volunteers
Investigator: Adam Brickman, PhD
Status: Closed
This study is associated with the Alzheimer's Disease Research Center (ADRC) at Columbia University. The study seeks to understand changes in the way the brain's structure and function are related to age, and the risk of developing memory problems, Alzheimer's disease (AD), and dementia. The study will use magnetic resonance imaging (MRI) to…
Condition: Healthy Volunteers
Investigator: Nim Tottenham, PhD
Status: Closed
Parents! Join our research study! For families with 2-4 years olds, Complete from the comfort of your own home! Involves: Complete questionnaires; Collect a stool sample from your child; Provided with an easy to use kit and video instructions; Earn $25 for participating.
Condition: Healthy Volunteers
Investigator: Carmela Alcantara, PhD
Status: Closed
The Latino Sleep and Health Study (LASH) is a community study of Latino adults that is focused on understanding the relationship between sleep, stress, self-control, and health. Participation in LASH is fairly simple. If you are found eligible after taking the screener, you will be asked to complete an in-person survey. You can earn $20 for after completing…
Condition: Cancer / Leukemia
Investigator: Azra Raza, MD
Status: Closed
The purpose of the study is to evaluate the efficacy and safety of imetelstat for the treatment of patients with myelodysplastic syndrome (MDS). All patients participating in Part 1 of this study will get 7.5 mg/kg of imetelstat as a 2-hour intravenous infusion once every 4 weeks. The dose of imetelstat may be increased, held or decreased depending on how…
Condition: Healthy Volunteers
Investigator: Sharon Mannheimer, MD
Status: Closed
This is a COVID transmission study happening across the US to help us learn whether the COVID-19 vaccine stops the spread of the SARS-CoV-2 virus (COVID): both initial infection and transmission to others. The answer to this question can have an important impact on all of our lives. Currently we are enrolling unvaccinated people. You will not be required to…
Condition: Cancer / Leukemia
Investigator: Daniel Lee, MD
Status: Closed
The purpose of this research study is to determine the effectiveness (how well something works) and safety of an investigational compound called alvocidib when used in a combination chemotherapy therapy regimen in patients with acute myeloid leukemia (AML) who test positive for NOXA priming.
Condition: Healthy Volunteers
Investigator: Keith Diaz, PhD
Status: Closed
The phrase sitting is the new smoking has been coined due to an increase of excessive sitting in middle- and older-aged adults. However, there are currently no specific guidelines for the best way to break up long periods of sitting. This study will look at the effect of breaking up sitting periods with movement breaks on blood sugar levels. We are looking…
Condition: Healthy Volunteers
Investigator: Thomas Nickolas, MD, MS
Status: Closed
The BoneGN study will help us learn how bones and muscles are responding to Glomerular Diseases. These conditions may gradually weaken bones and increase the risk of having a fracture (broken bone). In the future, the results can contribute in developing strategies to improve the bone health. We are looking for healthy children and adults between 5 and 55…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
The purpose of this study is to see if a medicine called ASP2215 is both safe and effective as atreatment for patients with Acute Myeloid Leukemia (AML). ASP2215 is an experimental drug that is being studied to treat AML. In this study, ASP2215 will be given in addition to a standard chemotherapy regimen that patients could be receiving even if they were…
Condition: Healthy Volunteers
Investigator: Micaela Martinez, PhD
Status: Closed
How does the light we experience in day-to-day life affect our body clock? Interested in joining a new project to help scientists at Columbia University understand how light pollution and light-at-night affects our body clock? You or your child may be eligible to participate. The study involves wearing a small light sensor on a lanyard and a temperature…
Condition: Healthy Volunteers
Investigator: Marla Hamberger, PhD
Status: Closed
Some medical conditions in children involve difficulty with speech and language. Therefore, accurate measurement of these difficulties is important for both diagnosis and treatment. Unfortunately, the test that is currently used to assess object naming-- one of the most common language problems found in these conditions is the same test that is used for…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
Almost 40,000 people get HIV in the U.S. each year and almost all occur via sexual contact, especially male-to-male contact. The number of new infections has decreased slightly each year, however, we need other HIV prevention tools, such as developing a greatly, effective HIV vaccine, to better reduce HIV infections. SCREENING AND EDUCATION: 1. Consent will…
Condition: Healthy Volunteers
Investigator: Magdalena Sobieszczyk, Md
Status: Closed
Antibodies are one of the natural ways that our bodies fight or prevent infection. Were testing an antibody to find out if its safe, if it doesn't make people feel uncomfortable and to find out what may be the best dose if its given by IV infusion or sub-cutaneous injection. You cannot get HIV from the Bispecific Antibody. We'll ask you to…
Condition: Cancer / Leukemia
Investigator: Monica Bhatia, MD
Status: Closed
The purpose of this study is to compare two different combinations of treatment plans to a standard transplant procedure in order to see whether one or both of them are better at reducing the occurrence and severity of chronic GVHD. The research portion of this study involves manipulation of your stem cell product by removing T-cells, which cause chronic…
Condition: Cancer / Leukemia
Investigator: Mark Heaney, MD, PhD
Status: Closed
You are being asked to take part in this study because you have been diagnosed with Myeloproliferative neoplasm (MPN) Associated Myelofibrosis (your disease) and have received ruxolitinib. The purpose of this study is to confirm how well this study treatment works to reduce your spleen volume, spleen size, what effect the study treatment has on you and…
Condition: Cancer / Leukemia
Investigator: Nicole Lamanna, MD
Status: Closed
The purpose of the study is to see if a combination of idelalisib and BI 836826 can help control patients with Chronic Lymphocytic Leukemia (CLL) without serious side effects.
Condition: Healthy Volunteers
Investigator: Allison Borowski, MD
Status: Closed
We are currently recruiting women to TMIST, a clinical trial that will help us develop strategies that tailor breast cancer screening to the risks of individual women. This is a screening trial. The purpose of this trial is to determine if tomosynthesis (3-D) mammography detects breast cancer at earlier stage than current method of 2-D digital mammography.
Condition: Healthy Volunteers
Investigator: Karen Bell, MD
Status: Closed
The purpose of this study is to test whether an investigational drug called solanezumab can slow the progression of memory problems associated with brain amyloid. The study will also test 1) whether the anti-amyloid treatment can slow evidence of AD-related brain injury on imaging tests to look at brain structure and function and 2) the effect of…
Condition: Healthy Volunteers
Investigator: Helen Simpson, MD, PhD
Status: Closed
Obssesive Compulsive Disorder (OCD) and related disorders characterized by repetitive thoughts and behaviors (e.g., Tourette Syndrome and Eating Disorders) are severe conditions that lead to significant health-related disability. Dysfunction in the brain circuits involved in cognitive control and reward processing are thought to contribute to the symptoms…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
The purpose of this study is to test the safety of DCLL9718S at different dose levels, alone or in combination with azacitidine. DCLL9718S is an experimental drug manufactured by Genentech that is designed to inhibit tumor growth. The drug is being tested in clinical trials and has not been approved by the U.S. Food and Drug Administration (FDA) and/or any…
Condition: Cancer / Leukemia
Investigator: Daniel Lee, MD
Status: Closed
You are being asked to take part in this study because you have acute myeloid leukemia (AML) that has come back after initial treatment (relapsed) with venetoclax combination therapy or because you did not get a complete response from your initial treatment (refractory) with venetoclax combination therapy. The purpose of this research study is to determine…
Condition: Cancer / Leukemia
Investigator: Todd Rosenblat, MD
Status: Closed
The goal of this research study is to find the safest highest dose of SL-401 that can be given to patients with AML or BPDCN. This study will also look at how SL-401 stops or slows leukemia or BPDCN growth and how SL-401 enters and leaves the body. This study will also look at certain proteins in the blood and bone marrow and how the amounts of them might…
Condition: Healthy Volunteers
Investigator: Loren Gianini, PhD
Status: Closed
The goal of this study is to better understand why some people have managed to lose weight and keep it off while others have not. We are recruiting people who have lost weight and kept it off as well as healthy non-dieters with overweight or obesity who are not trying to lose weight. Study participation involves computer tasks, brain imaging, and eating a…
Condition: Healthy Volunteers
Investigator: Yaakov Stern, PhD
Status: Closed
Train the Brain Study: The purpose of this study is to investigate the effect of a web-based (remote, at home) computerized cognitive training protocol on cognitive performance in healthy older adults. Thetraining will involve a daily life situation in a multi-task context. If you are eligible, you will be asked tocomplete 13 web-based sessions, twice a…
Condition: Cancer / Leukemia
Investigator: Joseph Jurcic, MD
Status: Closed
The purpose of this study is to determine if oral azacitidine (CC-486) is safe and effective as maintenance therapy in continuing the response patients had with their last acute myeloid leukemia (AML) treatment and improving the quality of that response. Currently, there is no standard treatment to maintain or improve patient response and patients are…
Condition: Healthy Volunteers
Investigator: Marla Hamberger, PhD
Status: Closed
The purpose of this project is to develop a set of word finding or naming tests for adults, ages 66 and above. The main task involves naming pictures of common objects (e.g. broom), or naming items when given a description (e.g. "what children ride to school in"). There are some other tasks as well such as single word reading, number repetition,…
Condition: Healthy Volunteers
Investigator: Cassia Wells, MD
Status: Closed
Antibodies are one of the natural ways that our bodies fight or prevent infection. We're testing an antibody to find out if it's safe, if they don't make people feel uncomfortable, how these study antibodies move throughout the body, and to measure antiviral activity. You cannot get HIV from the study antibody. First, request to be contacted…
Determining Changing in Cardiovascular and Metabolic Risks in Patients with Chronic Myeloid Leukemia
Condition: Cancer / Leukemia
Investigator: Mark Heaney, MD, PhD
Status: Closed
This study will see how the treatment you will receive for your chronic myeloid leukemia affects cardiovascular and metabolic risk factors. The treatments that are being studied are called BCR-ABL1 tyrosine kinase inhibitors (TKIs) (i.e., dasatinib, imatinib, nilotinib). Subjects who are eligible for the study will be starting treatment for chronic myeloid…